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PDB: 131 件
2OIX
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Xanthomonas XopD C470A Mutant
分子名称: Xanthomonas outer protein D
著者Chosed, R, Tomchick, D.R, Brautigam, C.A, Machius, M, Orth, K.
登録日2007-01-11
公開日2007-05-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases.
J.Biol.Chem., 282, 2007
2VLG
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KinA PAS-A domain, homodimer
分子名称: ACETATE ION, CHLORIDE ION, SPORULATION KINASE A
著者Lee, J, Tomchick, D.R, Brautigam, C.A, Machius, M, Kort, R, Hellingwerf, K.J, Gardner, K.H.
登録日2008-01-14
公開日2008-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Changes at the Kina Pas-A Dimerization Interface Influence Histidine Kinase Function.
Biochemistry, 47, 2008
1U5Q
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Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
分子名称: CALCIUM ION, serine/threonine protein kinase TAO2
著者Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J.
登録日2004-07-28
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
STRUCTURE, 12, 2004
1U3D
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Crystal Structure of the PHR domain of Cryptochrome 1 from Arabidopsis thaliana with AMPPNP bound
分子名称: CHLORIDE ION, Cryptochrome 1 apoprotein, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ...
著者Brautigam, C.A, Smith, B.S, Ma, Z, Palnitkar, M, Tomchick, D.R, Machius, M, Deisenhofer, J.
登録日2004-07-21
公開日2004-08-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Proc.Natl.Acad.Sci.USA, 101, 2004
1U5R
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Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
著者Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J.
登録日2004-07-28
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
Structure, 12, 2004
1ZOA
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Crystal Structure Of A328V Mutant Of The Heme Domain Of P450Bm-3 With N-Palmitoylglycine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.
Biochemistry, 50, 2011
1ZO4
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Crystal Structure Of A328S Mutant Of The Heme Domain Of P450BM-3
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Haines, D.C, Bondlela, M, Mullin, D, Graham, S.E, Tomchick, D.R, Machius, M, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献A single active-site mutation of P450BM-3 dramatically enhances substrate binding and rate of product formation.
Biochemistry, 50, 2011
1ZO9
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Crystal Structure Of The Wild Type Heme Domain Of P450BM-3 with N-palmitoylmethionine
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Bifunctional P-450:NADPH-P450 reductase, GLYCEROL, ...
著者Hegda, A, Chen, B, Tomchick, D.R, Bondlela, M, Haines, D.C, Schaffer, N, Machius, M, Graham, S.E, Peterson, J.A.
登録日2005-05-12
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Interactions of substrates at the surface of P450s can greatly enhance substrate potency.
Biochemistry, 46, 2007
3F1P
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1O
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Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with an internally-bound artificial ligand
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, ...
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3F1N
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol.
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
3G6K
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Crystal Structure of Candida glabrata FMN Adenylyltransferase in complex with FAD and Inorganic Pyrophosphate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FMN adenylyltransferase, MAGNESIUM ION, ...
著者Huerta, C, Machius, M, Zhang, H.
登録日2009-02-06
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure and mechanism of a eukaryotic FMN adenylyltransferase.
J.Mol.Biol., 389, 2009
1Y64
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Bni1p Formin Homology 2 Domain complexed with ATP-actin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Otomo, T, Tomchick, D.R, Otomo, C, Panchal, S.C, Machius, M, Rosen, M.K.
登録日2004-12-03
公開日2005-01-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Nature, 433, 2005
2BNX
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Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1
分子名称: CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1
著者Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K.
登録日2005-04-05
公開日2005-06-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1
Mol.Cell, 18, 2005
2BWQ
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Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution
分子名称: REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, SULFATE ION
著者Dai, H, Tomchick, D.R, Garcia, J, Sudhof, T.C, Machius, M, Rizo, J.
登録日2005-07-15
公開日2005-10-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Crystal Structure of the Rim2 C(2)A-Domain at 1.4 A Resolution.
Biochemistry, 44, 2005
2CJS
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Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules
分子名称: 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ...
著者Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J.
登録日2006-04-06
公開日2006-06-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
2CMN
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A Proximal Arginine Residue in the Switching Mechanism of the FixL Oxygen Sensor
分子名称: PROTOPORPHYRIN IX CONTAINING FE, SENSOR PROTEIN FIXL
著者Gilles-Gonzalez, M.-A, Caceres, A.I, Silva Sousa, E.H, Tomchick, D.R, Brautigam, C.A, Gonzalez, C, Machius, M.
登録日2006-05-11
公開日2007-05-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium Japonicum Fixl Oxygen Sensor
J.Mol.Biol., 360, 2006
2CJT
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Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A
著者Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J.
登録日2006-04-06
公開日2006-06-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
2F60
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Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein
分子名称: GLYCEROL, Pyruvate dehydrogenase protein X component
著者Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T.
登録日2005-11-28
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex.
Structure, 14, 2006
2F5Z
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Crystal Structure of Human Dihydrolipoamide Dehydrogenase (E3) Complexed to the E3-Binding Domain of Human E3-Binding Protein
分子名称: Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, Pyruvate dehydrogenase protein X component, ...
著者Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T.
登録日2005-11-28
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex.
Structure, 14, 2006
2FQX
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PnrA from Treponema pallidum complexed with guanosine
分子名称: GUANOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
2FQW
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PnrA from Treponema pallidum as purified from E. coli (bound to inosine)
分子名称: INOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
2FQY
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PnrA from Treponema pallidum complexed with adenosine.
分子名称: ADENOSINE, Membrane lipoprotein tmpC
著者Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V.
登録日2006-01-18
公開日2006-02-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum
J.Biol.Chem., 281, 2006
1W15
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rat synaptotagmin 4 C2B domain in the presence of calcium
分子名称: CALCIUM ION, CHLORIDE ION, SODIUM ION, ...
著者Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J.
登録日2004-06-16
公開日2004-08-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004
1W16
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rat synaptotagmin 4 C2B domain in the absence of calcium
分子名称: CHLORIDE ION, SODIUM ION, SYNAPTOTAGMIN IV
著者Dai, H, Shin, O.-H, Machius, M, Tomchick, D.R, Sudhof, T.C, Rizo, J.
登録日2004-06-16
公開日2004-08-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Evolutionary Inactivation of Ca2+ Binding to Synaptotagmin 4
Nat.Struct.Mol.Biol., 11, 2004

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