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PDB: 1322 件

6R1W
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 16b
分子名称: (4-azanylcyclohexyl)methyl ~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamate, Cereblon isoform 4, PHOSPHATE ION, ...
著者Heim, C, Hartmann, M.D.
登録日2019-03-15
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1C
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 12a
分子名称: 4-[[4-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyloxymethyl]phenyl]methylamino]-4-oxidanylidene-butanoic acid, ASPARTIC ACID, CHLORIDE ION, ...
著者Heim, C, Hartmann, M.D.
登録日2019-03-14
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
1ZK5
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Escherichia coli F17fG lectin domain complex with N-acetylglucosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F17G adhesin subunit
著者Buts, L, Wellens, A, Van Molle, I, De Genst, E, Wyns, L, Loris, R, Lahmann, M, Oscarson, S, De Greve, H, Bouckaert, J.
登録日2005-05-02
公開日2006-05-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Impact of natural variation in bacterial F17G adhesins on crystallization behaviour.
Acta Crystallogr.,Sect.D, 61, 2005
1FOU
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CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29
分子名称: UPPER COLLAR PROTEIN
著者Simpson, A.A, Tao, Y, Leiman, P.G, Badasso, M.O, He, Y, Jardine, P.J, Olson, N.H, Morais, M.C, Grimes, S.N, Anderson, D.L, Baker, T.S, Rossmann, M.G.
登録日2000-08-28
公開日2000-12-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the bacteriophage phi29 DNA packaging motor.
Nature, 408, 2000
1KMA
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NMR Structure of the Domain-I of the Kazal-type Thrombin Inhibitor Dipetalin
分子名称: DIPETALIN
著者Schlott, B, Wohnert, J, Icke, C, Hartmann, M, Ramachandran, R, Guhrs, K.-H, Glusa, E, Flemming, J, Gorlach, M, Grosse, F, Ohlenschlager, O.
登録日2001-12-14
公開日2002-05-15
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies.
J.Mol.Biol., 318, 2002
1O0L
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THE STRUCTURE OF BCL-W REVEALS A ROLE FOR THE C-TERMINAL RESIDUES IN MODULATING BIOLOGICAL ACTIVITY
分子名称: Apoptosis regulator Bcl-W
著者Hinds, M.G, Lackmann, M, Skea, G.L, Harrison, P.J, Huang, D.C.S, Day, C.L.
登録日2003-02-22
公開日2003-04-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
Embo J., 22, 2003
1O17
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ANTHRANILATE PHOSPHORIBOSYL-TRANSFERASE (TRPD)
分子名称: ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE
著者Mayans, O, Ivens, A, Kirschner, K, Wilmanns, M.
登録日2002-10-29
公開日2002-11-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry
Embo J., 21, 2002
3H0C
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Crystal Structure of Human Dipeptidyl Peptidase IV (CD26) in Complex with a Reversed Amide Inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide
著者Nordhoff, S, Cerezo-Galvez, S, Deppe, H, Hill, O, Lopez-Canet, M, Rummey, C, Thiemann, M, Matassa, V.G, Edwards, P.J, Feurer, A.
登録日2009-04-09
公開日2009-06-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Discovery of b-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV
To be Published
1G1C
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I1 DOMAIN FROM TITIN
分子名称: IMMUNOGLOBULIN-LIKE DOMAIN I1 FROM TITIN
著者Mayans, O, Wuerges, J, Gautel, M, Wilmanns, M.
登録日2000-10-11
公開日2001-10-12
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin.
Structure, 9, 2001
4K9Y
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FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-urea
分子名称: 1-[4-(6-amino-9H-purin-9-yl)phenyl]-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, Focal adhesion kinase 1
著者Musil, D, Graedler, U, Lehmann, M, Heinrich, T, Dresing, V.
