6SCF
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![BU of 6scf by Molmil](/molmil-images/mine/6scf) | A viral anti-CRISPR subverts type III CRISPR immunity by rapid degradation of cyclic oligoadenylate | 分子名称: | Uncharacterized protein, cyclic oligoadenylate | 著者 | McMahon, S.A, Athukoralage, J.S, Graham, S, White, M.F, Gloster, T.M. | 登録日 | 2019-07-24 | 公開日 | 2019-10-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity. Nature, 577, 2020
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6SCE
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![BU of 6sce by Molmil](/molmil-images/mine/6sce) | Structure of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate | 分子名称: | Uncharacterized protein, cyclic oligoadenylate | 著者 | McMahon, S.A, Zhu, W, Graham, S, White, M.F, Gloster, T.M. | 登録日 | 2019-07-24 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure and mechanism of a Type III CRISPR defence DNA nuclease activated by cyclic oligoadenylate. Nat Commun, 11, 2020
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3FFE
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![BU of 3ffe by Molmil](/molmil-images/mine/3ffe) | Structure of Achromobactin Synthetase Protein D, (AcsD) | 分子名称: | AcsD | 著者 | McMahon, S.A, Liu, H, Carter, L, Oke, M, Johnson, K.A, Schmelz, S, Challis, G.L, White, M.F, Naismith, J.H, Scottish Structural Proteomics Facility (SSPF) | 登録日 | 2008-12-03 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis Nat.Chem.Biol., 5, 2009
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8QJK
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![BU of 8qjk by Molmil](/molmil-images/mine/8qjk) | Structure of the cytoplasmic domain of csx23 from Vibrio cholera in complex with cyclic tetra-adenylate (cA4) | 分子名称: | ACETYL GROUP, Cyclic tetraadenosine monophosphate (cA4), SODIUM ION, ... | 著者 | McMahon, S.A, McQuarrie, S, Gloster, T.M, Gruschow, S, White, M.F. | 登録日 | 2023-09-13 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.761 Å) | 主引用文献 | A cyclic-nucleotide binding membrane protein provides CRISPR-mediated antiphage defence in Vibrio cholera To Be Published
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1YU4
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![BU of 1yu4 by Molmil](/molmil-images/mine/1yu4) | Major Tropism Determinant U1 Variant | 分子名称: | MAGNESIUM ION, Major Tropism Determinant (Mtd-U1) | 著者 | McMahon, S.A, Miller, J.L, Lawton, J.A, Ghosh, P. | 登録日 | 2005-02-11 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The C-type lectin fold as an evolutionary solution for massive sequence variation Nat.Struct.Mol.Biol., 12, 2005
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1YU1
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![BU of 1yu1 by Molmil](/molmil-images/mine/1yu1) | Major Tropism Determinant P3c Variant | 分子名称: | MAGNESIUM ION, METHYL MERCURY ION, Major Tropism Determinant (Mtd-P3c) | 著者 | McMahon, S.A, Miller, J.L, Lawton, J.A, Ghosh, P. | 登録日 | 2005-02-11 | 公開日 | 2005-09-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | The C-type lectin fold as an evolutionary solution for massive sequence variation Nat.Struct.Mol.Biol., 12, 2005
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1YU0
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![BU of 1yu0 by Molmil](/molmil-images/mine/1yu0) | Major Tropism Determinant P1 Variant | 分子名称: | CALCIUM ION, Major Tropism Determinant (Mtd-P1) | 著者 | McMahon, S.A, Miller, J.L, Lawton, J.A, Ghosh, P. | 登録日 | 2005-02-11 | 公開日 | 2005-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | The C-type lectin fold as an evolutionary solution for massive sequence variation Nat.Struct.Mol.Biol., 12, 2005
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1YU2
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![BU of 1yu2 by Molmil](/molmil-images/mine/1yu2) | Major Tropism Determinant M1 Variant | 分子名称: | MAGNESIUM ION, Major Tropism Determinant (Mtd-M1) | 著者 | McMahon, S.A, Miller, J.L, Lawton, J.A, Ghosh, P. | 登録日 | 2005-02-11 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | The C-type lectin fold as an evolutionary solution for massive sequence variation Nat.Struct.Mol.Biol., 12, 2005
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1YU3
