7SZ9
 
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16:1-crypto Acyl Carrier Protein, AcpP | | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(2-{[(9Z)-hexadec-9-enoyl]amino}ethyl)-beta-alaninamide, ... | | Authors: | Mindrebo, J.T, Chen, A, Noel, J.P, Burkart, M.D. | | Deposit date: | 2021-11-26 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states.
Acta Crystallogr D Struct Biol, 78, 2022
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6VRT
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8OSP
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6HTE
 | | Sulfolobus solfataricus Tryptophan Synthase B2a | | Descriptor: | DI(HYDROXYETHYL)ETHER, PYRIDOXAL-5'-PHOSPHATE, Tryptophan synthase beta chain 2 | | Authors: | Fleming, J, Mayans, O, Bucher, R. | | Deposit date: | 2018-10-04 | | Release date: | 2018-11-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.961 Å) | | Cite: | Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.
J.Mol.Biol., 430, 2018
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6HUL
 | | Sulfolobus solfataricus Tryptophan Synthase AB Complex | | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, SERINE, ... | | Authors: | Fleming, J.R, Mayans, O. | | Deposit date: | 2018-10-08 | | Release date: | 2018-11-07 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.
J.Mol.Biol., 430, 2018
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8B0Q
 | | Deinococcus radiodurans UvrC C-terminal half | | Descriptor: | UvrABC system protein C | | Authors: | Timmins, J, Stelter, M. | | Deposit date: | 2022-09-08 | | Release date: | 2023-02-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER.
Nucleic Acids Res., 51, 2023
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7L4L
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C8-crypto Acyl Carrier Protein, AcpP | | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, SODIUM ION, ... | | Authors: | Mindrebo, J.T, Chen, A, Kim, W.E, Burkart, M.D, Noel, J.P. | | Deposit date: | 2020-12-19 | | Release date: | 2021-09-22 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases
Acs Catalysis, 11, 2021
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7L4E
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C16:1-crypto Acyl Carrier Protein, AcpP | | Descriptor: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, ... | | Authors: | Mindrebo, J.T, Chen, A, Kim, W.E, Burkart, M.D, Noel, J.P. | | Deposit date: | 2020-12-18 | | Release date: | 2021-10-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases
Acs Catalysis, 11, 2021
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1XHS
 | | Solution NMR Structure of Protein ytfP from Escherichia coli. Northeast Structural Genomics Consortium Target ER111. | | Descriptor: | Hypothetical UPF0131 protein ytfP | | Authors: | Aramini, J.M, Huang, Y.J, Swapna, G.V.T, Paranji, R.K, Xiao, R, Shastry, R, Acton, T.B, Cort, J.R, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2004-09-20 | | Release date: | 2005-01-04 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Escherichia coli ytfP expands the structural coverage of the UPF0131 protein domain family.
Proteins, 68, 2007
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1YH5
 | | Solution NMR Structure of Protein yggU from Escherichia coli. Northeast Structural Genomics Consortium Target ER14. | | Descriptor: | ORF, HYPOTHETICAL PROTEIN | | Authors: | Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Wu, M.J, Mills, J.L, Tejero, R.T, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2005-01-06 | | Release date: | 2005-02-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Hypothetical Protein Yggu from E. Coli. Northeast Structural Genomics Consortium Target Er14.
To be Published
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2KWB
 | | Minimal Constraint Solution NMR Structure of Translationally-controlled tumor protein (TCTP) from C.elegans, Northeast Structural Genomics Consortium Target WR73 | | Descriptor: | Translationally-controlled tumor protein homolog | | Authors: | Aramini, J.M, Rossi, P, Cort, J.R, Cooper, B, Maglaqui, M, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-04-02 | | Release date: | 2010-04-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Minimal Constraint Solution NMR Structure of Translationally-controlled tumor protein (TCTP) from C.elegans, Northeast Structural Genomics Consortium Target WR73
To be Published
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2JN8
 | | Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65. | | Descriptor: | Putative cytoplasmic protein | | Authors: | Aramini, J.M, Cort, J.R, Ho, C.K, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-12-29 | | Release date: | 2007-01-30 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Q8ZRJ2 from Salmonella typhimurium. Northeast Structural Genomics target StR65.
To be Published
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2K1G
 | | Solution NMR structure of lipoprotein spr from Escherichia coli K12. Northeast Structural Genomics target ER541-37-162 | | Descriptor: | Lipoprotein spr | | Authors: | Aramini, J.M, Rossi, P, Zhao, L, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Huang, Y.J, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-03-03 | | Release date: | 2008-03-18 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad.
