2W5Q
 
 | | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | | 分子名称: | 1,2-ETHANEDIOL, MANGANESE (II) ION, PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE | | 著者 | Lu, D, Wormann, M.E, Zhang, X, Scheewind, O, Grundling, A, Freemont, P.S. | | 登録日 | 2008-12-11 | | 公開日 | 2009-02-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3H3W
 | | Fitting of the gp6 crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 dome-shaped baseplate | | 分子名称: | Baseplate structural protein Gp6 | | 著者 | Aksyuk, A.A, Leiman, P.G, Shneider, M.M, Mesyanzhinov, V.V, Rossmann, M.G. | | 登録日 | 2009-04-17 | | 公開日 | 2009-05-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | The structure of gene product 6 of bacteriophage T4, the hinge-pin of the baseplate.
Structure, 17, 2009
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7OVK
 | | Protein kinase MKK7 in complex with 5-bromo-2-hydroxyphenyl-substituted pyrazolopyrimidine | | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-(5-bromanyl-2-oxidanyl-phenyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL | | 著者 | Kleinboelting, S, Buehrmann, M, Mueller, M.P, Rauh, D. | | 登録日 | 2021-06-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries.
J.Med.Chem., 65, 2022
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7OVJ
 | | Protein kinase MKK7 in complex with difluoro-phenethyltriazole-substituted pyrazolopyrimidine | | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-[2,2-bis(fluoranyl)-2-phenyl-ethyl]-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 | | 著者 | Wiese, J.N, Buehrmann, M, Mueller, M.P, Rauh, D. | | 登録日 | 2021-06-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries.
J.Med.Chem., 65, 2022
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3H3Y
 | | Fitting of the gp6 crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 star-shaped baseplate | | 分子名称: | Baseplate structural protein Gp6 | | 著者 | Aksyuk, A.A, Leiman, P.G, Shneider, M.M, Mesyanzhinov, V.V, Rossmann, M.G. | | 登録日 | 2009-04-17 | | 公開日 | 2009-05-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (16 Å) | | 主引用文献 | The structure of gene product 6 of bacteriophage T4, the hinge-pin of the baseplate.
Structure, 17, 2009
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7OVI
 | | Protein kinase MKK7 in complex with phenethyltriazole-substituted pyrazolopyrimidine | | 分子名称: | 1-[(3~{R})-3-[4-azanyl-3-[1-(2-phenylethyl)-1,2,3-triazol-4-yl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one, Dual specificity mitogen-activated protein kinase kinase 7 | | 著者 | Kleinboelting, S, Buehrmann, M, Mueller, M.P, Rauh, D. | | 登録日 | 2021-06-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Optimization of Covalent MKK7 Inhibitors via Crude Nanomole-Scale Libraries.
J.Med.Chem., 65, 2022
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1HF0
 | | Crystal structure of the DNA-binding domain of Oct-1 bound to DNA as a dimer | | 分子名称: | DNA 5'-D(*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP* CP*AP*AP*AP*TP*GP*GP*AP*G)-3', DNA 5'-D(*CP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP* TP*CP*AP*AP*AP*TP*GP*TP*G)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1 | | 著者 | Remenyi, A, Tomilin, A, Pohl, E, Scholer, H.R, Wilmanns, M. | | 登録日 | 2000-11-27 | | 公開日 | 2001-11-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001
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1IAM
 | | STRUCTURE OF THE TWO AMINO-TERMINAL DOMAINS OF HUMAN INTERCELLULAR ADHESION MOLECULE-1, ICAM-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, INTERCELLULAR ADHESION MOLECULE-1 | | 著者 | Bella, J, Kolatkar, P.R, Marlor, C, Greve, J.M, Rossmann, M.G. | | 登録日 | 1998-02-22 | | 公開日 | 1998-04-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand.
Proc.Natl.Acad.Sci.USA, 95, 1998
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4L6W
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5DUD
 | | Crystal structure of E. coli YbgJK | | 分子名称: | YbgJ, YbgK | | 著者 | Arbing, M.A, Kaufmann, M, Shin, A, Medrano-Soto, A, Cascio, D, Eisenberg, D. | | 登録日 | 2015-09-18 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of E. coli YbgJK
To Be Published
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7Q4H
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1FPV
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3FOH
 | | Fitting of gp18M crystal structure into 3D cryo-EM reconstruction of bacteriophage T4 extended tail | | 分子名称: | Tail sheath protein Gp18 | | 著者 | Aksyuk, A.A, Leiman, P.G, Kurochkina, L.P, Shneider, M.M, Kostyuchenko, V.A, Mesyanzhinov, V.V, Rossmann, M.G. | | 登録日 | 2008-12-30 | | 公開日 | 2009-03-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (15 Å) | | 主引用文献 | The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria.
Embo J., 28, 2009
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2XGK
 | | Virus like particle of L172W mutant of Minute Virus of Mice - the immunosuppressive strain | | 分子名称: | COAT PROTEIN VP2 | | 著者 | Plevka, P, Hafenstein, S, Tattersall, P, Cotmore, S, Farr, G, D'Abramo, A, Rossmann, M.G. | | 登録日 | 2010-06-04 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structure of a Packaging-Defective Mutant of Minute Virus of Mice Indicates that the Genome is Packaged Via a Pore at a 5-Fold Axis.