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![BU of 1yu3 by Molmil](/molmil-images/mine/1yu3) | Major Tropism Determinant I1 Variant | 分子名称: | MAGNESIUM ION, Major Tropism Determinant (Mtd-I1) | 著者 | McMahon, S.A, Miller, J.L, Lawton, J.A, Ghosh, P. | 登録日 | 2005-02-11 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | The C-type lectin fold as an evolutionary solution for massive sequence variation Nat.Struct.Mol.Biol., 12, 2005
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4CQJ
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![BU of 4cqj by Molmil](/molmil-images/mine/4cqj) | |
4AVF
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![BU of 4avf by Molmil](/molmil-images/mine/4avf) | Crystal structure of Pseudomonas aeruginosa inosine 5'-monophosphate dehydrogenase | 分子名称: | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE | 著者 | McMahon, S.A, Moynie, L, Liu, H, Duthie, F, Naismith, J.H. | 登録日 | 2012-05-25 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery Acta Crystallogr.,Sect.F, 69, 2013
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4AVR
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![BU of 4avr by Molmil](/molmil-images/mine/4avr) | Crystal structure of the hypothetical protein Pa4485 from Pseudomonas aeruginosa | 分子名称: | PA4485 | 著者 | McMahon, S.A, Moynie, L, Liu, H, Duthie, F, Alphey, M.S, Naismith, J.H. | 登録日 | 2012-05-29 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | The Aeropath Project Targeting Pseudomonas Aeruginosa: Crystallographic Studies for Assessment of Potential Targets in Early-Stage Drug Discovery. Acta Crystallogr.,Sect.F, 69, 2013
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4CCV
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![BU of 4ccv by Molmil](/molmil-images/mine/4ccv) | Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: Implications for the regulation of angiogenesis | 分子名称: | GLUTATHIONE, GLYCEROL, HISTIDINE-RICH GLYCOPROTEIN, ... | 著者 | McMahon, S.A, Kassaar, O, Stewart, A.J, Naismith, J.H. | 登録日 | 2013-10-29 | 公開日 | 2014-02-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Crystal Structure of Histidine-Rich Glycoprotein N2 Domain Reveals Redox Activity at an Interdomain Disulfide Bridge: Implications for Angiogenic Regulation. Blood, 123, 2014
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4BQQ
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2WR8
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![BU of 2wr8 by Molmil](/molmil-images/mine/2wr8) | Structure of Pyrococcus horikoshii SAM hydroxide adenosyltransferase in complex with SAH | 分子名称: | PUTATIVE UNCHARACTERIZED PROTEIN PH0463, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | McMahon, S.A, Deng, H, O'Hagan, D, Johnson, K.A, Naismith, J.H. | 登録日 | 2009-08-31 | 公開日 | 2009-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Mechanistic Insights Into Water Activation in Sam Hydroxide Adenosyltransferase (Duf-62). Chembiochem, 10, 2009
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2W82
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![BU of 2w82 by Molmil](/molmil-images/mine/2w82) | The structure of ArdA | 分子名称: | ORF18 | 著者 | McMahon, S.A, Roberts, G.A, Carter, L.G, Cooper, L.P, Liu, H, White, J.H, Johnson, K.A, Sanghvi, B, Oke, M, Walkinshaw, M.D, Blakely, G, Naismith, J.H, Dryden, D.T.F. | 登録日 | 2009-01-08 | 公開日 | 2009-01-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Extensive DNA Mimicry by the Arda Anti-Restriction Protein and its Role in the Spread of Antibiotic Resistance. Nucleic Acids Res., 37, 2009
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1I8T
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![BU of 1i8t by Molmil](/molmil-images/mine/1i8t) | STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM E.COLI | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, UDP-GALACTOPYRANOSE MUTASE | 著者 | Sanders, D.A.R, Staines, A.G, McMahon, S.A, McNeil, M.R, Whitfield, C, Naismith, J.H. | 登録日 | 2001-03-16 | 公開日 | 2001-10-03 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | UDP-galactopyranose mutase has a novel structure and mechanism. Nat.Struct.Biol., 8, 2001
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2XU2
