6ORR
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![BU of 6orr by Molmil](/molmil-images/mine/6orr) | Co-crystal structure of human NicotinamideN-Methyltransferase (NNMT) in complex with High-Affinity Alkynyl Bisubstrate Inhibitor NS1 | Descriptor: | 9-{9-amino-6-[(3-carbamoylphenyl)ethynyl]-5,6,7,8,9-pentadeoxy-D-glycero-alpha-L-talo-decofuranuronosyl}-9H-purin-6-amine, GLYCEROL, NNMT protein | Authors: | May, E.J, Policarpo, R.L, Gaudet, R. | Deposit date: | 2019-04-30 | Release date: | 2019-10-23 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | High-Affinity Alkynyl Bisubstrate Inhibitors of NicotinamideN-Methyltransferase (NNMT). J.Med.Chem., 62, 2019
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6XL0
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![BU of 6xl0 by Molmil](/molmil-images/mine/6xl0) | Caulobacter crescentus FljK filament | Descriptor: | Flagellin | Authors: | Montemayor, E.J, Ploscariu, N.T, Sanchez, J.C, Parrell, D, Dillard, R.S, Shebelut, C.W, Ke, Z, Guerrero-Ferreira, R.C, Wright, E.R. | Deposit date: | 2020-06-27 | Release date: | 2020-12-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Flagellar Structures from the Bacterium Caulobacter crescentus and Implications for Phage phi CbK Predation of Multiflagellin Bacteria J.Bacteriol., 203, 2021
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6XKY
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![BU of 6xky by Molmil](/molmil-images/mine/6xky) | Caulobacter crescentus FljK filament, straightened | Descriptor: | Flagellin | Authors: | Montemayor, E.J, Ploscariu, N.T, Sanchez, J.C, Parrell, D, Dillard, R.S, Shebelut, C.W, Ke, Z, Guerrero-Ferreira, R.C, Wright, E.R. | Deposit date: | 2020-06-27 | Release date: | 2020-12-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Flagellar Structures from the Bacterium Caulobacter crescentus and Implications for Phage phi CbK Predation of Multiflagellin Bacteria J.Bacteriol., 203, 2021
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4PEF
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![BU of 4pef by Molmil](/molmil-images/mine/4pef) | Dbr1 in complex with sulfate | Descriptor: | GLYCEROL, MANGANESE (II) ION, RNA lariat debranching enzyme, ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4PEH
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![BU of 4peh by Molmil](/molmil-images/mine/4peh) | Dbr1 in complex with synthetic linear RNA | Descriptor: | GLYCEROL, MANGANESE (II) ION, RNA (5'-R(*CP*UP*AP*(A2P)P*AP*CP*AP*A)-3'), ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4PEI
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![BU of 4pei by Molmil](/molmil-images/mine/4pei) | Dbr1 in complex with synthetic branched RNA analog | Descriptor: | GLYCEROL, NICKEL (II) ION, RNA (5'-R(*(G46)P*U)-3'), ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4PEG
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![BU of 4peg by Molmil](/molmil-images/mine/4peg) | Dbr1 in complex with guanosine-5'-monophosphate | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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6PPN
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![BU of 6ppn by Molmil](/molmil-images/mine/6ppn) | Structure of S. pombe Lsm2-8 with unprocessed U6 snRNA | Descriptor: | Mimic of unprocessed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-07-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
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6PPQ
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![BU of 6ppq by Molmil](/molmil-images/mine/6ppq) | |
6PPV
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![BU of 6ppv by Molmil](/molmil-images/mine/6ppv) | |
6PPP
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![BU of 6ppp by Molmil](/molmil-images/mine/6ppp) | Structure of S. pombe Lsm2-8 with processed U6 snRNA | Descriptor: | Mimic of processed U6 snRNA, Probable U6 snRNA-associated Sm-like protein LSm3, Probable U6 snRNA-associated Sm-like protein LSm4, ... | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-07-08 | Release date: | 2020-06-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Rna, 26, 2020
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4N0T
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![BU of 4n0t by Molmil](/molmil-images/mine/4n0t) | Core structure of the U6 small nuclear ribonucleoprotein at 1.7 Angstrom resolution | Descriptor: | SULFATE ION, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA | Authors: | Montemayor, E.J, Curran, E.C, Liao, H, Andrews, K.L, Treba, C.N, Butcher, S.E, Brow, D.A. | Deposit date: | 2013-10-02 | Release date: | 2014-05-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution. Nat.Struct.Mol.Biol., 21, 2014
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6E7L
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![BU of 6e7l by Molmil](/molmil-images/mine/6e7l) | Structure of a dimerized UUCG motif | Descriptor: | RNA (5'-R(*GP*GP*GP*CP*UP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*UP*GP*CP*CP*C)-3') | Authors: | Montemayor, E.J, Butcher, S.E. | Deposit date: | 2018-07-26 | Release date: | 2019-07-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking. Acta Crystallogr.,Sect.F, 75, 2019
