8QQE
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![BU of 8qqe by Molmil](/molmil-images/mine/8qqe) | Crystal structure of the complex between DMC1 and the PhePP domain of BRCA2 | Descriptor: | Breast cancer type 2 susceptibility protein, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Miron, S, Legrand, P, Zinn-Justin, S. | Deposit date: | 2023-10-04 | Release date: | 2024-06-19 | Last modified: | 2024-07-17 | Method: | X-RAY DIFFRACTION (3.461 Å) | Cite: | DMC1 and RAD51 bind FxxA and FxPP motifs of BRCA2 via two separate interfaces. Nucleic Acids Res., 52, 2024
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7OZ0
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4RQI
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![BU of 4rqi by Molmil](/molmil-images/mine/4rqi) | Structure of TRF2/RAP1 secondary interaction binding site | Descriptor: | GLYCEROL, MAGNESIUM ION, Telomeric repeat-binding factor 2, ... | Authors: | Miron, S, Guimaraes, B, Gaullier, G, Giraud-Panis, M.-J, Gilson, E, Le Du, M.-H. | Deposit date: | 2014-11-03 | Release date: | 2016-02-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4405 Å) | Cite: | A higher-order entity formed by the flexible assembly of RAP1 with TRF2. Nucleic Acids Res., 44, 2016
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6GY2
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![BU of 6gy2 by Molmil](/molmil-images/mine/6gy2) | |
1P4S
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8A50
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![BU of 8a50 by Molmil](/molmil-images/mine/8a50) | Crystal structure of HSF2BP-ALPHA1 tetramer | Descriptor: | Heat shock factor 2-binding protein, PHOSPHATE ION | Authors: | Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S. | Deposit date: | 2022-06-13 | Release date: | 2023-07-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.484 Å) | Cite: | BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Sci Adv, 9, 2023
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8A51
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![BU of 8a51 by Molmil](/molmil-images/mine/8a51) | Crystal structure of HSF2BP-BRME1 complex | Descriptor: | 1,2-ETHANEDIOL, Break repair meiotic recombinase recruitment factor 1, CHLORIDE ION, ... | Authors: | Miron, S, Legrand, P, Ropars, V, Ghouil, R, Zinn-Justin, S. | Deposit date: | 2022-06-13 | Release date: | 2023-07-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination. Sci Adv, 9, 2023
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3KF9
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![BU of 3kf9 by Molmil](/molmil-images/mine/3kf9) | Crystal structure of the SdCen/skMLCK complex | Descriptor: | CALCIUM ION, Caltractin, Myosin light chain kinase 2, ... | Authors: | Radu, L, Assairi, L, Blouquit, Y, Durand, D, Miron, S, Charbonnier, J.B, Craescu, C.T. | Deposit date: | 2009-10-27 | Release date: | 2011-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural features of the complexes formed by Scherffelia dubia centrin To be Published
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7BDX
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![BU of 7bdx by Molmil](/molmil-images/mine/7bdx) | Armadillo domain of HSF2BP in complex with BRCA2 peptide | Descriptor: | Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein, MAGNESIUM ION | Authors: | Le Du, M.H, Zinn-Justin, S, Ghouil, R, Miron, S, Legrand, P. | Deposit date: | 2020-12-22 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | BRCA2 binding through a cryptic repeated motif to HSF2BP oligomers does not impact meiotic recombination. Nat Commun, 12, 2021
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1M39
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![BU of 1m39 by Molmil](/molmil-images/mine/1m39) | Solution structure of the C-terminal fragment (F86-I165) of the human centrin 2 in calcium saturated form | Descriptor: | Caltractin, isoform 1 | Authors: | Matei, E, Miron, S, Blouquit, Y, Duchambon, P, Durussel, P, Cox, J.A, Craescu, C.T. | Deposit date: | 2002-06-27 | Release date: | 2003-03-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | C-terminal half of human centrin 2 behaves like a regulatory EF-hand domain Biochemistry, 42, 2003
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1ZMZ
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![BU of 1zmz by Molmil](/molmil-images/mine/1zmz) | Solution structure of the N-terminal domain (M1-S98) of human centrin 2 | Descriptor: | Centrin-2 | Authors: | Yang, A, Miron, S, Duchambon, P, Assairi, L, Blouquit, Y, Craescu, C.T. | Deposit date: | 2005-05-11 | Release date: | 2006-04-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The N-terminal domain of human centrin 2 has a closed structure, binds calcium with a very low affinity, and plays a role in the protein self-assembly Biochemistry, 45, 2006
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2A4J
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![BU of 2a4j by Molmil](/molmil-images/mine/2a4j) | Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein | Descriptor: | 17-mer peptide P1-XPC from DNA-repair protein complementing XP-C cells, Centrin 2 | Authors: | Yang, A, Miron, S, Mouawad, L, Duchambon, P, Blouquit, Y, Craescu, C.T. | Deposit date: | 2005-06-29 | Release date: | 2005-07-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein (XPC) from nuclear excision repair. Biochemistry, 45, 2006
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