J.Virol., 85, 2011
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2X80
 | | P450 BM3 F87A in complex with DMSO | | 分子名称: | BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Kuper, J, Wong, T.S, Roccatano, D, Wilmanns, M, Schwaneberg, U. | | 登録日 | 2010-03-05 | | 公開日 | 2011-03-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase.
Acta Crystallogr.,Sect.F, 68, 2012
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4KYO
 | | Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, Peroxisomal targeting signal 1 receptor, ... | | 著者 | Fodor, K, Lou, Y, Wilmanns, M. | | 登録日 | 2013-05-29 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ligand-Induced Compaction of the PEX5 Receptor-Binding Cavity Impacts Protein Import Efficiency into Peroxisomes.
Traffic, 16, 2015
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2X7Y
 | | P450 BM3 F87A in complex with DMSO | | 分子名称: | BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Kuper, J, Wong, T.S, Roccatano, D, Wilmanns, M, Schwaneberg, U. | | 登録日 | 2010-03-04 | | 公開日 | 2011-03-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Role of Active-Site Phe87 in Modulating the Organic Co-Solvent Tolerance of Cytochrome P450 Bm3 Monooxygenase.
Acta Crystallogr.,Sect.F, 68, 2012
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5EJE
 | | Crystal structure of E. coli Adenylate kinase G56C/T163C double mutant in complex with Ap5a | | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, COBALT (II) ION | | 著者 | Sauer, U.H, Kovermann, M, Grundstrom, C, Wolf-Watz, M, Sauer-Eriksson, A.E. | | 登録日 | 2015-11-01 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for ligand binding to an enzyme by a conformational selection pathway.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1IJS
 | | CPV (STRAIN D) mutant A300D, complex (VIRAL COAT/DNA), VP2, PH=7.5, T=4 DEGREES C | | 分子名称: | DNA (5'-D(*AP*C)-3'), DNA (5'-D(*CP*CP*AP*CP*CP*CP*CP*AP*A)-3'), PROTEIN (PARVOVIRUS COAT PROTEIN) | | 著者 | Llamas-Saiz, A.L, Agbandje-McKenna, M, Parker, J.S.L, Wahid, A.T.M, Parrish, C.R, Rossmann, M.G. | | 登録日 | 1996-09-12 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural analysis of a mutation in canine parvovirus which controls antigenicity and host range.
Virology, 225, 1996
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1O9W
 | | F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17A-G FIMBRIAL ADHESIN | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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4OP0
 | | Crystal structure of biotin protein ligase (RV3279C) of Mycobacterium tuberculosis, complexed with biotinyl-5'-AMP | | 分子名称: | BIOTINYL-5-AMP, BirA bifunctional protein, SULFATE ION | | 著者 | Ma, Q, Wilmanns, M, Akhter, Y. | | 登録日 | 2014-02-04 | | 公開日 | 2014-04-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis.
Protein Sci., 23, 2014
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1KGY
 | | Crystal Structure of the EphB2-ephrinB2 complex | | 分子名称: | EPHRIN TYPE-B RECEPTOR 2, EPHRIN-B2 | | 著者 | Himanen, J.P, Rajashankar, K.R, Lackmann, M, Cowan, C.A, Henkemeyer, M, Nikolov, D.B. | | 登録日 | 2001-11-28 | | 公開日 | 2002-05-28 | | 最終更新日 | 2017-02-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of an Eph receptor-ephrin complex.
Nature, 414, 2001
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1FKA
 | | STRUCTURE OF FUNCTIONALLY ACTIVATED SMALL RIBOSOMAL SUBUNIT AT 3.3 A RESOLUTION | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Schluenzen, F, Tocilj, A, Zarivach, R, Harms, J, Gluehmann, M, Janell, D, Bashan, A, Bartels, H, Agmon, I, Franceschi, F, Yonath, A. | | 登録日 | 2000-08-09 | | 公開日 | 2000-09-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution.
Cell(Cambridge,Mass.), 102, 2000
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1O9V
 | | F17-aG lectin domain from Escherichia coli in complex with a selenium carbohydrate derivative | | 分子名称: | F17-AG LECTIN DOMAIN, methyl 2-acetamido-2-deoxy-1-seleno-beta-D-glucopyranoside | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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3IYP
 | | The Interaction of Decay-accelerating Factor with Echovirus 7 | | 分子名称: | Capsid protein, Complement decay-accelerating factor, LAURIC ACID, ... | | 著者 | Plevka, P, Hafenstein, S, Zhang, Y, Harris, K.G, Cifuente, J.O, Bowman, V.D, Chipman, P.R, Lin, F, Medof, D.E, Bator, C.M, Rossmann, M.G. | | 登録日 | 2010-04-07 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Interaction of decay-accelerating factor with echovirus 7.
J.Virol., 84, 2010
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