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![BU of 2xu2 by Molmil](/molmil-images/mine/2xu2) | Crystal Structure of the hypothetical protein PA4511 from Pseudomonas aeruginosa | 分子名称: | CITRIC ACID, UPF0271 PROTEIN PA4511 | 著者 | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, McMahon, S.A, White, M.F, Naismith, J.H. | 登録日 | 2010-10-14 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genomics, 11, 2010
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2XBN
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![BU of 2xbn by Molmil](/molmil-images/mine/2xbn) | Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE | 著者 | Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J. | 登録日 | 2010-04-13 | 公開日 | 2010-05-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation. Mol.Biosystems, 6, 2010
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5FIU
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![BU of 5fiu by Molmil](/molmil-images/mine/5fiu) | Binding and structural studies of a 5,5-difluoromethyl adenosine nucleoside with the fluorinase enzyme | 分子名称: | 5'-FLUORO-5'-DEOXY-ADENOSINE SYNTHASE, 5,5-DIFLUOROMETHYL ADENOSINE, L(+)-TARTARIC ACID | 著者 | Thompson, S, McMahon, S.A, Naismith, J.H, O'Hagan, D. | 登録日 | 2015-10-02 | 公開日 | 2015-12-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Exploration of a Potential Difluoromethyl-Nucleoside Substrate with the Fluorinase Enzyme. Bioorg.Chem., 64, 2015
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6I6X
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![BU of 6i6x by Molmil](/molmil-images/mine/6i6x) | New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes | 分子名称: | (1~{R},2~{R},3~{R},4~{S},5~{S},6~{R})-7-methyl-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gloster, T.M, McMahon, S.A, Oehler, V. | 登録日 | 2018-11-15 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes. Chemistry, 24, 2018
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6I6R
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![BU of 6i6r by Molmil](/molmil-images/mine/6i6r) | New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes | 分子名称: | (1~{R},2~{R},3~{R},4~{S},6~{S})-6-azanyl-2,3,4-tris(oxidanyl)cyclohexane-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-L-iduronidase, ... | 著者 | Gloster, T.M, McMahon, S.A, Oehler, V. | 登録日 | 2018-11-15 | 公開日 | 2018-12-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes. Chemistry, 24, 2018
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8PCW
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![BU of 8pcw by Molmil](/molmil-images/mine/8pcw) | Structure of Csm6' from Streptococcus thermophilus | 分子名称: | CRISPR system endoribonuclease Csm6' | 著者 | McQuarrie, S.J, Athukoralage, J.S, McMahon, S.A, Graham, S, Ackerman, K, Bode, B.E, White, M.F, Gloster, T.M. | 登録日 | 2023-06-11 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.54 Å) | 主引用文献 | Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open. Nucleic Acids Res., 51, 2023
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8PE3
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![BU of 8pe3 by Molmil](/molmil-images/mine/8pe3) | Structure of Csm6' from Streptococcus thermophilus in complex with cyclic hexa-adenylate (cA6) | 分子名称: | CRISPR system endoribonuclease Csm6', Cyclic hexaadenosine monophosphate (cA6), RNA | 著者 | McQuarrie, S.J, Athukoralage, J.S, McMahon, S.A, Graham, S, Ackerman, K, Bode, B.E, White, M.F, Gloster, T.M. | 登録日 | 2023-06-13 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open. Nucleic Acids Res., 51, 2023
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6FI2
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![BU of 6fi2 by Molmil](/molmil-images/mine/6fi2) | VexL: A periplasmic depolymerase provides new insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid-(1-4)-3-O-acetyl-2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid-(1-4)-3-O-acetyl-2-acetamido-2-deoxy-alpha-D-galactopyranuronic acid, MALONATE ION, VexL | 著者 | Naismith, J.H, McMahon, S.A, Le Bas, A, Liston, S.D, Whitfield, C. | 登録日 | 2018-01-16 | 公開日 | 2018-05-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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