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PDB: 173 results

3RRT
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Structure of the RSV F protein in the post-fusion conformation
Descriptor: Fusion glycoprotein F0
Authors:McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
Deposit date:2011-04-30
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3RRR
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Structure of the RSV F protein in the post-fusion conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
Deposit date:2011-04-30
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.821 Å)
Cite:Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3U36
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Crystal Structure of PG9 Fab
Descriptor: PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
Authors:McLellan, J.S, Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
5UDD
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BU of 5udd by Molmil
Crystal Structure of RSV F B9320 Bound to MEDI8897
Descriptor: Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, MEDI8897 Fab Light Chain, ...
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5UDE
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BU of 5ude by Molmil
Crystal Structure of RSV F B9320 DS-Cav1
Descriptor: Fusion glycoprotein F0, SULFATE ION
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
5UDC
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Crystal Structure of RSV F A2 Bound to MEDI8897
Descriptor: CHLORIDE ION, Fusion glycoprotein F0, MEDI8897 Fab Heavy Chain, ...
Authors:McLellan, J.S.
Deposit date:2016-12-26
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Sci Transl Med, 9, 2017
6XKL
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BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
Deposit date:2020-06-26
Release date:2020-07-15
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
8CW9
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BU of 8cw9 by Molmil
Prefusion-stabilized hMPV fusion protein bound to ADI-61026 and MPE8 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-61026 heavy, ADI-61026 light, ...
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2022-05-18
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Potently neutralizing and protective anti-human metapneumovirus antibodies target diverse sites on the fusion glycoprotein.
Immunity, 55, 2022
4DQO
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Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
Descriptor: 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ...
Authors:Pancera, M, McLellan, J.S, Kwong, P.D.
Deposit date:2012-02-16
Release date:2013-03-06
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.438 Å)
Cite:Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.
Nat.Struct.Mol.Biol., 20, 2013
5L1X
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Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Mas, V, Melero, J.A, McLellan, J.S.
Deposit date:2016-07-29
Release date:2016-08-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.
Plos Pathog., 12, 2016
3U46
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CH04H/CH02L P212121
Descriptor: CH02 Light chain Fab, CH04 Heavy chain Fab
Authors:Louder, R, Pancera, M, McLellan, J.S, Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3V7A
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Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle
Descriptor: 5B18 heavy chain, 5B18 kappa chain, Capsid
Authors:Hansman, G.S, Mclellan, J.S, Kwong, P.D.
Deposit date:2011-12-20
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.297 Å)
Cite:Structural Basis for Broad Detection of Genogroup II Noroviruses by a Monoclonal Antibody That Binds to a Site Occluded in the Viral Particle.
J.Virol., 86, 2012
7KBB
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BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
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Crystal structure of the HCMV pentamer-specific Fab 2-18
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
8DF1
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BU of 8df1 by Molmil
Chi3l1 bound by antibody C59
Descriptor: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2022-06-21
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-06-16
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
8DCN
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BU of 8dcn by Molmil
Crystal structure of Clostridioides difficile binary toxin CDTb D4 fragment in complex with BINTOXB/9 Fab
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/9 Fab heavy chain, BINTOXB/9 Fab light chain
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-06-16
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
8DO4
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BU of 8do4 by Molmil
Prefusion-stabilized Nipah virus fusion protein, dimer of trimers
Descriptor: Fusion glycoprotein F0
Authors:Byrne, P.O, Blade, E.G, McLellan, J.S.
Deposit date:2022-07-12
Release date:2023-07-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8DNG
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BU of 8dng by Molmil
Prefusion-stabilized Nipah virus fusion protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Byrne, P.O, Blade, E.G, McLellan, J.S.
Deposit date:2022-07-11
Release date:2023-07-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8DNR
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BU of 8dnr by Molmil
Prefusion-stabilized Hendra virus fusion protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Byrne, P.O, Blade, E.G, McLellan, J.S.
Deposit date:2022-07-11
Release date:2023-07-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Prefusion stabilization of the Hendra and Langya virus F proteins.
J.Virol., 98, 2024
8DMJ
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BU of 8dmj by Molmil
Postfusion Nipah virus fusion protein in complex with Fab 1H1
Descriptor: Fusion glycoprotein F0,Fusion glycoprotein F1, antibody 1H1 heavy chain, antibody 1H1 light chain
Authors:Byrne, P.O, Blade, E.G, McLellan, J.S.
Deposit date:2022-07-08
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Postfusion Nipah virus fusion protein in complex with Fab 1H1
To Be Published
6PXG
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BU of 6pxg by Molmil
Crystal Structure of MERS-CoV neutralizing antibody G2 Fab
Descriptor: G2 Fab Heavy Chain, G2 Fab Light chain
Authors:Wang, N, McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6PXH
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BU of 6pxh by Molmil
Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIHYDROFOLIC ACID, ...
Authors:Wang, N, McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6PZK
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Cryo-EM Structure of the Respiratory Syncytial Virus Polymerase (L) Protein Bound by the Tetrameric Phosphoprotein (P)
Descriptor: Phosphoprotein, RNA-directed RNA polymerase L
Authors:Gilman, M.S.A, McLellan, J.S.
Deposit date:2019-08-01
Release date:2019-09-11
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the Respiratory Syncytial Virus Polymerase Complex.
Cell, 179, 2019
5FHA
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Crystal Structure of Protective Ebola Virus Antibody 114
Descriptor: Antibody 114 Fab heavy chain, Antibody 114 Fab light chain
Authors:Gilman, M.S.A, McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016

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