6I6X

New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes

Summary for 6I6X

• Entry DOI: 10.2210/pdb6i6x/pdb
• Related: 6I6R
• Descriptor: Alpha-L-iduronidase, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: iduronidase inhibitors gh39, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 145017.02

Authors

Gloster, T.M.,McMahon, S.A.,Oehler, V. (deposition date: 2018-11-15, release date: 2018-12-05, Last modification date: 2024-01-24)

• Primary citation: Artola, M.,Kuo, C.L.,McMahon, S.A.,Oehler, V.,Hansen, T.,van der Lienden, M.,He, X.,van den Elst, H.,Florea, B.I.,Kermode, A.R.,van der Marel, G.A.,Gloster, T.M.,Codee, J.D.C.,Overkleeft, H.S.,Aerts, J.M.F.G.; New Irreversible alpha-l-Iduronidase Inhibitors and Activity-Based Probes.; Chemistry, 24:19081-19088, 2018; PubMed: 30307091; DOI: 10.1002/chem.201804662

Experimental method

X-RAY DIFFRACTION (2.39 Å)