7S6O

The crystal structure of Lys48-linked di-ubiquitin

Summary for 7S6O

• Entry DOI: 10.2210/pdb7s6o/pdb
• Related: 3NS8
• Descriptor: Ubiquitin, ACETATE ION, ... (4 entities in total)
• Functional Keywords: ubiquitin, di-ubiquitin, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 17414.85

Authors

Osipiuk, J.,Tesar, C.,Lanham, B.T.,Wydorski, P.,Fushman, D.,Joachimiak, L.,Joachimiak, A. (deposition date: 2021-09-14, release date: 2021-09-22, Last modification date: 2023-10-25)

• Primary citation: Wydorski, P.M.,Osipiuk, J.,Lanham, B.T.,Tesar, C.,Endres, M.,Engle, E.,Jedrzejczak, R.,Mullapudi, V.,Michalska, K.,Fidelis, K.,Fushman, D.,Joachimiak, A.,Joachimiak, L.A.; Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.; Nat Commun, 14:2366-2366, 2023; PubMed: 37185902; DOI: 10.1038/s41467-023-38031-5

Experimental method

X-RAY DIFFRACTION (1.25 Å)