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PDB: 55 件
5JR1
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Crystal structure of 10E8 gHV-matureL antigen-binding fragment.
分子名称: 10E8 heavy chain, 10E8 mature light chain, ZINC ION
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-05
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.
Plos One, 11, 2016
6C6Y
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BU of 6c6y by Molmil
Crystal structure of Middle-East Respiratory Syndrome (MERS) coronavirus neutralizing antibody JC57-14 isolated from a vaccinated rhesus macaque in complex with MERS Receptor Binding Domain
分子名称: JC57-14 Heavy chain, JC57-14 Light chain, SULFATE ION, ...
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2018-01-19
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
5K6B
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BU of 5k6b by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9 DS-Cav1 variant.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Zhang, B, Rundlet, E.J, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.981 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6G
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BU of 5k6g by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-24 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5JOF
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BU of 5jof by Molmil
Crystal structure of VRC03 gHVgLV antigen-binding fragment.
分子名称: SULFATE ION, VRC03 gHV heavy chain, VRC03 gLV light chain
著者Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-02
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.208 Å)
主引用文献Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
5JXA
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BU of 5jxa by Molmil
Crystal structure of ligand-free VRC03 antigen-binding fragment.
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, PHOSPHATE ION, ...
著者Zhou, T, Moquin, S, Joyce, M.G, Mascola, J.R, Kwong, P.D.
登録日2016-05-12
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.
Structure, 24, 2016
5K6F
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BU of 5k6f by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-19 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-08-10
最終更新日2016-09-21
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6C
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BU of 5k6c by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 variant.
分子名称: Fusion glycoprotein F0,Fusion glycoprotein F0, SULFATE ION
著者Joyce, M.G, Zhang, B, Lai, Y.T, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-10-12
最終更新日2016-10-19
実験手法X-RAY DIFFRACTION (3.576 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6H
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BU of 5k6h by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C variant.
分子名称: Fusion glycoprotein F0
著者Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-09-21
実験手法X-RAY DIFFRACTION (2.648 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
5K6I
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BU of 5k6i by Molmil
Crystal structure of prefusion-stabilized RSV F single-chain 9-10 DS-Cav1 A149C-Y458C, S46G-E92D-S215P-K465Q variant.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ...
著者Joyce, M.G, Zhang, B, Mascola, J.R, Kwong, P.D.
登録日2016-05-24
公開日2016-08-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.
Nat.Struct.Mol.Biol., 23, 2016
4OCW
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BU of 4ocw by Molmil
Crystal structure of human Fab CAP256-VRC26.06, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.06 heavy chain, CAP256-VRC26.06 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4ORG
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BU of 4org by Molmil
Crystal structure of human Fab CAP256-VRC26.04, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.04 heavy chain, CAP256-VRC26.04 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-02-11
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.121 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OD1
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BU of 4od1 by Molmil
Crystal structure of human Fab CAP256-VRC26.03, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.03 heavy chain, CAP256-VRC26.03 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4Q6I
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BU of 4q6i by Molmil
Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4
分子名称: Heavy chain of murine 2D5 Fab, Light chain of murine 2D5 Fab, T-cell surface glycoprotein CD4
著者Boyington, J.C, Nabel, G.J, Mascola, J.R.
登録日2014-04-22
公開日2014-07-23
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor.
Sci Transl Med, 6, 2014
4ODH
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BU of 4odh by Molmil
Crystal structure of human Fab CAP256-VRC26.UCA, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.UCA heavy chain, CAP256-VRC26.UCA light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-10
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.894 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OD3
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BU of 4od3 by Molmil
Crystal structure of human Fab CAP256-VRC26.07, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CAP256-VRC26.07 heavy chain, CAP256-VRC26.07 light chain, ...
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.616 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCS
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BU of 4ocs by Molmil
Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
4OCR
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BU of 4ocr by Molmil
Crystal structure of human Fab CAP256-VRC26.01, a potent V1V2-directed HIV-1 neutralizing antibody
分子名称: CAP256-VRC26.01 heavy chain, CAP256-VRC26.01 light chain
著者Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D.
登録日2014-01-09
公開日2014-02-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Nature, 509, 2014
3RJQ
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BU of 3rjq by Molmil
Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-04-15
公開日2012-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3R0M
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BU of 3r0m by Molmil
Crystal structure of anti-HIV llama VHH antibody A12
分子名称: Llama VHH A12, SULFATE ION
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-03-08
公開日2012-03-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
7JKS
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BU of 7jks by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
7JKT
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BU of 7jkt by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core from strain d45-01dG5, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
4Q2Z
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BU of 4q2z by Molmil
Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate
分子名称: Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody
著者Navis, M, Tran, K, Bale, S, Phad, G, Guenaga, J, Wilson, R, Soldemo, M, McKee, K, Sundling, C, Mascola, J, Li, Y, Wyatt, R.T, Hedestam, G.B.K.
登録日2014-04-10
公開日2014-09-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
Plos Pathog., 10, 2014
5WCC
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BU of 5wcc by Molmil
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab.
分子名称: GLYCEROL, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ...
著者Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D.
登録日2017-06-29
公開日2017-12-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.461 Å)
主引用文献Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.
Sci Immunol, 2, 2017
5TY6
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BU of 5ty6 by Molmil
Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 13-1b02 Fab.
分子名称: GLYCEROL, VRC 315 13-1b02 Fab Heavy chain, VRC 315 13-1b02 Fab Light chain
著者Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D.
登録日2016-11-18
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.361 Å)
主引用文献Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans.
Sci Immunol, 2, 2017

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