4NUF
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![BU of 4nuf by Molmil](/molmil-images/mine/4nuf) | Crystal Structure of SHP/EID1 | 分子名称: | EID1 peptide, Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, ... | 著者 | Zhi, X, Zhou, X.E, He, Y, Zechner, C, Suino-Powell, K.M, Kliewer, S.A, Melcher, K, Mangelsdorf, D.J, Xu, H.E. | 登録日 | 2013-12-03 | 公開日 | 2014-01-29 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into gene repression by the orphan nuclear receptor SHP. Proc.Natl.Acad.Sci.USA, 111, 2014
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1LUW
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![BU of 1luw by Molmil](/molmil-images/mine/1luw) | CATALYTIC AND STRUCTURAL EFFECTS OF AMINO-ACID SUBSTITUTION AT HIS 30 IN HUMAN MANGANESE SUPEROXIDE DISMUTASE: INSERTION OF VAL CGAMMA INTO THE SUBSTRATE ACCESS CHANNEL | 分子名称: | MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] | 著者 | Hearn, A.S, Stroupe, M.E, Ramilo, C.A, Luba, J.P, Cabelli, D.E, Tainer, J.A, Silverman, D.N. | 登録日 | 2002-05-23 | 公開日 | 2002-06-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel Biochemistry, 42, 2003
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1LUV
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![BU of 1luv by Molmil](/molmil-images/mine/1luv) | CATALYTIC AND STRUCTURAL EFFECTS OF AMINO-ACID SUBSTITUTION AT HIS 30 IN HUMAN MANGANESE SUPEROXIDE DISMUTASE: INSERTION OF VAL CGAMMA INTO THE SUBSTRATE ACCESS CHANNEL | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn] | 著者 | Hearn, A.S, Stroupe, M.E, Ramilo, C.A, Luba, J.P, Cabelli, D.E, Tainer, J.A, Silverman, D.N. | 登録日 | 2002-05-23 | 公開日 | 2002-06-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel Biochemistry, 42, 2003
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2F1F
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![BU of 2f1f by Molmil](/molmil-images/mine/2f1f) | Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Acetolactate synthase isozyme III small subunit, MAGNESIUM ION, ... | 著者 | Kaplun, A, Vyazmensky, M, Barak, Z, Chipman, D.M, Shaanan, B. | 登録日 | 2005-11-14 | 公開日 | 2006-01-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of the Regulatory Subunit of Acetohydroxyacid Synthase Isozyme III from Escherichia coli. J.Mol.Biol., 357, 2006
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4JLS
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![BU of 4jls by Molmil](/molmil-images/mine/4jls) | Crystal Structure of E. coli XGPRT in complex with (3R,4S)-4-(Guanin-9-yl)-3-hydroxypyrrolidin-1-N-ylacetylphosphonic acid | 分子名称: | Xanthine phosphoribosyltransferase, {2-[(3S,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxypyrrolidin-1-yl]-2-oxoethyl}phosphonic acid | 著者 | Keough, D.T, Hockova, D, Rejman, D, Spacek, P, Vrbkova, S, Krecmerova, M, Eng, W.S, Jans, H, West, N.P, Naesens, L.M.J, de Jersey, J, Guddat, L.W. | 登録日 | 2013-03-12 | 公開日 | 2014-12-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents. J.Med.Chem., 56, 2013
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4KNC
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![BU of 4knc by Molmil](/molmil-images/mine/4knc) | Structural and functional characterization of Pseudomonas aeruginosa AlgX | 分子名称: | Alginate biosynthesis protein AlgX | 著者 | Riley, L.M, Weadge, J.T, Baker, P, Robinson, H, Codee, J.D.C, Tipton, P.A, Ohman, D.E, Howell, P.L. | 登録日 | 2013-05-09 | 公開日 | 2013-06-26 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.141 Å) | 主引用文献 | Structural and Functional Characterization of Pseudomonas aeruginosa AlgX: ROLE OF AlgX IN ALGINATE ACETYLATION. J.Biol.Chem., 288, 2013
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7RS6
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![BU of 7rs6 by Molmil](/molmil-images/mine/7rs6) | Cryo-EM structure of Kip3 (AMPPNP) bound to GMPCPP-Stabilized Microtubules | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R. | 登録日 | 2021-08-11 | 公開日 | 2022-08-17 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization Biorxiv, 2024
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7RS5
