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PDB: 90 件
6ZK7
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BU of 6zk7 by Molmil
Crystal Structure of human PYROXD1/FAD complex
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
著者Meinhart, A, Asanovic, I, Martinez, J, Clausen, T.
登録日2020-06-30
公開日2021-05-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
1GVN
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BU of 1gvn by Molmil
Crystal Structure of the Plasmid Maintenance System epsilon/zeta: Meachnism of toxin inactivation and toxin function
分子名称: EPSILON, SULFATE ION, ZETA
著者Meinhart, A, Alonso, J.C, Straeter, N, Saenger, W.
登録日2002-02-19
公開日2003-01-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of the Plasmid Maintenance System Epsilon /Zeta : Functional Mechanism of Toxin Zeta and Inactivation by Epsilon 2 Zeta 2 Complex Formation
Proc.Natl.Acad.Sci.USA, 100, 2003
1Q1H
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BU of 1q1h by Molmil
An extended winged helix domain in general transcription factor E/IIE alpha
分子名称: Transcription Factor E
著者Meinhart, A, Blobel, J, Cramer, P.
登録日2003-07-21
公開日2003-12-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献An Extended Winged Helix Domain in General Transcription Factor E/IIE alpha
J.Biol.Chem., 278, 2003
7AA4
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BU of 7aa4 by Molmil
Structure of ClpC1-NTD bound to a CymA analogue
分子名称: Negative regulator of genetic competence ClpC/mecB, polymer Cyclomarin A analogue
著者Meinhart, A, Morreale, F.E, Kaiser, M, Clausen, T.
登録日2020-09-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
分子名称: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-10
公開日2023-07-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
8B9O
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BU of 8b9o by Molmil
Structure of the C-terminal domain of ClpC2 from Mycobacterium smegmatis
分子名称: Clp amino terminal domain protein, phospho-arginine
著者Meinhart, A, Hoi, D.M, Clausen, T.
登録日2022-10-06
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
6QDL
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BU of 6qdl by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.929 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDM
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BU of 6qdm by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDK
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Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: UNC-45,UNC-45
著者Meinhart, A, Clausen, T, Hellerschmied, D.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
6QDJ
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BU of 6qdj by Molmil
Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin
分子名称: 1,4-BUTANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ADENOSINE-5'-DIPHOSPHATE, ...
著者Meinhart, A, Clausen, T, Arnese, R.
登録日2019-01-02
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.884 Å)
主引用文献Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun, 10, 2019
1SZA
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BU of 1sza by Molmil
The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
分子名称: CTD-peptide, PCF11 protein
著者Meinhart, A, Cramer, P.
登録日2004-04-05
公開日2004-07-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Nature, 430, 2004
1SZ9
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BU of 1sz9 by Molmil
The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
分子名称: PCF11 protein
著者Meinhart, A, Cramer, P.
登録日2004-04-05
公開日2004-07-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Nature, 430, 2004
2KM4
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BU of 2km4 by Molmil
Solution structure of Rtt103 CTD interacting domain
分子名称: Regulator of Ty1 transposition protein 103
著者Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G.
登録日2009-07-20
公開日2010-09-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
6EPH
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BU of 6eph by Molmil
Structure of the epsilon_1 / zeta_1 antitoxin toxin system from Neisseria gonorrhoeae in complex with UNAM.
分子名称: (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, CITRATE ANION, Epsilon_1 antitoxin, ...
著者Rocker, A, Meinhart, A.
登録日2017-10-11
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The ng_ zeta 1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.
Nat Commun, 9, 2018
6EPG
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BU of 6epg by Molmil
Structure of the epsilon_1 / zeta_1 antitoxin / toxin system from Neisseria gonorrhoeae.
分子名称: Epsilon_1 antitoxin, SULFATE ION, Zeta_1 toxin
著者Rocker, A, Meinhart, A.
登録日2017-10-11
公開日2018-05-02
最終更新日2018-05-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The ng_ zeta 1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.
Nat Commun, 9, 2018
6TV6
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BU of 6tv6 by Molmil
Octameric McsB from Bacillus subtilis.
分子名称: MAGNESIUM ION, Protein-arginine kinase
著者Suskiewicz, M.J, Hajdusits, B, Meinhart, A, Clausen, T.
登録日2020-01-09
公開日2021-07-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Elife, 10, 2021
6EPI
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BU of 6epi by Molmil
Structure of the epsilon_1 / zeta_1 antitoxin / toxin system from Neisseria gonorrhoeae in complex with UNAM-4P.
分子名称: CITRATE ANION, Epsilon_1 antitoxin, SULFATE ION, ...
著者Rocker, A, Meinhart, A.
登録日2017-10-11
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The ng_ zeta 1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis.
Nat Commun, 9, 2018
4XW3
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BU of 4xw3 by Molmil
Crystal structure of the SPRY domain of the human DEAD-box protein DDX1
分子名称: ATP-dependent RNA helicase DDX1
著者Kellner, J.N, Meinhart, A.
登録日2015-01-28
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein.
Acta Crystallogr.,Sect.F, 71, 2015
3ISM
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BU of 3ism by Molmil
Crystal structure of the EndoG/EndoGI complex: Mechanism of EndoG inhibition
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CG4930, CG8862, ...
著者Loll, B, Gebhardt, M, Wahle, E, Meinhart, A.
登録日2009-08-26
公開日2009-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the EndoG/EndoGI complex: mechanism of EndoG inhibition.
Nucleic Acids Res., 37, 2009
3Q8X
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BU of 3q8x by Molmil
Structure of a toxin-antitoxin system bound to its substrate
分子名称: Antidote of epsilon-zeta postsegregational killing system, SULFATE ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
著者Mutschler, H, Gebhardt, M, Shoeman, R.L, Meinhart, A.
登録日2011-01-07
公開日2011-03-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis.
Plos Biol., 9, 2011
8AMZ
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BU of 8amz by Molmil
Spinach 19S proteasome
分子名称: 26S proteasome non-ATPase regulatory subunit 1 homolog, 26S proteasome non-ATPase regulatory subunit 2 homolog, 26S proteasome regulatory subunit 7, ...
著者Kandolf, S, Grishkovskaya, I, Meinhart, A, Haselbach, D.
登録日2022-08-04
公開日2022-08-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the plant 26S proteasome
Plant Communications, 3, 2022
2L0I
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BU of 2l0i by Molmil
Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide
分子名称: DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103
著者Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G.
登録日2010-07-06
公開日2010-09-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
7ABR
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BU of 7abr by Molmil
Cryo-EM structure of B. subtilis ClpC (DWB mutant) hexamer bound to a substrate polypeptide
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Negative regulator of genetic competence ClpC/MecB, ...
著者Morreale, F.E, Meinhart, A, Haselbach, D, Clausen, T.
登録日2020-09-08
公開日2021-10-06
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献BacPROTACs mediate targeted protein degradation in bacteria.
Cell, 185, 2022
8BRH
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BU of 8brh by Molmil
Co-crystal structure of She4 with Myo4 peptide
分子名称: KLLA0E16699p, Myo4 peptide (LYS-PHE-ILE-VAL-SER-HIS-TYR)
著者Arnese, R, Gudino, R, Meinhart, A, Clausen, T.
登録日2022-11-23
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024
8BRG
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BU of 8brg by Molmil
Crystal structure of She4
分子名称: KLLA0E16699p
著者Gudino, R, Arnese, R, Meinhart, A, Clausen, T.
登録日2022-11-23
公開日2024-06-05
最終更新日2024-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献UNC-45 assisted myosin folding depends on a conserved FX 3 HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun, 15, 2024

 

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