8FZK
 
 | |
8FHN
 | | Cryo-EM structure of human NCC (class 2) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
6FCO
 | | Structural and functional characterisation of Frataxin (FXN) like protein from Chaetomium thermophilum | | Descriptor: | MALONIC ACID, Mitochondrial frataxin-like protein | | Authors: | Jamshidiha, M, Rasheed, M, Pastore, A, Cota, E. | | Deposit date: | 2017-12-20 | | Release date: | 2019-01-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural and functional characterization of a frataxin from a thermophilic organism.
FEBS J., 286, 2019
|
|
1TRA
 | | RESTRAINED REFINEMENT OF THE MONOCLINIC FORM OF YEAST PHENYLALANINE TRANSFER RNA. TEMPERATURE FACTORS AND DYNAMICS, COORDINATED WATERS, AND BASE-PAIR PROPELLER TWIST ANGLES | | Descriptor: | MAGNESIUM ION, TRNAPHE | | Authors: | Westhof, E, Sundaralingam, M. | | Deposit date: | 1986-05-16 | | Release date: | 1986-07-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Restrained refinement of the monoclinic form of yeast phenylalanine transfer RNA. Temperature factors and dynamics, coordinated waters, and base-pair propeller twist angles.
Biochemistry, 25, 1986
|
|
8FH3
 | | Human IFT-A complex structures provide molecular insights into ciliary transport | | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Tubby-related protein 3, ... | | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | | Deposit date: | 2022-12-13 | | Release date: | 2023-02-22 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport.
Cell Res., 33, 2023
|
|
5Y2X
 | | Crystal structure of apo-HaloTag (M175C) | | Descriptor: | CHLORIDE ION, Haloalkane dehalogenase | | Authors: | Lee, H, Kang, M, Rhee, H, Lee, C. | | Deposit date: | 2017-07-27 | | Release date: | 2017-09-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Structure-guided synthesis of a protein-based fluorescent sensor for alkyl halides
Chem. Commun. (Camb.), 53, 2017
|
|
8FGW
 | | Human IFT-A complex structures provide molecular insights into ciliary transport | | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | | Deposit date: | 2022-12-12 | | Release date: | 2023-02-22 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport.
Cell Res., 33, 2023
|
|
8FHO
 | | Cryo-EM structure of human NCC (class 1) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, SODIUM ION, ... | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
8FHR
 | | Cryo-EM structure of human NCC (class 3-3) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
8FHP
 | | Cryo-EM structure of human NCC (class 3-1) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
1JOY
 | | SOLUTION STRUCTURE OF THE HOMODIMERIC DOMAIN OF ENVZ FROM ESCHERICHIA COLI BY MULTI-DIMENSIONAL NMR. | | Descriptor: | PROTEIN (ENVZ_ECOLI) | | Authors: | Tomomori, C, Tanaka, T, Dutta, R, Park, H, Saha, S.K, Zhu, Y, Ishima, R, Liu, D, Tong, K.I, Kurokawa, H, Qian, H, Inouye, M, Ikura, M. | | Deposit date: | 1998-12-28 | | Release date: | 2000-01-12 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ.
Nat.Struct.Biol., 6, 1999
|
|
8FK3
 | |
1U10
 | | MEPA, active form with ZN in P1 | | Descriptor: | Penicillin-insensitive murein endopeptidase, SULFATE ION, ZINC ION | | Authors: | Marcyjaniak, M, Odintsov, S.G, Sabala, I, Bochtler, M. | | Deposit date: | 2004-07-14 | | Release date: | 2004-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Peptidoglycan amidase MepA is a LAS metallopeptidase
J.Biol.Chem., 279, 2004
|
|
8F8E
 | | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound | | Descriptor: | (3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide, CITRIC ACID, DDB1- and CUL4-associated factor 1 | | Authors: | Kimani, S, Li, A, Dong, A, Li, Y, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | | Deposit date: | 2022-11-21 | | Release date: | 2023-03-01 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound
To be published
|
|
1X52
 | | Solution structures of the C-terminal domain of the human Pelota homolog (CGI-17) | | Descriptor: | Pelota homolog | | Authors: | Nameki, N, Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-15 | | Release date: | 2005-11-15 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structures of the C-terminal domain of the human Pelota homolog (CGI-17)
To be Published
|
|
8FHT
 | | Cryo-EM structure of human NCC | | Descriptor: | CHLORIDE ION, SODIUM ION, Solute carrier family 12 member 3 | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-15 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
1BHY
 | | LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF P64K FROM MASC DATA | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, P64K | | Authors: | Ramin, M, Shepard, W, Fourme, R, Kahn, R. | | Deposit date: | 1998-06-10 | | Release date: | 1998-11-04 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (4.18 Å) | | Cite: | Multiwavelength anomalous solvent contrast (MASC): derivation of envelope structure-factor amplitudes and comparison with model values.
