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PDB: 5 results

1M1L
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BU of 1m1l by Molmil
Human Suppressor of Fused (N-terminal domain)
Descriptor: Suppressor of Fused
Authors:Merchant, M, Vajdos, F.F, Ultsch, M, Maun, H.R, Wendt, U, Cannon, J, Lazarus, R.A, de Vos, A.M, de Sauvage, F.J.
Deposit date:2002-06-19
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Suppressor of fused regulates Gli activity through a dual binding mechanism
Mol.Cell.Biol., 24, 2004
5WI6
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BU of 5wi6 by Molmil
Human beta-1 tryptase mutant Ile99Cys
Descriptor: L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, SULFATE ION, Tryptase alpha/beta-1
Authors:Eigenbrot, C, Maun, H.R.
Deposit date:2017-07-18
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Dual functionality of beta-tryptase protomers as both proteases and cofactors in the active tetramer.
J. Biol. Chem., 293, 2018
1SI5
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BU of 1si5 by Molmil
Protease-like domain from 2-chain hepatocyte growth factor
Descriptor: hepatocyte growth factor
Authors:Kirchhofer, D, Yao, X, Peek, M, Eigenbrot, C, Lipari, M.T, Billeci, K.L, Maun, H.R, Moran, P, Santell, L, Lazarus, R.A.
Deposit date:2004-02-27
Release date:2004-12-28
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling
J.Biol.Chem., 279, 2004
3MXV
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Crystal structure of fab fragment of anti-Shh 5E1 chimera
Descriptor: SULFATE ION, fab fragment of anti-Shh 5E1 mouse/human chimera, heavy chain, ...
Authors:Hymowitz, S.G, Maun, H.R.
Deposit date:2010-05-07
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site.
J.Biol.Chem., 285, 2010
3MXW
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BU of 3mxw by Molmil
Crystal structure Sonic hedgehog bound to the 5E1 fab fragment
Descriptor: 5E1 heavy chain, 5E1 light chain, CALCIUM ION, ...
Authors:Hymowitz, S.G, Maun, H.R.
Deposit date:2010-05-07
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Hedgehog pathway antagonist 5E1 binds hedgehog at the pseudo-active site.
J.Biol.Chem., 285, 2010

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