4NM2
 
 | | Structure of human DNA polymerase beta complexed with a nicked DNA containing a 8BrG-G at N-1 position and G-C at N position | | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*GP*(BGM)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | Deposit date: | 2013-11-14 | | Release date: | 2014-01-22 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.524 Å) | | Cite: | Structural basis for promutagenicity of 8-halogenated Guanine.
J.Biol.Chem., 289, 2014
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4NXZ
 | | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable TTP with manganese in the active site | | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | Deposit date: | 2013-12-09 | | Release date: | 2014-04-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.557 Å) | | Cite: | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
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4NY8
 | | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, 5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', ... | | Authors: | Koag, M.-C, Min, K, Monzingo, A.F, Lee, S. | | Deposit date: | 2013-12-10 | | Release date: | 2014-04-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.246 Å) | | Cite: | Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
J.Am.Chem.Soc., 136, 2014
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7AJP
 | | Crystal Structure of Human Adenovirus 56 Fiber Knob | | Descriptor: | 1,2-ETHANEDIOL, Fiber, GLYCEROL, ... | | Authors: | Strebl, M, Mindler, K, Stehle, T. | | Deposit date: | 2020-09-29 | | Release date: | 2021-01-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.382018 Å) | | Cite: | Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4V0Q
 | | Dengue Virus Full Length NS5 Complexed with SAH | | Descriptor: | ACETATE ION, GLYCEROL, NS5 POLYMERASE, ... | | Authors: | Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D. | | Deposit date: | 2014-09-18 | | Release date: | 2015-01-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
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5LV6
 | | N-terminal motif dimerization of EGFR transmembrane domain in bicellar environment | | Descriptor: | Epidermal growth factor receptor | | Authors: | Bragin, P, Bocharov, E, Mineev, K, Bocharova, O, Arseniev, A. | | Deposit date: | 2016-09-12 | | Release date: | 2017-04-05 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane Environment.
Biochemistry, 56, 2017
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4XZX
 | | Shigella flexneri effector OspI C62S mutant | | Descriptor: | ACETATE ION, ORF169b | | Authors: | Nishide, A, Takagi, K, Minsoo, K, Sasakawa, C, Mizushima, T. | | Deposit date: | 2015-02-05 | | Release date: | 2016-02-10 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | New insights into the active site structure of Shigella effecter OspI
To Be Published
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8AO1
 | | solution structure of nanoFAST fluorogen-activating protein in the apo state | | Descriptor: | nanoFAST | | Authors: | Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baranov, M.S, Mineev, K.S. | | Deposit date: | 2022-08-08 | | Release date: | 2022-11-23 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
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8AO0
 | | Solution structure of nanoFAST/HBR-DOM2 complex | | Descriptor: | (5~{Z})-5-[(2,5-dimethoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Photoactive yellow protein | | Authors: | Lushpa, V.A, Goncharuk, M.V, Goncharuk, S.A, Baleeva, N.S, Baranov, M.S, Mineev, K.S. | | Deposit date: | 2022-08-08 | | Release date: | 2022-11-23 | | Method: | SOLUTION NMR | | Cite: | Spatial Structure of NanoFAST in the Apo State and in Complex with its Fluorogen HBR-DOM2.
Int J Mol Sci, 23, 2022
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8AR3
 | | Solution structure of TLR9 transmembrane and cytoplasmic juxtamembrane regions | | Descriptor: | Toll-like receptor 9 | | Authors: | Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S. | | Deposit date: | 2022-08-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
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8AR0
 | | Solution structure of TLR2 transmembrane and cytoplasmic juxtamembrane regions | | Descriptor: | Toll-like receptor 2 | | Authors: | Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S. | | Deposit date: | 2022-08-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
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8AR2
 | | Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions | | Descriptor: | Toll-like receptor 5 | | Authors: | Shabalkina, A.V, Kornilov, F.D, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S. | | Deposit date: | 2022-08-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
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8AR1
 | | Solution structure of TLR3 transmembrane and cytoplasmic juxtamembrane regions | | Descriptor: | Toll-like receptor 3 | | Authors: | Kornilov, F.D, Shabalkina, A.V, Goncharuk, M.V, Goncharuk, S.A, Arseniev, A.S, Mineev, K.S. | | Deposit date: | 2022-08-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors.
