2AB3
 
 | | Solution structures and characterization of HIV RRE IIB RNA targeting zinc finger proteins | | 分子名称: | ZINC ION, ZNF29 | | 著者 | Mishra, S.H, Shelley, C.M, Darby, M.K, Germann, M.W. | | 登録日 | 2005-07-14 | | 公開日 | 2005-08-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures and characterization of human immunodeficiency virus Rev responsive element IIB RNA targeting zinc finger proteins.
Biopolymers, 83, 2006
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2A28
 | | Atomic-resolution crystal structure of the second SH3 domain of yeast Bzz1 determined from a pseudomerohedrally twinned crystal | | 分子名称: | BZZ1 protein | | 著者 | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | | 登録日 | 2005-06-22 | | 公開日 | 2006-09-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Structural genomics of yeast SH3 domains
To be Published
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2OF6
 | | Structure of immature West Nile virus | | 分子名称: | envelope glycoprotein E | | 著者 | Zhang, Y, Kaufmann, B, Chipman, P.R, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2007-01-02 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (24 Å) | | 主引用文献 | Structure of immature west nile virus.
J.Virol., 81, 2007
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1Z7Z
 | | Cryo-em structure of human coxsackievirus A21 complexed with five domain icam-1kilifi | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Intercellular adhesion molecule-1, human coxsackievirus A21 | | 著者 | Xiao, C, Bator-Kelly, C.M, Rieder, E, Chipman, P.R, Craig, A, Kuhn, R.J, Wimmer, E, Rossmann, M.G. | | 登録日 | 2005-03-28 | | 公開日 | 2005-08-02 | | 最終更新日 | 2021-10-20 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | The crystal structure of coxsackievirus a21 and its interaction with icam-1.
Structure, 13, 2005
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2Y9M
 | | Pex4p-Pex22p structure | | 分子名称: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | | 著者 | Williams, C, van den Berg, M, Panjikar, S, Distel, B, Wilmanns, M. | | 登録日 | 2011-02-15 | | 公開日 | 2011-10-26 | | 最終更新日 | 2017-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights Into Ubiquitin-Conjugating Enzyme/ Co-Activator Interactions from the Structure of the Pex4P:Pex22P Complex.
Embo J., 31, 2011
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3LCY
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3ONM
 | | Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis | | 分子名称: | Transcriptional regulator LrhA | | 著者 | Quade, N, Diekmann, M, Haffke, M, Heroven, A.K, Dersch, P, Heinz, D.W. | | 登録日 | 2010-08-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis.
Acta Crystallogr.,Sect.D, 67, 2011
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2LB4
 | | DNA / RNA Hybrid containing a central stereo specific Sp borano phosphate linkage | | 分子名称: | DNA_(5'-D(*AP*TP*GP*GP*TP*BGR*CP*TP*C)-3')_, RNA_(5'-R(*GP*AP*GP*CP*AP*CP*CP*AP*U)-3')_ | | 著者 | Johnson, C.N, Spring, A.M, Shaw, B.R, Germann, M.W. | | 登録日 | 2011-03-22 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of the RNase H1 Activity on Stereo Regular Borano Phosphonate DNA/RNA Hybrids.