Biochemistry, 47, 2008
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2JVD
 | | Solution NMR structure of the folded N-terminal fragment of UPF0291 protein ynzC from Bacillus subtilis. Northeast Structural Genomics target SR384-1-46 | | Descriptor: | UPF0291 protein ynzC | | Authors: | Aramini, J.M, Sharma, S, Huang, Y.J, Zhao, L, Owens, L.A, Stokes, K, Jiang, M, Xiao, R, Baran, M.C, Swapna, G.V.T, Acton, T.B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-09-18 | | Release date: | 2007-10-02 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis.
Proteins, 72, 2008
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2L05
 | | Solution NMR Structure of the Ras-binding domain of Serine/threonine-protein kinase B-raf from Homo sapiens, Northeast Structural Genomics Consortium Target HR4694F | | Descriptor: | Serine/threonine-protein kinase B-raf | | Authors: | Aramini, J.M, Janjua, H, Ciccosanti, C, Shastry, R, Huang, Y.J, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-30 | | Release date: | 2010-07-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of the Ras-binding domain of Serine/threonine-protein kinase B-raf from Homo sapiens, Northeast Structural Genomics Consortium Target HR4694F
To be Published
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2KIF
 | | Solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247. | | Descriptor: | O6-methylguanine-DNA methyltransferase | | Authors: | Aramini, J.M, Belote, R.L, Ciccosanti, C.T, Jiang, M, Rost, B, Nair, R, Swapna, G.V.T, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-05-03 | | Release date: | 2009-06-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein.
J.Biol.Chem., 285, 2010
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2LJW
 | | Solution NMR structure of Alr2454 protein from Nostoc sp. strain PCC 7120, Northeast Structural Genomics Consortium Target NsR264 | | Descriptor: | Alr2454 protein | | Authors: | Aramini, J.M, Lee, D, Ciccosanti, C, Janjua, H, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2011-09-29 | | Release date: | 2011-10-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267.
J.Struct.Funct.Genom., 13, 2012
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2K5D
 | | SOLUTION NMR STRUCTURE OF SAG0934 from Streptococcus agalactiae. NORTHEAST STRUCTURAL GENOMICS TARGET SaR32[1-108]. | | Descriptor: | uncharacterized protein SAG0934 | | Authors: | Aramini, J.M, Rossi, P, Zhao, L, Foote, E.L, Jiang, M, Xiao, R, Sharma, S, Swapna, G.VT, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-26 | | Release date: | 2008-08-26 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | SOLUTION NMR STRUCTURE OF SAG0934 from Streptococcus agalactiae. NORTHEAST STRUCTURAL GENOMICS TARGET SaR32[1-108].
To be Published
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1N91
 | | Solution NMR Structure of Protein yggU from Escherichia coli. Northeast Structural Genomics Consortium Target ER14. | | Descriptor: | orf, hypothetical protein | | Authors: | Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Wu, M.J, Mills, J.L, Tejero, R.T, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2002-11-21 | | Release date: | 2003-01-14 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Resonance assignments for the hypothetical protein yggU from Escherichia coli.
J.Biomol.Nmr, 27, 2003
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3QCT
 | | Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment | | Descriptor: | LT3015 antibody Fab fragment, heavy chain, light chain, ... | | Authors: | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | | Deposit date: | 2011-01-17 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1493 Å) | | Cite: | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
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3QCU
 | | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) | | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ... | | Authors: | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | | Deposit date: | 2011-01-17 | | Release date: | 2011-03-30 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.979 Å) | | Cite: | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
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2JRF
 | | Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387. | | Descriptor: | Tubulin polymerization-promoting protein family member 3 | | Authors: | Aramini, J.M, Rossi, P, Shastry, R, Nwosu, C, Cunningham, K, Xiao, R, Liu, J, Baran, M.C, Rajan, P.K, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-25 | | Release date: | 2007-07-17 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens.
To be Published
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2JQN
 | | Solution NMR structure of CC0527 from Caulobacter crescentus. Northeast Structural Genomics Target CCR55 | | Descriptor: | Hypothetical protein | | Authors: | Aramini, J.M, Rossi, P, Moseley, H.N.B, Wang, D, Nwosu, C, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2007-06-05 | | Release date: | 2007-07-03 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of CC0527 from Caulobacter crescentus
To be Published
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2V1C
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2VF8
 | | Crystal structure of UvrA2 from Deinococcus radiodurans | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, EXCINUCLEASE ABC SUBUNIT A, PHOSPHATE ION, ... | | Authors: | Timmins, J, Gordon, E, Caria, S, Leonard, G, Kuo, M.S, Monchois, V, McSweeney, S. | | Deposit date: | 2007-10-31 | | Release date: | 2008-12-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and Mutational Analyses of Deinococcus Radiodurans Uvra2 Provide Insight Into DNA Binding and Damage Recognition by Uvras.
Structure, 17, 2009
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