7L3N
| SARS-CoV 2 Spike Protein bound to LY-CoV555 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV555 Fab heavy chain, ... | 著者 | Goldsmith, J.A, McLellan, J.S. | 登録日 | 2020-12-18 | 公開日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection. Biorxiv, 2020
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7L7R
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7KX4
| Anti-CCHFV ADI-36121 Fab | 分子名称: | ADI-36121 Fab heavy chain, ADI-36121 Fab light chain | 著者 | Mishra, A.K, McLellan, J.S. | 登録日 | 2020-12-03 | 公開日 | 2021-12-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375, 2022
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7LVW
| Structure of RSV F in Complex with VHH Cl184 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F-VHH-Cl184, ... | 著者 | Hsieh, C.-L, McLellan, J.S. | 登録日 | 2021-02-26 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody. J.Virol., 95, 2021
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7LVU
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7LUC
| Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | 分子名称: | 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ... | 著者 | Wrapp, D, McLellan, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-04-21 | 最終更新日 | 2021-04-28 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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7LUE
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7LUD
| Crystal structure of Fab ADI-14442 | 分子名称: | ADI-14442 Fab Heavy chain, ADI-14442 Fab Light chain, SULFATE ION | 著者 | Rush, S.A, McLellan, J.S. | 登録日 | 2021-02-22 | 公開日 | 2021-06-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses. Immunity, 54, 2021
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7M1C
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7LYV
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7M22
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7LYW
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7M8J
| SARS-CoV-2 S-NTD + Fab CM25 | 分子名称: | CM25 Fab - Heavy Chain, CM25 Fab - Light Chain, Spike protein S1 | 著者 | Johnson, N.V, Mclellan, J.S. | 登録日 | 2021-03-29 | 公開日 | 2021-05-19 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes. Science, 372, 2021
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5TOJ
| Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... | 著者 | Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. | 登録日 | 2016-10-17 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
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5TP3
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5TOK
| Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-L66 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, Fibritin chimera, ... | 著者 | Gilman, M.S.A, Kabeche, S.C, McLellan, J.S. | 登録日 | 2016-10-17 | 公開日 | 2017-02-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state. Nat Commun, 8, 2017
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6APC
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6APD
| Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | 分子名称: | AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, Fusion glycoprotein F0,Envelope glycoprotein, ... | 著者 | Wrapp, D, McLellan, J.S. | 登録日 | 2017-08-17 | 公開日 | 2018-03-21 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation. Immunity, 48, 2018
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6APB
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6C6Z
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6CRV
| SARS Spike Glycoprotein, Stabilized variant, C3 symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | 著者 | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | 登録日 | 2018-03-19 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6CRZ
| SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, C3 symmetry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | 著者 | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | 登録日 | 2018-03-19 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6CS0
| SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, one S1 CTD in an upwards conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | 著者 | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | 登録日 | 2018-03-19 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6CS2
| SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | 登録日 | 2018-03-19 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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6CS1
| SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, two S1 CTDs in an upwards conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... | 著者 | Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. | 登録日 | 2018-03-19 | 公開日 | 2018-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
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