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![BU of 7rs5 by Molmil](/molmil-images/mine/7rs5) | Cryo-EM structure of Kip3 (AMPPNP) bound to Taxol-Stabilized Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hernandez-Lopez, R.A, Leschziner, A.E, Arellano-Santoyo, H, Pellman, D, Stokasimov, E, Wang, R.Y.-R. | 登録日 | 2021-08-10 | 公開日 | 2022-08-17 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Multimodal tubulin binding by the yeast kinesin-8, Kip3, underlies its motility and depolymerization Biorxiv, 2021
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7S6O
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![BU of 7s6o by Molmil](/molmil-images/mine/7s6o) | The crystal structure of Lys48-linked di-ubiquitin | 分子名称: | ACETATE ION, Ubiquitin | 著者 | Osipiuk, J, Tesar, C, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A. | 登録日 | 2021-09-14 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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4KVR
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![BU of 4kvr by Molmil](/molmil-images/mine/4kvr) | Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase (mutant V41Y) | 分子名称: | Aldehyde decarbonylase, FE (III) ION, HEXANOIC ACID | 著者 | Levy, C.W, Khara, B, Menon, N, Mansell, D, Das, D, Marsh, E.N.G, Leys, D, Scrutton, N.S. | 登録日 | 2013-05-23 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase. Chembiochem, 14, 2013
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4MF3
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![BU of 4mf3 by Molmil](/molmil-images/mine/4mf3) | Crystal Structure of Human GRIK1 complexed with a 6-(tetrazolyl)aryl decahydroisoquinoline antagonist | 分子名称: | (3S,4aS,6S,8aR)-6-[3-chloro-2-(1H-tetrazol-5-yl)phenoxy]decahydroisoquinoline-3-carboxylic acid, Glutamate receptor ionotropic, kainate 1 | 著者 | Martinez-Perez, J.A, Iyengar, S, Shannon, H.E, Bleakman, D, Alt, A, Clawson, D.K, Arnold, B.M, Bell, M.G, Bleisch, T.J, Castano, A.M, Del Prado, M, Dominguez, E, Escribano, A.M, Filla, S.A, Ho, K.H, Hudziak, K.J, Jones, C.K, Katofiasc, M.A, Mateo, A, Mathes, B.M, Mattiuz, E.L, Ogden, A.M.L, Phebus, L.A, Simmons, R.M.A, Stack, D.R, Stratford, R.E, Winter, M.A, Wu, Z, Ornstein, P.L. | 登録日 | 2013-08-27 | 公開日 | 2014-05-07 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy. Bioorg.Med.Chem.Lett., 23, 2013
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6U07
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![BU of 6u07 by Molmil](/molmil-images/mine/6u07) | Computational Stabilization of T Cell Receptor Constant Domains | 分子名称: | MAGNESIUM ION, Stabilized T cell receptor constant domain (Calpha), Stabilized T cell receptor constant domain (Cbeta) | 著者 | Froning, K, Maguire, J, Sereno, A, Huang, F, Chang, S, Weichert, K, Frommelt, A.J, Dong, J, Wu, X, Austin, H, Conner, E.M, Fitchett, J.R, Heng, A.R, Balasubramaniam, D, Hilgers, M.T, Kuhlman, B, Demarest, S.J. | 登録日 | 2019-08-13 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics. Nat Commun, 11, 2020
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1F2M
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![BU of 1f2m by Molmil](/molmil-images/mine/1f2m) | |
1F2Y
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![BU of 1f2y by Molmil](/molmil-images/mine/1f2y) | |
7S3T
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![BU of 7s3t by Molmil](/molmil-images/mine/7s3t) | NzeB Diketopiperazine Dimerase Mutant: Q68I-G87A-A89G-I90V | 分子名称: | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | 著者 | Harris, N.R, Shende, V.V, Sanders, J.N, Newmister, S.A, Khatri, Y, Movassaghi, M, Houk, K.N, Sherman, D.H. | 登録日 | 2021-09-08 | 公開日 | 2022-10-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases. Angew.Chem.Int.Ed.Engl., 2023
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2RVP
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![BU of 2rvp by Molmil](/molmil-images/mine/2rvp) | Solution structure of DNA Containing Metallo-Base-Pair | 分子名称: | DNA (5'-D(*TP*AP*AP*TP*AP*TP*AP*CP*TP*TP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*TP*TP*AP*AP*CP*TP*AP*TP*AP*TP*TP*A)-3'), SILVER ION | 著者 | Dairaku, T, Furuita, K, Sato, H, Sebera, J, Nakashima, K, Kondo, J, Yamanaka, D, Kondo, Y, Okamoto, I, Ono, A, Sychrovsky, V, Kojima, C, Tanaka, Y. | 登録日 | 2016-03-22 | 公開日 | 2016-08-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure Determination of an Ag(I) -Mediated Cytosine-Cytosine Base Pair within DNA Duplex in Solution with (1) H/(15) N/(109) Ag NMR Spectroscopy. Chemistry, 22, 2016
