5AIM
 
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5AIO
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8S9S
 | | Structure of the human ER membrane protein complex (EMC) in GDN | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Tomaleri, G.P, Nguyen, V.N, Voorhees, R.M. | | 登録日 | 2023-03-30 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.
J.Cell Biol., 222, 2023
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6WW7
 | | Structure of the human ER membrane protein complex in a lipid nanodisc | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ER Membrane Protein Complex Subunit 4, ... | | 著者 | Tomaleri, G.P, Januszyk, K, Pleiner, T, Inglis, A.J, Voorhees, R.M. | | 登録日 | 2020-05-08 | | 公開日 | 2020-05-27 | | 最終更新日 | 2020-08-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for membrane insertion by the human ER membrane protein complex.
Science, 369, 2020
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1RTS
 | | THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | | 登録日 | 1998-06-19 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
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7MVZ
 | | Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96-Nup145N complex (Nup188 residues 1-1858; Nic96 residues 240-301; Nup145N residues 640-732) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP145N, Nucleoporin NUP188 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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1I00
 | | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | | 著者 | Almog, R.A, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | | 登録日 | 2001-01-27 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
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2TSR
 | | THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX | | 著者 | Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R. | | 登録日 | 1998-06-19 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
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1HZW
 | | CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE | | 分子名称: | PHOSPHATE ION, THYMIDYLATE SYNTHASE | | 著者 | Almog, R, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P. | | 登録日 | 2001-01-26 | | 公開日 | 2001-05-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
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1VQ2
 | | CRYSTAL STRUCTURE OF T4-BACTERIOPHAGE DEOXYCYTIDYLATE DEAMINASE, MUTANT R115E | | 分子名称: | 3,4-DIHYDRO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, DEOXYCYTIDYLATE DEAMINASE, ZINC ION | | 著者 | Almog, R, Maley, F, Maley, G.F, Maccoll, R, Van Roey, P. | | 登録日 | 2004-12-15 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Three-Dimensional Structure of the R115E Mutant of T4-Bacteriophage 2'-Deoxycytidylate Deaminase
Biochemistry, 43, 2004
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7TBK
 | | Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (37 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7TBJ
 | | Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC | | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-06-29 | | 実験手法 | ELECTRON MICROSCOPY (23 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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5VL9
 | | Crystal structure of EilR in complex with eilO DNA element | | 分子名称: | DNA (5'-D(*GP*AP*AP*AP*GP*TP*TP*GP*GP*AP*CP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*TP*CP*CP*AP*AP*CP*TP*TP*TP*C)-3'), HEXANE-1,6-DIOL, ... | | 著者 | Pereira, J.H, Ruegg, T.L, Chen, J, Novichkov, P, DeGiovani, A, Tomaleri, G.P, Singer, S, Simmons, B, Thelen, M, Adams, P.D. | | 登録日 | 2017-04-25 | | 公開日 | 2018-06-27 | | 最終更新日 | 2022-03-16 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Jungle Express is a versatile repressor system for tight transcriptional control.
Nat Commun, 9, 2018
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5VLM
 | | Crystal structure of EilR in complex with crystal violet | | 分子名称: | CRYSTAL VIOLET, Regulatory protein TetR | | 著者 | Pereira, J.H, Ruegg, T.L, Chen, J, Novichkov, P, DeGiovani, A, Tomaleri, G.P, Singer, S, Simmons, B, Thelen, M, Adams, P.D. | | 登録日 | 2017-04-25 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.403 Å) | | 主引用文献 | Jungle Express is a versatile repressor system for tight transcriptional control.
Nat Commun, 9, 2018
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7MVW
 | | Crystal structure of Chaetomium thermophilum Nup188 NTD (residues 1-1134) | | 分子名称: | GLYCEROL, Nucleoporin NUP188 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MVX
 | | Crystal structure of the Chaetomium thermophilum Nup188-Nic96 complex (Nup188 residues 1-1858; Nic96 residues 240-301) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP188 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-06-22 | | 実験手法 | X-RAY DIFFRACTION (4.35 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MVT
 | | Crystal structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 185-1756; Nic96 residues 187-301) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP192 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MVV
 | | Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex (Nup192 residues 1-1756; Nic96 residues 240-301; Nup53 31-67; Nup145N 616-683) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP145N, Nucleoporin NUP192, ... | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MW1
 | | Crystal structure of the Homo sapiens NUP93-NUP53 complex (NUP93 residues 174-819; NUP53 residues 84-150) | | 分子名称: | Nuclear pore complex protein Nup93, Nucleoporin Nup35 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MVU
 | | Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 1-1756; Nic96 residues 240-301) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP192 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MVY
 | | Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96 complex (Nup188 residues 1-1858; Nic96 residues 240-301) | | 分子名称: | Nucleoporin NIC96, Nucleoporin NUP188 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7MW0
 | | Crystal structure of Homo sapiens NUP93 solenoid (residues 174-819) | | 分子名称: | 1,2-ETHANEDIOL, Nuclear pore complex protein Nup93 | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-05-15 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7TBI
 | | Composite structure of the S. cerevisiae nuclear pore complex (NPC) | | 分子名称: | Dyn2, Nic96 R1, Nic96 R2, ... | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (25 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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5VLG
 | | Crystal structure of EilR in complex with malachite green | | 分子名称: | MALACHITE GREEN, Regulatory protein TetR | | 著者 | Pereira, J.H, Ruegg, T.L, Chen, J, Novichkov, P, DeGiovani, A, Tomaleri, G.P, Singer, S, Simmons, B, Thelen, M, Adams, P.D. | | 登録日 | 2017-04-25 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.932 Å) | | 主引用文献 | Jungle Express is a versatile repressor system for tight transcriptional control.
Nat Commun, 9, 2018
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