7KQX
 
 | | MIF Y99C homotrimeric mutant | | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | | 著者 | Manjula, R, Georgios, P, Lolis, E.J. | | 登録日 | 2020-11-18 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies.
Front Mol Biosci, 9, 2022
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6LAY
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7VWW
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8DQA
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8DQ6
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7MW7
 | | Crystal structure of P1G mutant of D-dopachrome tautomerase | | 分子名称: | D-dopachrome decarboxylase, SODIUM ION, SULFATE ION | | 著者 | Manjula, R, Murphy, E.L, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-15 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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8AP3
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6L4J
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6L44
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6L4N
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6L4I
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7D75
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7DA8
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7EUA
 | | X-ray structure of a P93A Monellin mutant | | 分子名称: | Monellin, SULFATE ION | | 著者 | Manjula, R, Bhatia, S, Jayant, B, Ramaswamy, S, Gosavi, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | X-ray structure of a P93A Monellin mutant
To Be Published
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5YTU
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5YUL
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6A9O
 | | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis | | 分子名称: | 2'-[(6-oxo-5,6-dihydrophenanthridin-3-yl)carbamoyl][1,1'-biphenyl]-2-carboxylic acid, DIMETHYL SULFOXIDE, Dihydrogen tetrasulfide, ... | | 著者 | Manjula, R, Padmanabhan, B. | | 登録日 | 2018-07-14 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis.
J.Biomol.Struct.Dyn., 37, 2019
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7MRU
 | | Crystal structure of S62A MIF2 mutant | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-dopachrome decarboxylase | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-09 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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7MSE
 | | High-resolution crystal structure of hMIF2 with tartrate at the active site | | 分子名称: | D-dopachrome decarboxylase, L(+)-TARTARIC ACID | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-11 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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7MRV
 | | F100A mutant structure of MIF2 (D-DT) | | 分子名称: | D-dopachrome decarboxylase, SULFATE ION | | 著者 | Murphy, E.L, Manjula, R, Murphy, J.W, Lolis, E. | | 登録日 | 2021-05-09 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase.
J.Biol.Chem., 297, 2021
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4YZO
 | | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Padmanabhan, B, Manjula, R, Yokoyama, S, Bessho, Y. | | 登録日 | 2015-03-25 | | 公開日 | 2016-03-30 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure Analysis of Thiolase-like protein, ST0096 from Sulfolobus Tokodaii
To Be Published
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5YTO
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