7QGN
 
 | | Structure of the SmrB-bound E. coli disome - stalled 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | | Deposit date: | 2021-12-09 | | Release date: | 2022-04-27 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.37 Å) | | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
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7QGR
 | | Structure of the SmrB-bound E. coli disome - collided 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Kratzat, H, Buschauer, R, Berninghausen, O, Beckmann, R. | | Deposit date: | 2021-12-09 | | Release date: | 2022-06-22 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
Nature, 603, 2022
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5JCS
 | | CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E. | | Deposit date: | 2016-04-15 | | Release date: | 2016-11-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Nat.Struct.Mol.Biol., 23, 2016
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5J8H
 | | Structure of calmodulin in a complex with a peptide derived from a calmodulin-dependent kinase | | Descriptor: | CALCIUM ION, Calmodulin, Eukaryotic elongation factor 2 kinase | | Authors: | Alphonse, S, Lee, K, Piserchio, A, Tavares, C.D.J, Giles, D.H, Wellmann, R.M, Dalby, K.N, Ghose, R. | | Deposit date: | 2016-04-07 | | Release date: | 2016-09-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin.
Structure, 24, 2016
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7OQE
 | | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... | | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2021-06-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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7OQB
 | | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | Descriptor: | ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... | | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2021-06-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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7OQC
 | | The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ... | | Authors: | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | Deposit date: | 2021-06-03 | | Release date: | 2021-08-11 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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3PIV
 | | Zebrafish interferon 1 | | Descriptor: | Interferon, NICKEL (II) ION | | Authors: | Hamming, O.J, Hartmann, R, Lutfalla, G, Levraud, J.-P. | | Deposit date: | 2010-11-08 | | Release date: | 2011-07-20 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.086 Å) | | Cite: | Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
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3SIU
 | | Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, monomeric form | | Descriptor: | NHP2-like protein 1, SULFATE ION, U4/U6 small nuclear ribonucleoprotein Prp31, ... | | Authors: | Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. | | Deposit date: | 2011-06-20 | | Release date: | 2011-08-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.626 Å) | | Cite: | Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Rna, 17, 2011
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1SYX
 | | The crystal structure of a binary U5 snRNP complex | | Descriptor: | CD2 antigen cytoplasmic tail-binding protein 2, Spliceosomal U5 snRNP-specific 15 kDa protein | | Authors: | Nielsen, T.K, Liu, S, Luhrmann, R, Ficner, R. | | Deposit date: | 2004-04-02 | | Release date: | 2005-10-18 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.345 Å) | | Cite: | Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2).
J.Mol.Biol., 369, 2007
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3SEM
 | | SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR | | Descriptor: | SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR | | Authors: | Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. | | Deposit date: | 1998-11-02 | | Release date: | 1999-01-06 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Science, 282, 1998
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3SIV
 | | Structure of a hPrp31-15.5K-U4atac 5' stem loop complex, dimeric form | | Descriptor: | NHP2-like protein 1, U4/U6 small nuclear ribonucleoprotein Prp31, U4atac snRNA | | Authors: | Liu, S, Ghalei, H, Luhrmann, R, Wahl, M.C. | | Deposit date: | 2011-06-20 | | Release date: | 2011-08-10 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.304 Å) | | Cite: | Structural basis for the dual U4 and U4atac snRNA-binding specificity of spliceosomal protein hPrp31.
Rna, 17, 2011
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7P3K
 | | Cryo-EM structure of 70S ribosome stalled with TnaC peptide (control) | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Buschauer, R, Komar, T, Becker, T, Berninghausen, O, Cheng, J, Beckmann, R. | | Deposit date: | 2021-07-08 | | Release date: | 2021-10-27 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
Nucleic Acids Res., 49, 2021
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3GKW
 | | Crystal structure of the Fab fragment of Nimotuzumab. An anti-epidermal growth factor receptor antibody | | Descriptor: | DI(HYDROXYETHYL)ETHER, Heavy chain of the antibody Nimotuzumab, Light chain of the antibody Nimotuzumab, ... | | Authors: | Talavera, A, Friemann, R, Martinez-Fleites, C, Moreno, E, Krengel, U. | | Deposit date: | 2009-03-11 | | Release date: | 2009-08-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation
Cancer Res., 69, 2009
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5CD7
 | | Crystal structure of the NTD L199M of Drosophila Oskar protein | | Descriptor: | GLYCEROL, Maternal effect protein oskar | | Authors: | Yang, N, Hu, M, Yu, Z, Wang, M, Lehmann, R, Xu, R.M. | | Deposit date: | 2015-07-03 | | Release date: | 2015-09-02 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
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7OZS
 | | Structure of the hexameric 5S RNP from C. thermophilum | | Descriptor: | 5S rRNA, 60S ribosomal protein l5-like protein, Putative ribosomal protein, ... | | Authors: | Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E. | | Deposit date: | 2021-06-28 | | Release date: | 2022-10-12 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 2023
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3HEQ
 | | Human prion protein variant D178N with M129 | | Descriptor: | CADMIUM ION, Major prion protein | | Authors: | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | Deposit date: | 2009-05-10 | | Release date: | 2010-01-12 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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5CD8
 | | Crystal structure of the NTD of Drosophila Oskar protein | | Descriptor: | GLYCEROL, Maternal effect protein oskar | | Authors: | Yang, N, Hu, M, Yu, Z, Wang, M, Lehmann, R, Xu, R.M. | | Deposit date: | 2015-07-03 | | Release date: | 2015-09-02 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
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3HES
 | | Human prion protein variant F198S with M129 | | Descriptor: | CADMIUM ION, Major prion protein | | Authors: | Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C. | | Deposit date: | 2009-05-10 | | Release date: | 2010-01-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
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5CD9
 | | Crystal structure of the CTD of Drosophila Oskar protein | | Descriptor: | Maternal effect protein oskar, SULFATE ION | | Authors: | Yang, N, Hu, M, Yu, Z, Wang, M, Lehmann, R, Xu, R.M. | | Deposit date: | 2015-07-03 | | Release date: | 2015-09-02 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structure of Drosophila Oskar reveals a novel RNA binding protein
Proc.Natl.Acad.Sci.USA, 112, 2015
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6YLE
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6HG6
 | | Clostridium beijerinckii aldo-keto reductase Cbei_3974 with NADPH | | Descriptor: | 1,2-ETHANEDIOL, L-glyceraldehyde 3-phosphate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Scott, A.F, Cresser-Brown, J, Rizkallah, P.J, Jin, Y, Allemann, R.K. | | Deposit date: | 2018-08-22 | | Release date: | 2019-05-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal Structure and Biophysical Analysis of Furfural-Detoxifying Aldehyde Reductase from Clostridium beijerinckii.
Appl.Environ.Microbiol., 85, 2019
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6YLF
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6I20
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... | | Authors: | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | Deposit date: | 2018-10-31 | | Release date: | 2019-05-29 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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3IM1
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