Biochemistry, 50, 2011
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5G2N
 | | X-ray structure of PI3Kinase Gamma in complex with Copanlisib | | 分子名称: | 2-azanyl-~{N}-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM, SULFATE ION | | 著者 | Schaefer, M, Scott, W.J, Hentemann, M.F, Rowley, R.B, Bull, C.O, Jenkins, S, Bullion, A.M, Johnson, J, Redman, A, Robbins, A.H, Esler, W, Fracasso, R.P, Garrison, T, Hamilton, M, Michels, M, Wood, J.E, Wilkie, D.P, Xiao, H, Levy, J, Liu, N, Stasik, E, Brands, M, Lefranc, J. | | 登録日 | 2016-04-11 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Discovery and Sar of Novel 2,3-Dihydroimidazo(1,2-C)Quinazoline Pi3K Inhibitors: Identification of Copanlisib (Bay 80-6946)
Chemmedchem, 11, 2016
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3HDA
 | | PrtC methionine mutants: M226A_DESY | | 分子名称: | CALCIUM ION, CHLORIDE ION, Secreted protease C, ... | | 著者 | Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U. | | 登録日 | 2009-05-07 | | 公開日 | 2009-06-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.131 Å) | | 主引用文献 | Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
Biol.Chem., 390, 2009
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2LDX
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6ZVA
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4K8A
 | | Fragment-based discovery of Focal Adhesion Kinase Inhibitors | | 分子名称: | 3-bromo-5-(2H-tetrazol-5-yl)pyridine, Focal adhesion kinase 1 | | 著者 | Graedler, U, Bomke, J, Musil, D, Dresing, V, Lehmann, M, Hoelzemann, G, Esdar, C, Krier, M, Heinrich, T. | | 登録日 | 2013-04-18 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Fragment-based discovery of focal adhesion kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
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3J2X
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3J2N
 | | The X-ray structure of the gp15 hexamer and the model of the gp18 protein fitted into the cryo-EM reconstruction of the contracted T4 tail | | 分子名称: | Tail connector protein Gp15, Tail sheath protein Gp18 | | 著者 | Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G. | | 登録日 | 2012-11-10 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (16 Å) | | 主引用文献 | The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
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7B9F
 | | Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | | 分子名称: | EccB5, EccC5, EccD5, ... | | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | | 登録日 | 2020-12-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Sci Adv, 7, 2021
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7B9S
 | | Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | | 分子名称: | EccB5, EccC5, EccD5, ... | | 著者 | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | | 登録日 | 2020-12-14 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Sci Adv, 7, 2021
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3J30
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3J2Y
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8CQV
 | | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_3392) | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | | 登録日 | 2023-03-07 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron
To Be Published
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1YE8
 | | Crystal Structure of THEP1 from the hyperthermophile Aquifex aeolicus | | 分子名称: | Hypothetical UPF0334 kinase-like protein AQ_1292, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Rossbach, M, Daumke, O, Klinger, C, Wittinghofer, A, Kaufmann, M. | | 登録日 | 2004-12-28 | | 公開日 | 2005-03-29 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold
BMC Struct.Biol., 5, 2005
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1ORV
 | | Crystal Structure of Porcine Dipeptidyl Peptidase IV (CD26) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | | 著者 | Engel, M, Hoffmann, T, Wagner, L, Wermann, M, Heiser, U, Kiefersauer, R, Huber, R, Bode, W, Demuth, H.U, Brandstetter, H. | | 登録日 | 2003-03-16 | | 公開日 | 2003-05-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Crystal Structure of Dipeptidyl Peptidase IV (CD26) Reveals its Functional Regulation and Enzymatic Mechanism
Proc.Natl.Acad.Sci.USA, 100, 2003
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2YK1
 | | Structure of human anti-nicotine Fab fragment in complex with nicotine | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, FAB FRAGMENT, HEAVY CHAIN, ... | | 著者 | Tars, K, Kotelovica, S, Lipowsky, G, Bauer, M, Beerli, R, Bachmann, M, Maurer, P. | | 登録日 | 2011-05-25 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Different Binding Modes of Free and Carrier-Protein-Coupled Nicotine in a Human Monoclonal Antibody.
J.Mol.Biol., 415, 2012
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3MUC
 | | MUCONATE CYCLOISOMERASE VARIANT I54V | | 分子名称: | MANGANESE (II) ION, PROTEIN (MUCONATE CYCLOISOMERASE) | | 著者 | Schell, U, Helin, S, Kajander, T, Schlomann, M, Goldman, A. | | 登録日 | 1998-10-27 | | 公開日 | 1999-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the activity of two muconate cycloisomerase variants toward substituted muconates.
Proteins, 34, 1999
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3HBU
 | | PrtC methionine mutants: M226H DESY | | 分子名称: | CALCIUM ION, CHLORIDE ION, Secreted protease C, ... | | 著者 | Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U. | | 登録日 | 2009-05-05 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site
Biol.Chem., 390, 2009
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