Acta Crystallogr.,Sect.D, 55, 1999
|
|
8FHQ
 | | Cryo-EM structure of human NCC (class 3-2) | | Descriptor: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | | Authors: | Zhang, J, Fan, M, Feng, L. | | Deposit date: | 2022-12-14 | | Release date: | 2023-02-15 | | Last modified: | 2023-03-08 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter.
Nature, 614, 2023
|
|
6EXI
 | |
7ENQ
 | | Crystal structure of human NAMPT in complex with compound NAT | | Descriptor: | 2-(2-~{tert}-butylphenoxy)-~{N}-(4-hydroxyphenyl)ethanamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | | Authors: | Wang, G, Wu, C, Liu, M, Yao, H, Li, C, Wang, L, Tang, Y. | | Deposit date: | 2021-04-19 | | Release date: | 2022-05-04 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.204966 Å) | | Cite: | Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity.
Cell Res., 32, 2022
|
|
1X42
 | | Crystal structure of a haloacid dehalogenase family protein (PH0459) from Pyrococcus horikoshii OT3 | | Descriptor: | hypothetical protein PH0459 | | Authors: | Arai, R, Kukimoto-Niino, M, Sugahara, M, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-12 | | Release date: | 2005-11-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3
Protein Sci., 15, 2006
|
|
5YJE
 | | Crystal structure of HIRA(644-1017) | | Descriptor: | Protein HIRA, SULFATE ION | | Authors: | Sato, Y, Senda, M, Senda, T. | | Deposit date: | 2017-10-10 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
Nat Commun, 9, 2018
|
|
8FFD
 | | Crystal structure of manganeese bound Dps protein (PA0962) from Pseudomonas aeruginosa (cubic form) | | Descriptor: | L(+)-TARTARIC ACID, MANGANESE (II) ION, Probable dna-binding stress protein | | Authors: | Lovell, S, Seibold, S, Battaile, K.P, Rivera, M. | | Deposit date: | 2022-12-08 | | Release date: | 2023-03-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Int J Mol Sci, 24, 2023
|
|
8FF9
 | | Crystal structure of Apo Dps protein (PA0962) from Pseudomonas aeruginosa (orthorhombic form) | | Descriptor: | CHLORIDE ION, Probable dna-binding stress protein, SODIUM ION, ... | | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Rivera, M. | | Deposit date: | 2022-12-08 | | Release date: | 2023-03-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Pseudomonas aeruginosa Dps (PA0962) Functions in H 2 O 2 Mediated Oxidative Stress Defense and Exhibits In Vitro DNA Cleaving Activity.
Int J Mol Sci, 24, 2023
|
|
5ARB
 | | Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase | | Descriptor: | 5-methyl-2-(5-methylpyridin-2-yl)pyridine, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Sharma, M, Diaz-Rodriguez, A, Offen, W.A, Palm-Espling, M.E, Pordea, A, Wormald, M.R, Mcdonough, M, Davies, G.J, Davis, B.G. | | Deposit date: | 2015-09-24 | | Release date: | 2016-09-14 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Cooperative Bio-Metallic Selectivity in a Tailored Protease Enables Creation of a C-C Cross-Coupling Heckase
To be Published
|
|