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1RIP
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7S3J
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![BU of 7s3j by Molmil](/molmil-images/mine/7s3j) | Crystal Structure of AspB P450 in complex with brevianamide F substrates | 分子名称: | (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, AspB, GLYCEROL, ... | 著者 | Newmister, S.A, Shende, V.V, Harris, N.R, Sanders, J.N, Khatri, Y, Movassaghi, M, Houk, K.N, Sherman, D.H. | 登録日 | 2021-09-07 | 公開日 | 2022-11-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases. Angew.Chem.Int.Ed.Engl., 62, 2023
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1DPS
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![BU of 1dps by Molmil](/molmil-images/mine/1dps) | THE CRYSTAL STRUCTURE OF DPS, A FERRITIN HOMOLOG THAT BINDS AND PROTECTS DNA | 分子名称: | DPS, SODIUM ION | 著者 | Grant, R.A, Filman, D.J, Finkel, S.E, Kolter, R, Hogle, J.M. | 登録日 | 1998-02-23 | 公開日 | 1998-09-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of Dps, a ferritin homolog that binds and protects DNA. Nat.Struct.Biol., 5, 1998
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6ARK
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![BU of 6ark by Molmil](/molmil-images/mine/6ark) | Crystal Structure of compound 10 covalently bound to K-Ras G12C | 分子名称: | (3R)-N-(6-bromonaphthalen-2-yl)-3-hydroxy-1-propanoyl-L-prolinamide, GLYCEROL, GTPase KRas, ... | 著者 | Nnadi, C.I, Jenkins, M.L, Gentile, D.R, Bateman, L.A, Zaidman, D, Balius, T.E, Nomura, D.K, Burke, J.E, Shokat, K.M, London, N. | 登録日 | 2017-08-22 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange. J Chem Inf Model, 58, 2018
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6AWL
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![BU of 6awl by Molmil](/molmil-images/mine/6awl) | Crystal structure of human Coq9 | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, ... | 著者 | Bingman, C.A, Lohman, D.C, Smith, R.W, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | 登録日 | 2017-09-05 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Mol. Cell, 73, 2019
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4KVQ
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![BU of 4kvq by Molmil](/molmil-images/mine/4kvq) | Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase wild type with palmitic acid bound | 分子名称: | Aldehyde decarbonylase, FE (III) ION, PALMITIC ACID | 著者 | Levy, C.W, Khara, B, Menon, N, Mansell, D, Das, D, Marsh, E.N.G, Leys, D, Scrutton, N.S. | 登録日 | 2013-05-23 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.842 Å) | 主引用文献 | Production of propane and other short-chain alkanes by structure-based engineering of ligand specificity in aldehyde-deformylating oxygenase. Chembiochem, 14, 2013
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3WS6
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![BU of 3ws6 by Molmil](/molmil-images/mine/3ws6) | Crystal Structure of H-2D in complex with a mimotopic peptide | 分子名称: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | 著者 | Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-02-28 | 公開日 | 2014-03-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses J. Immunol., 193, 2014
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1EV1
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![BU of 1ev1 by Molmil](/molmil-images/mine/1ev1) | ECHOVIRUS 1 | 分子名称: | ECHOVIRUS 1, MYRISTIC ACID, PALMITIC ACID | 著者 | Wien, M.W, Filman, D.J, Hogle, J.M. | 登録日 | 1997-12-02 | 公開日 | 1999-01-27 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3.55 Å) | 主引用文献 | Structure determination of echovirus 1. Acta Crystallogr.,Sect.D, 54, 1998
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1FE4
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![BU of 1fe4 by Molmil](/molmil-images/mine/1fe4) | CRYSTAL STRUCTURE OF MERCURY-HAH1 | 分子名称: | COPPER TRANSPORT PROTEIN ATOX1, MERCURY (II) ION, SULFATE ION, ... | 著者 | Wernimont, A.K, Huffman, D.L, Lamb, A.L, O'Halloran, T.V, Rosenzweig, A.C. | 登録日 | 2000-07-20 | 公開日 | 2001-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for copper transfer by the metallochaperone for the Menkes/Wilson disease proteins. Nat.Struct.Biol., 7, 2000
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