5J4C
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![BU of 5j4c by Molmil](/molmil-images/mine/5j4c) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (soaked) and bound to mRNA and A-, P- and E-site tRNAs at 2.8A resolution | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | 登録日 | 2016-03-31 | 公開日 | 2016-04-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
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6N9E
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![BU of 6n9e by Molmil](/molmil-images/mine/6n9e) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | 登録日 | 2018-12-03 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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6N9F
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![BU of 6n9f by Molmil](/molmil-images/mine/6n9f) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | 登録日 | 2018-12-03 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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5LYB
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![BU of 5lyb by Molmil](/molmil-images/mine/5lyb) | |
5J4B
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![BU of 5j4b by Molmil](/molmil-images/mine/5j4b) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with cisplatin (co-crystallized) and bound to mRNA and A-, P- and E-site tRNAs at 2.6A resolution | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Melnikov, S.V, Soll, D, Steitz, T.A, Polikanov, Y.S. | 登録日 | 2016-03-31 | 公開日 | 2016-04-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome. Nucleic Acids Res., 44, 2016
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5TGA
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![BU of 5tga by Molmil](/molmil-images/mine/5tga) | |
5TGM
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![BU of 5tgm by Molmil](/molmil-images/mine/5tgm) | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | 著者 | Melnikov, S, Mailliot, J, Yusupov, M. | 登録日 | 2016-09-28 | 公開日 | 2017-01-18 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
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5DC3
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![BU of 5dc3 by Molmil](/molmil-images/mine/5dc3) | Complex of yeast 80S ribosome with non-modified eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-23 | 公開日 | 2016-06-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome. J.Mol.Biol., 428, 2016
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5DGE
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![BU of 5dge by Molmil](/molmil-images/mine/5dge) | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-27 | 公開日 | 2017-01-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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5DAT
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![BU of 5dat by Molmil](/molmil-images/mine/5dat) | Complex of yeast 80S ribosome with hypusine-containing eIF5A | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-20 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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5DGF
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![BU of 5dgf by Molmil](/molmil-images/mine/5dgf) | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-27 | 公開日 | 2016-12-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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5DGV
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![BU of 5dgv by Molmil](/molmil-images/mine/5dgv) | Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog | 分子名称: | 25S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M. | 登録日 | 2015-08-28 | 公開日 | 2016-12-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome To Be Published
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5AGQ
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![BU of 5agq by Molmil](/molmil-images/mine/5agq) | Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes | 分子名称: | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A | 著者 | Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M. | 登録日 | 2015-02-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes. Nucleic Acids Res., 43, 2015
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4V88
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![BU of 4v88 by Molmil](/molmil-images/mine/4v88) | The structure of the eukaryotic ribosome at 3.0 A resolution. | 分子名称: | 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... | 著者 | Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. | 登録日 | 2011-10-11 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
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6GQ1
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![BU of 6gq1 by Molmil](/molmil-images/mine/6gq1) | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-07 | 公開日 | 2018-07-11 | 最終更新日 | 2018-08-08 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
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7QEP
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![BU of 7qep by Molmil](/molmil-images/mine/7qep) | Cryo-EM structure of the ribosome from Encephalitozoon cuniculi | 分子名称: | 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | 著者 | Nicholson, D, Ranson, N.A, Melnikov, S.V. | 登録日 | 2021-12-03 | 公開日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Adaptation to genome decay in the structure of the smallest eukaryotic ribosome Nat Commun, 13, 2022
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8RDV
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![BU of 8rdv by Molmil](/molmil-images/mine/8rdv) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2). | 分子名称: | 16S rRNA, 23S rRNA, 5S rRNA, ... | 著者 | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | 登録日 | 2023-12-08 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RDW
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![BU of 8rdw by Molmil](/molmil-images/mine/8rdw) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3). | 分子名称: | 16S rRNA, 23S rRNA, 5S rRNA, ... | 著者 | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | 登録日 | 2023-12-08 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8RD8
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![BU of 8rd8 by Molmil](/molmil-images/mine/8rd8) | Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1). | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ... | 著者 | Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V. | 登録日 | 2023-12-07 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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4Y4O
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![BU of 4y4o by Molmil](/molmil-images/mine/4y4o) | Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A. | 登録日 | 2015-02-10 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nat.Struct.Mol.Biol., 22, 2015
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4Y4P
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![BU of 4y4p by Molmil](/molmil-images/mine/4y4p) | Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to mRNA and A-, P- and E-site tRNAs at 2.5A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A. | 登録日 | 2015-02-10 | 公開日 | 2015-03-18 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly. Nat.Struct.Mol.Biol., 22, 2015
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8V9J
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![BU of 8v9j by Molmil](/molmil-images/mine/8v9j) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9K
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![BU of 8v9k by Molmil](/molmil-images/mine/8v9k) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9L
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![BU of 8v9l by Molmil](/molmil-images/mine/8v9l) | Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8UPT
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![BU of 8upt by Molmil](/molmil-images/mine/8upt) | Candidatus Methanomethylophilus alvus tRNAPyl in A-site of ribosome | 分子名称: | RNA (71-MER) | 著者 | Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D. | 登録日 | 2023-10-23 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut. Nucleic Acids Res., 52, 2024
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