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PDB: 420 件

5DJV
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Crystal structure of human FPPS in complex with biaryl compound 8e
分子名称: 8-(naphthalen-1-yl)-6-(1H-pyrrol-2-yl)quinoline-2-carboxylic acid, Farnesyl pyrophosphate synthase
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-10-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
5DJR
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Crystal structure of human FPPS in complex with biaryl compound 6
分子名称: 1H,1'H-4,4'-biindole-2-carboxylic acid, Farnesyl pyrophosphate synthase, GLYCEROL, ...
著者Rondeau, J.M, Bourgier, E, Lehmann, S.
登録日2015-09-02
公開日2015-09-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
Chemmedchem, 10, 2015
1JHH
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LEXA S119A MUTANT
分子名称: LEXA REPRESSOR, SULFATE ION
著者Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J.
登録日2001-06-27
公開日2001-09-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
1W1F
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SH3 DOMAIN OF HUMAN LYN TYROSINE KINASE
分子名称: TYROSINE-PROTEIN KINASE LYN
著者Bauer, F, Schweimer, K, Hoffmann, S, Roesch, P, Sticht, H.
登録日2004-06-17
公開日2005-07-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of Lyn-SH3 Domain in Complex with a Herpesviral Protein Reveals an Extended Recognition Motif that Enhances Binding Affinity.
Protein Sci., 14, 2005
4J7Z
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Thermus thermophilus DNAJ J- and G/F-DOMAINS
分子名称: Chaperone protein DnaJ 2, GLYCEROL
著者Barends, T.R.M, Brosi, R.W, Steinmetz, A, Scherer, A, Hartmann, E, Eschenbach, J, Lorenz, T, Seidel, R, Shoeman, R, Zimmermann, S, Bittl, R, Schlichting, I, Reinstein, J.
登録日2013-02-14
公開日2013-07-31
最終更新日2024-02-28
実験手法EPR (1.64 Å), X-RAY DIFFRACTION
主引用文献Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
7QEN
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S.c. Condensin core in DNA- and ATP-bound state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Condensin complex subunit 1, Condensin complex subunit 2, ...
著者Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
登録日2021-12-03
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
7QFW
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S.c. Condensin peripheral Ycg1 subcomplex bound to DNA
分子名称: Condensin complex subunit 2, Condensin complex subunit 3, Synthetic DNA ligand, ...
著者Lecomte, L, Hassler, M, Haering, C, Eustermann, S.
登録日2021-12-06
公開日2022-06-15
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献A hold-and-feed mechanism drives directional DNA loop extrusion by condensin.
Science, 376, 2022
1JS5
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Solution Structure of dAAUAA DNA Bulge
分子名称: 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3'
著者Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H.
登録日2001-08-16
公開日2002-08-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
5CVS
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GlgE isoform 1 from Streptomyces coelicolor E423A mutant soaked in maltoheptaose
分子名称: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Rashid, A.M, Syson, K, Koliwer-Brandl, H, van de Weerd, R, Stevenson, C.E.M, Batey, S.F.D, Miah, F, Alber, M, Ioerger, T.R, Chandra, G, Appelmelk, B.J, Nartowski, K.P, Khimyak, Y.Z, Lawson, D.M, Jacobs, W.R, Geurtsen, J, Kalscheuer, R, Bornemann, S.
登録日2015-07-27
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ligand-bound structures and site-directed mutagenesis identify the acceptor and secondary binding sites of Streptomyces coelicolor maltosyltransferase GlgE.
J.Biol.Chem., 291, 2016
4J80
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Thermus thermophilus DnaJ
分子名称: Chaperone protein DnaJ 2
著者Barends, T.R.M, Brosi, R.W, Steinmetz, A, Scherer, A, Hartmann, E, Eschenbach, J, Lorenz, T, Seidel, R, Shoeman, R, Zimmermann, S, Bittl, R, Schlichting, I, Reinstein, J.
登録日2013-02-14
公開日2013-07-31
最終更新日2013-10-09
実験手法EPR (2.9 Å), X-RAY DIFFRACTION
主引用文献Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ.
Acta Crystallogr.,Sect.D, 69, 2013
1JRW
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BU of 1jrw by Molmil
Solution Structure of dAATAA DNA Bulge
分子名称: 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3'
著者Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H.
登録日2001-08-15
公開日2002-08-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
1JRV
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SOLUTION STRUCTURE OF DAATAA DNA BULGE
分子名称: 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*TP*AP*AP*GP*CP*TP*AP*CP*G)-3'
著者Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H.
登録日2001-08-15