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5TF6
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![BU of 5tf6 by Molmil](/molmil-images/mine/5tf6) | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core | Descriptor: | CHLORIDE ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2016-09-24 | Release date: | 2017-01-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core. Acta Crystallogr D Struct Biol, 73, 2017
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3BJ7
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![BU of 3bj7 by Molmil](/molmil-images/mine/3bj7) | |
6ASO
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![BU of 6aso by Molmil](/molmil-images/mine/6aso) | Structure of yeast U6 snRNP with 3'-phosphate terminated U6 RNA | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Montemayor, E.J, Brow, D.A, Butcher, S.E. | Deposit date: | 2017-08-25 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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3BJ8
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![BU of 3bj8 by Molmil](/molmil-images/mine/3bj8) | |
5V1M
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![BU of 5v1m by Molmil](/molmil-images/mine/5v1m) | Structure of human Usb1 with uridine 5'-monophosphate | Descriptor: | CHLORIDE ION, GLYCEROL, U6 snRNA phosphodiesterase, ... | Authors: | Montemayor, E.J, Didychuk, A.L, Butcher, S.E. | Deposit date: | 2017-03-02 | Release date: | 2017-08-16 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Usb1 controls U6 snRNP assembly through evolutionarily divergent cyclic phosphodiesterase activities. Nat Commun, 8, 2017
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5VSU
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![BU of 5vsu by Molmil](/molmil-images/mine/5vsu) | Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA | Descriptor: | Saccharomyces cerevisiae strain T8 chromosome XII sequence, U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA-associated Sm-like protein LSm2, ... | Authors: | Montemayor, E.J. | Deposit date: | 2017-05-12 | Release date: | 2018-05-09 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA. Nat Commun, 9, 2018
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2N7M
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![BU of 2n7m by Molmil](/molmil-images/mine/2n7m) | NMR-SAXS/WAXS Structure of the core of the U4/U6 di-snRNA | Descriptor: | RNA (92-MER) | Authors: | Cornilescu, G, Didychuk, A.L, Rodgers, M.L, Michael, L.A, Burke, J.E, Montemayor, E.J, Hoskins, A.A, Butcher, S.E, Tonelli, M. | Deposit date: | 2015-09-14 | Release date: | 2015-12-30 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Analysis of Multi-Helical RNAs by NMR-SAXS/WAXS: Application to the U4/U6 di-snRNA. J.Mol.Biol., 428, 2016
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6PFQ
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6PGL
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![BU of 6pgl by Molmil](/molmil-images/mine/6pgl) | Structure of Kluyveromyces marxianus Usb1 with uridine monophosphate | Descriptor: | 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, GLYCEROL, ... | Authors: | Nomura, Y, Montemayor, E.J, Butcher, S.E. | Deposit date: | 2019-06-24 | Release date: | 2019-12-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.845 Å) | Cite: | Structural basis for the evolution of cyclic phosphodiesterase activity in the U6 snRNA exoribonuclease Usb1. Nucleic Acids Res., 48, 2020
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8UXJ
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![BU of 8uxj by Molmil](/molmil-images/mine/8uxj) | Caulobacter crescentus FljK flagellar filament (asymmetrical) | Descriptor: | Flagellin FljK | Authors: | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | Deposit date: | 2023-11-09 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization To Be Published
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8UXN
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![BU of 8uxn by Molmil](/molmil-images/mine/8uxn) | Caulobacter crescentus FljM flagellar filament (symmetrized) | Descriptor: | Flagellin FljM | Authors: | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | Deposit date: | 2023-11-09 | Release date: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.11 Å) | Cite: | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
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8UXK
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![BU of 8uxk by Molmil](/molmil-images/mine/8uxk) | Caulobacter crescentus FljL flagellar filament (asymmetrical) | Descriptor: | Flagellin | Authors: | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | Deposit date: | 2023-11-09 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
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