8JM9
 
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8JMI
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8JMA
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8JME
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8JMH
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4DJI
 | | Structure of glutamate-GABA antiporter GadC | | 分子名称: | Probable glutamate/gamma-aminobutyrate antiporter | | 著者 | Ma, D, Lu, P.L, Yan, C.Y, Fan, C, Yin, P, Wang, J.W, Shi, Y.G. | | 登録日 | 2012-02-02 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.187 Å) | | 主引用文献 | Structure and mechanism of a glutamate-GABA antiporter
Nature, 483, 2012
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8X43
 | | human KCNQ2-CaM-Ebio1-S1 complex in the presence of PIP2 | | 分子名称: | Calmodulin-1, N-(4-azanyl-1,2-dihydroacenaphthylen-5-yl)-4-fluoranyl-benzamide, Potassium voltage-gated channel subfamily KQT member 2 | | 著者 | Ma, D, Guo, J. | | 登録日 | 2023-11-15 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Nat.Chem.Biol., 20, 2024
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8X83
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8X82
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8X84
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8W4U
 | | human KCNQ2-CaM in complex with PIP2 and HN37 | | 分子名称: | Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... | | 著者 | Ma, D, Li, X, Guo, J. | | 登録日 | 2023-08-25 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
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6M2W
 | | Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) | | 分子名称: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... | | 著者 | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | | 登録日 | 2020-03-01 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
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3MES
 | | Crystal structure of choline kinase from Cryptosporidium parvum Iowa II, cgd3_2030 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Choline kinase, DECAMETHONIUM ION, ... | | 著者 | Qiu, W, Wernimont, A, Hills, T, Lew, J, Artz, J.D, Xiao, T, Allali-Hassani, A, Vedadi, M, Kozieradzki, I, Cossar, D, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Hui, R, Ma, D, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-31 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of choline kinase from Cryptosporidium parvum Iowa II, cgd3_2030
TO BE PUBLISHED
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3FB3
 | | Crystal Structure of Trypanosoma Brucei Acetyltransferase, Tb11.01.2886 | | 分子名称: | N-acetyltransferase | | 著者 | Wernimont, A.K, Marino, K, Zhang, A.Z, Ma, D, Lin, Y.H, MacKenzie, F, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Qiu, W, Structural Genomics Consortium (SGC) | | 登録日 | 2008-11-18 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of Trypanosoma Brucei Acetyltransferase, Tb11.01.2886
TO BE PUBLISHED
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3I3G
 | | Crystal Structure of Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A | | 分子名称: | N-acetyltransferase | | 著者 | Qiu, W, Wernimont, A.K, Marino, K, Zhang, A.Z, Ma, D, Lin, Y.H, Mackenzie, F, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, J Ferguson, M.A, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2009-06-30 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structure Trypanosoma brucei N-acetyltransferase (Tb11.01.2886) at 1.86A
To be Published
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2M6I
 | | Putative pentameric open-channel structure of full-length transmembrane domains of human glycine receptor alpha1 subunit | | 分子名称: | Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit | | 著者 | Mowrey, D, Cui, T, Jia, Y, Ma, D, Makhov, A.M, Zhang, P, Tang, P, Xu, Y. | | 登録日 | 2013-03-29 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
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2M6B
 | | Structure of full-length transmembrane domains of human glycine receptor alpha1 monomer subunit | | 分子名称: | Full-Length Transmembrane Domains of Human Glycine Receptor alpha1 Subunit | | 著者 | Mowrey, D, Cui, T, Jia, Y, Ma, D, Makhov, A.M, Zhang, P, Tang, P, Xu, Y. | | 登録日 | 2013-03-28 | | 公開日 | 2013-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Open-Channel Structures of the Human Glycine Receptor alpha 1 Full-Length Transmembrane Domain.
Structure, 21, 2013
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4R12
 | | Crystal structure of the gamma-secretase component Nicastrin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Xie, T, Yan, C, Zhou, R, Zhao, Y, Sun, L, Yang, G, Lu, P, Ma, D, Shi, Y. | | 登録日 | 2014-08-03 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the gamma-secretase component nicastrin.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4TPV
 | | Crystal Structure of Hookworm Platelet Inhibitor | | 分子名称: | GLYCEROL, Platelet inhibitor | | 著者 | Andersen, J.F, Ma, D, Francischetti, I. | | 登録日 | 2014-06-09 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
Acta Crystallogr.,Sect.F, 71, 2015
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7CF9
 | | Structure of RyR1 (Ca2+/CHL) | | 分子名称: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | | 著者 | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | | 登録日 | 2020-06-24 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
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8WWQ
 | | geniposidic acid O-methyltransferase complexed with SAH and geniposidic acid | | 分子名称: | 1,2-ETHANEDIOL, Geniposidic acid, MAGNESIUM ION, ... | | 著者 | Luo, Z, Li, L, Ma, D, Zhou, H. | | 登録日 | 2023-10-26 | | 公開日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.958 Å) | | 主引用文献 | Structural insights into the substrate specificity of GAMT and divergence of seco-iridoid and closed-ring iridoid
To Be Published
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5A63
 | | Cryo-EM structure of the human gamma-secretase complex at 3.4 angstrom resolution. | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Bai, X, Yan, C, Yang, G, Lu, P, Ma, D, Sun, L, Zhou, R, Scheres, S.H.W, Shi, Y. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
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1A33
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1C5F
 | | CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A | | 分子名称: | CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 | | 著者 | Ellis, P.J, Carlow, C.K.S, Ma, D, Kuhn, P. | | 登録日 | 1999-11-22 | | 公開日 | 1999-12-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A.
Biochemistry, 39, 2000
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2M5P
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