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PDB: 287 件

8FNK
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Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
分子名称: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FN6
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Cryo-EM structure of RNase-untreated RESC-A in trypanosomal RNA editing
分子名称: ADENOSINE-5'-TRIPHOSPHATE, RNA-editing substrate-binding complex protein 1 (RESC1), RNA-editing substrate-binding complex protein 2 (RESC2), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
1UH6
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Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
分子名称: ubiquitin-like 5
著者Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-06-25
公開日2003-12-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
To be Published
1UHS
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Solution structure of mouse homeodomain-only protein HOP
分子名称: homeodomain only protein
著者Saito, K, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-10
公開日2004-07-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of mouse homeodomain-only protein HOP
To be Published
1UHR
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Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
分子名称: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily D member 1
著者Yamada, K, Saito, K, Nameki, N, Inoue, M, Koshiba, S, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-09
公開日2004-08-24
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
To be Published
1UHT
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Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein
分子名称: expressed protein
著者Tomizawa, T, Inoue, M, Koshiba, S, Hayashi, F, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Shinozaki, K, Seki, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-07-10
公開日2004-01-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein
To be Published
5B2M
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A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
分子名称: Dual specificity mitogen-activated protein kinase kinase 7
著者Sogabe, Y, Hashimoto, T, Matsumoto, T, Kirii, Y, Sawa, M, Kinoshita, T.
登録日2016-01-19
公開日2016-04-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Biochem.Biophys.Res.Commun., 473, 2016
6JUX
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Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-71807
分子名称: 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{N}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine, Activin receptor type-1, SULFATE ION
著者Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M.
登録日2019-04-15
公開日2020-04-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis of Activin Receptor-Like Kinase 2 (R206H) Inhibition by Bis-heteroaryl Pyrazole-Based Inhibitors for the Treatment of Fibrodysplasia Ossificans Progressiva Identified by the Integration of Ligand-Based and Structure-Based Drug Design Approaches.
Acs Omega, 5, 2020
5B2K
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A crucial role of Cys218 in the stabilization of an unprecedented auto-inhibition form of MAP2K7
分子名称: Dual specificity mitogen-activated protein kinase kinase 7
著者Sogabe, Y, Hashimoto, T, Matsumoto, T, Kirii, Y, Sawa, M, Kinoshita, T.
登録日2016-01-19
公開日2016-04-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Biochem.Biophys.Res.Commun., 473, 2016
7WAC
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Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1)
分子名称: Cyanophycin synthase
著者Kawasaki, M, Miyakawa, T, Yang, J, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M.
登録日2021-12-14
公開日2022-09-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase.
Nat Commun, 13, 2022
7WAD
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Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS
分子名称: Cyanophycin synthase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
著者Kawasaki, M, Miyakawa, T, Yang, J, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M.
登録日2021-12-14
公開日2022-09-07
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase.
Nat Commun, 13, 2022
6KJG
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Crystal structure of PsoF
分子名称: Dual-functional monooxygenase/methyltransferase psoF
著者Hara, K, Hashimoto, H, Matsushita, T, Tsunematsu, Y, Watanabe, K.
登録日2019-07-22
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Functional and Structural Analyses oftrans C-Methyltransferase in Fungal Polyketide Biosynthesis.
Biochemistry, 58, 2019
1WRB
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Crystal structure of the N-terminal RecA-like domain of DjVLGB, a pranarian Vasa-like RNA helicase
分子名称: DjVLGB, SULFATE ION
著者Kurimoto, K, Muto, Y, Obayashi, N, Terada, T, Shirouzu, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Kigawa, T, Okumura, H, Tanaka, A, Shibata, N, Kashikawa, M, Agata, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-10-14
公開日2005-04-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B protein
J.Struct.Biol., 150, 2005
6J1C
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Photoswitchable fluorescent protein Gamillus, N150C/T204V double mutant, off-state
分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein
著者Nakashima, R, Shinoda, H, Matsuda, T, Nagai, T.
登録日2018-12-28
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol, 26, 2019
6J1B
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Photoswitchable fluorescent protein Gamillus, N150C/T204V double mutant, on-state
分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein, ...
著者Nakashima, R, Shinoda, H, Matsuda, T, Nagai, T.
登録日2018-12-28
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol, 26, 2019
6J1A
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Photoswitchable fluorescent protein Gamillus, off-state
分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein, ...
著者Nakashima, R, Sakurai, K, shinoda, H, Matsuda, T, Nagai, T.
登録日2018-12-28
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol, 26, 2019
5Y90
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MAP2K7 mutant -C218S
分子名称: Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL
著者Kinoshita, T, Hashimoto, T, Sogabe, Y, Matsumoto, T, Sawa, M, Fukada, H.
登録日2017-08-22
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7
Biochem. Biophys. Res. Commun., 493, 2017
6JXF
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Photoswitchable fluorescent protein Gamillus, off-state (pH7.0)
分子名称: CHLORIDE ION, GLYCEROL, Green fluorescent protein, ...
著者Nakashima, R, Sakurai, K, shinoda, H, Matsuda, T, Nagai, T.
登録日2019-04-23
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol, 26, 2019
1MKC
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C-TERMINAL DOMAIN OF MIDKINE
分子名称: PROTEIN (MIDKINE)
著者Iwasaki, W, Nagata, K, Hatanaka, H, Ogura, K, Inui, T, Kimura, T, Muramatsu, T, Yoshida, K, Tasumi, M, Inagaki, F.
登録日1999-03-16
公開日1999-03-23
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of midkine, a new heparin-binding growth factor.
EMBO J., 16, 1997
5B0D
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Polyketide cyclase OAC from Cannabis sativa, Y27W mutant
分子名称: Olivetolic acid cyclase
著者Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H.
登録日2015-10-28
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa
Febs J., 283, 2016
5B0E
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Polyketide cyclase OAC from Cannabis sativa, V59M mutant
分子名称: GLYCEROL, Olivetolic acid cyclase
著者Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H.
登録日2015-10-28
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa
Febs J., 283, 2016
6ACR
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Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638
分子名称: Activin receptor type-1, N-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine, SULFATE ION
著者Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M.
登録日2018-07-27
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H).
Chem. Pharm. Bull., 67, 2019
7CAO
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Crystal structure of red chromoprotein from Olindias formosa
分子名称: Chromoprotein
著者Nakashima, R, Zhai, L, Ike, Y, Matsudz, T, Nagai, T.
登録日2020-06-09
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure-based analysis and evolution of a monomerized red-colored chromoprotein from the Olindias formosa jellyfish.
Protein Sci., 31, 2022
5B0F
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Polyketide cyclase OAC from Cannabis sativa, Y72F mutant
分子名称: GLYCEROL, Olivetolic acid cyclase
著者Yang, X, Matsui, T, Mori, T, Abe, I, Morita, H.
登録日2015-10-28
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for olivetolic acid formation by a polyketide cyclase from Cannabis sativa
Febs J., 283, 2016
3W0T
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Human Glyoxalase I with an N-hydroxypyridone derivative inhibitor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lactoylglutathione lyase, N-[3-(1-hydroxy-6-oxo-4-phenyl-1,6-dihydropyridin-2-yl)phenyl]methanesulfonamide, ...
著者Fukami, T.A, Irie, M, Matsuura, T.
登録日2012-11-02
公開日2013-11-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献N-Hydroxypyridone-based glyoxalase I inhibitors mimicking binding interactions of the substrate
To be Published

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