登録日2013-04-21
公開日2013-09-11
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Fragment-based discovery of focal adhesion kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
3IY6
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Variable domains of the computer generated model (WAM) of Fab E fitted into the cryoEM reconstruction of the virus-Fab E complex
分子名称: fragment from neutralizing antibody E (heavy chain), fragment from neutralizing antibody E (light chain)
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
3IY1
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Variable domains of the WAM of Fab B fitted into the cryoEM reconstruction of the virus-Fab B complex
分子名称: Fab B, heavy chain, light chain
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
3IY5
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Variable domains of the mouse Fab (1AIF) fitted into the cryoEM reconstruction of the virus-Fab 16 complex
分子名称: antibody fragment IGG2A (heavy chain), antibody fragment IGG2A (light chain)
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
3IY3
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Variable domains of the computer generated model (WAM) of Fab 8 fitted into the cryoEM reconstruction of the virus-Fab 8 complex
分子名称: antibody fragment from neutralizing antibody 8 (heavy chain), antibody fragment from neutralizing antibody 8 (light chain)
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (11.1 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
3IY2
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BU of 3iy2 by Molmil
Variable domains of the computer generated model (WAM) of Fab 6 fitted into the cryoEM reconstruction of the virus-Fab 6 complex
分子名称: Antibody 6, heavy chain, light chain
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
3R9A
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Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Peroxisomal targeting signal 1 receptor, Serine--pyruvate aminotransferase
著者Fodor, K, Wilmanns, M.
登録日2011-03-25
公開日2011-05-11
最終更新日2012-05-02
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular requirements for peroxisomal targeting of alanine-glyoxylate aminotransferase as an essential determinant in primary hyperoxaluria type 1
Plos Biol., 10, 2012
3IYA
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Association of the pr peptides with dengue virus blocks membrane fusion at acidic pH
分子名称: Envelope protein, prM protein
著者Yu, I, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G, Chen, J.
登録日2009-06-01
公開日2010-04-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Association of the pr peptides with dengue virus at acidic pH blocks membrane fusion.
J.Virol., 83, 2009
3IY4
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Variable domains of the computer generated model (WAM) of Fab 15 fitted into the cryoEM reconstruction of the virus-Fab 15 complex
分子名称: fragment of neutralizing antibody 15 (heavy chain), fragment of neutralizing antibody 15 (light chain)
著者Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G.
登録日2009-04-09
公開日2009-05-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
1OOT
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Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution
分子名称: CHLORIDE ION, Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region
著者Kursula, P, Lehmann, F, Song, Y.H, Wilmanns, M.
登録日2003-03-04
公開日2004-04-06
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Crystal structure of the SH3 domain from a S. cerevisiae hypothetical 40.4 kDa protein at 1.39 A resolution
To be Published
2KD4
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Solution structure and thermodynamics of 2',5' RNA intercalation
分子名称: 5'-R(*GP*CP*CP*GP*CP*GP*GP*C)-2', PROFLAVIN
著者Horowitz, E.D, Lilavivat, S, Holladay, B.W, Germann, M.W, Hud, N.V.
登録日2009-01-02
公開日2009-04-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and thermodynamics of 2',5' RNA intercalation.
J.Am.Chem.Soc., 131, 2009
2CHC
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Structure of Rv3472(D26N), a function unknown protein from Mycobacterium tuberculosis
分子名称: PROTEIN RV3472
著者Ma, Q, Wilmanns, M.
登録日2006-03-13
公開日2007-05-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structure of Rv3472(D26N), a Function Unknown Protein from Mycobacterium Tuberculosis
To be Published
3QC7
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The structure of bacteriophage phi29 head fibers has a supercoiled triple repeating helix-turn-helix motif
分子名称: Head fiber protein
著者Xiang, Y, Rossmann, M.G.
登録日2011-01-15
公開日2011-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structure of bacteriophage {phi}29 head fibers has a supercoiled triple repeating helix-turn-helix motif.
Proc.Natl.Acad.Sci.USA, 108, 2011
2UZ5
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Solution structure of the fkbp-domain of Legionella pneumophila Mip
分子名称: MACROPHAGE INFECTIVITY POTENTIATOR
著者Ceymann, A, Horstmann, M, Ehses, P, Schweimer, K, Steinert, M, Kamphausen, T, Fischer, G, Hacker, J, Rosch, P, Faber, C.
登録日2007-04-25
公開日2007-06-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain Motions of the Mip Protein from Legionella Pneumophila
Biochemistry, 45, 2006
1RUW
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Crystal structure of the SH3 domain from S. cerevisiae Myo3
分子名称: IMIDAZOLE, Myosin-3 isoform
著者Kursula, P, Kursula, I, Lehmann, F, Song, Y.H, Wilmanns, M.
登録日2003-12-12
公開日2005-03-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the SH3 domain from S. cerevisiae Myo3
To be Published
1JNB
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CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29
分子名称: UPPER COLLAR PROTEIN
著者Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M.O, Jardine, P.J, Anderson, D.L, Rossmann, M.G.
登録日2001-07-23
公開日2001-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure determination of the head-tail connector of bacteriophage phi29.
Acta Crystallogr.,Sect.D, 57, 2001

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