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
1JS7
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BU of 1js7 by Molmil
Solution Structure of dAAUAA DNA Bulge
分子名称: 5'-D(*CP*GP*TP*AP*GP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*TP*CP*GP*AP*AP*UP*AP*AP*GP*CP*TP*AP*CP*G)-3'
著者Gollmick, F.A, Lorenz, M, Dornberger, U, von Langen, J, Diekmann, S, Fritzsche, H.
登録日2001-08-16
公開日2002-06-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of dAATAA and dAAUAA DNA bulges.
Nucleic Acids Res., 30, 2002
1JHC
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BU of 1jhc by Molmil
LEXA S119A C-TERMINAL TRYPTIC FRAGMENT
分子名称: LEXA REPRESSOR
著者Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J.
登録日2001-06-27
公開日2001-09-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
1JHE
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LEXA L89P Q92W E152A K156A MUTANT
分子名称: LEXA REPRESSOR
著者Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, J Strynadka, N.C.
登録日2001-06-27
公開日2001-09-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of LexA: a conformational switch for regulation of self-cleavage.
Cell(Cambridge,Mass.), 106, 2001
2KQC
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BU of 2kqc by Molmil
Second PBZ domain of human APLF protein
分子名称: Aprataxin and PNK-like factor, ZINC ION
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2KQB
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BU of 2kqb by Molmil
First PBZ domain of human APLF protein
分子名称: Aprataxin and PNK-like factor, ZINC ION
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2KQD
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BU of 2kqd by Molmil
First PBZ domain of human APLF protein in complex with ribofuranosyladenosine
分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ...
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
2KQE
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BU of 2kqe by Molmil
Second PBZ domain of human APLF protein in complex with ribofuranosyladenosine
分子名称: ADENOSINE, Aprataxin and PNK-like factor, ZINC ION, ...
著者Neuhaus, D, Eustermann, S, Brockmann, C, Yang, J.
登録日2009-11-04
公開日2010-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Nat.Struct.Mol.Biol., 17, 2010
6XZF
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Nanobody in complex with eGFP
分子名称: Nanobody targeted against eGFP, TERBIUM(III) ION, eGFP
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-02-04
公開日2021-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
6XYF
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Nanobody 22
分子名称: Nanobody 22, SODIUM ION
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-01-30
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.11097 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
6XYM
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BU of 6xym by Molmil
Nbe-LBM
分子名称: Nbe-LBM, TERBIUM(III) ION
著者Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日2020-01-30
公開日2021-02-10
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Engineered nanobodies with a lanthanide binding motif for crystallographic phasing
To Be Published
3HGM
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BU of 3hgm by Molmil
Universal Stress Protein TeaD from the TRAP transporter TeaABC of Halomonas elongata
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Universal Stress Protein TeaD
著者Schweikhard, E.S, Kuhlmann, S.I, Ziegler, C.M.
登録日2009-05-14
公開日2010-03-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of the universal stress protein TeaD and its role in regulating the ectoine transporter TeaABC of Halomonas elongata DSM 2581(T)
Biochemistry, 49, 2010
8CAV
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BU of 8cav by Molmil
Discovery of the lanthipeptide Curvocidin and structural insights into its trifunctional synthetase CuvL
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CuvA, MAGNESIUM ION, ...
著者Sigurdsson, A, Martins, B.M, Duettmann, S.A, Jasyk, M, Dimos-Roehl, B, Schoepf, F, Gemannter, M, Knittel, C.H, Schnegotyzki, R, Schmid, B, Kosol, S, Gonzalez-Viegas, M, Seidel, M, Huegelland, M, Leimkuehler, S, Dobbek, H, Mainz, A, Suessmuth, R.
登録日2023-01-24
公開日2023-06-14
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Angew.Chem.Int.Ed.Engl., 62, 2023
8CLJ
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BU of 8clj by Molmil
TFIIIC TauB-DNA dimer
分子名称: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ...
著者Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W.
登録日2023-02-16
公開日2023-06-21
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023

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件を2024-07-31に公開中

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