Nat Commun, 14, 2023
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6E0A
 | | Crystal Structure of Helicobacter pylori TlpA Chemoreceptor Ligand Binding Domain | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Remington, S.J, Guillemin, K, Sweeney, E, Perkins, A. | | Deposit date: | 2018-07-06 | | Release date: | 2018-09-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structures of the ligand-binding domain of Helicobacter pylori chemoreceptor TlpA.
Protein Sci., 27, 2018
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8C18
 | | Solution structure of carotenoid-binding protein AstaPo1 in complex with astaxanthin | | Descriptor: | ASTAXANTHIN, Astaxanthin binding fasciclin family protein | | Authors: | Kornilov, F.D, Savitskaya, A.G, Slonimskiy, Y.B, Goncharuk, S.A, Sluchanko, N.N, Mineev, K.S. | | Deposit date: | 2022-12-20 | | Release date: | 2023-04-05 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP.
Commun Biol, 6, 2023
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6E09
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6DTM
 | | Crystal Structure of Helicobacter pylori TlpA Chemoreceptor Ligand Binding Domain | | Descriptor: | CHLORIDE ION, Methyl-accepting chemotaxis protein TlpA | | Authors: | Remington, S.J, Guillemin, K, Sweeney, E, Perkins, A. | | Deposit date: | 2018-06-17 | | Release date: | 2018-09-12 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of the ligand-binding domain of Helicobacter pylori chemoreceptor TlpA.
Protein Sci., 27, 2018
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4XNN
 | | Crystal Structure of a GH7 Family Cellobiohydrolase from Daphnia pulex | | Descriptor: | Cellobiohydrolase CHBI, GLYCEROL | | Authors: | Ebrahim, A, Hobdey, S.E, Podkaminer, K, Taylor II, L.E, Beckham, G.T, Decker, S.R, Himmel, M.E, Cragg, S.M, McGeehan, J.E. | | Deposit date: | 2015-01-15 | | Release date: | 2016-01-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Characterization of a GH7 Family Cellobiohydrolase from Daphnia pulex
To Be Published
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5WVX
 | | Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID, Trypsin/chymotrypsin inhibitor | | Authors: | Palayam, M, Radhakrishnan, M, Lakshminarayanan, K, Balu, K.E, Ganapathy, J, Krishnasamy, G. | | Deposit date: | 2016-12-29 | | Release date: | 2018-06-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Int. J. Biol. Macromol., 113, 2018
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6HJ7
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3FHV
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7VNX
 | | Crystal structure of TkArkI | | Descriptor: | GUANOSINE, TkArkI | | Authors: | Yamashita, S, Minowa, K, Ohira, T, Suzuki, T, Tomita, K. | | Deposit date: | 2021-10-12 | | Release date: | 2022-05-04 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance.
Nature, 605, 2022
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8EVD
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7W7S
 | | High resolution structure of a fish aquaporin reveals a novel extracellular fold. | | Descriptor: | Aquaporin 1 | | Authors: | Zeng, J, Schmitz, F, Isaksson, S, Glas, J, Arbab, O, Andersson, M, Sundell, K, Eriksson, L, Swaminathan, K, Tornroth-Horsefield, S, Hedfalk, K. | | Deposit date: | 2021-12-06 | | Release date: | 2022-10-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | High-resolution structure of a fish aquaporin reveals a novel extracellular fold.
Life Sci Alliance, 5, 2022
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4URG
 | | Crystal Structure of GGDEF domain from T.maritima (active-like dimer) | | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DIGUANYLATE CYCLASE | | Authors: | Deepthi, A, Liew, C.W, Liang, Z.X, Swaminathan, K, Lescar, J. | | Deposit date: | 2014-06-30 | | Release date: | 2014-10-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a Diguanylate Cyclase from Thermotoga Maritima: Insights Into Activation, Feedback Inhibition and Thermostability
Plos One, 9, 2014
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