5BYZ
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![BU of 5byz by Molmil](/molmil-images/mine/5byz) | ERK5 in complex with small molecule | Descriptor: | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL, Mitogen-activated protein kinase 7 | Authors: | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | Deposit date: | 2015-06-11 | Release date: | 2016-05-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site. Acta Crystallogr D Struct Biol, 72, 2016
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5C0U
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![BU of 5c0u by Molmil](/molmil-images/mine/5c0u) | Crystal structure of the copper-bound form of MerB mutant D99S | Descriptor: | Alkylmercury lyase, BROMIDE ION, COPPER (II) ION | Authors: | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | Deposit date: | 2015-06-12 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry, 55, 2016
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1K1B
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![BU of 1k1b by Molmil](/molmil-images/mine/1k1b) | Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family | Descriptor: | B-cell lymphoma 3-encoded protein | Authors: | Michel, F, Soler-Lopez, M, Petosa, C, Cramer, P, Siebenlist, U, Mueller, C.W. | Deposit date: | 2001-09-24 | Release date: | 2001-11-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the ankyrin repeat domain of Bcl-3: a unique member of the IkappaB protein family. EMBO J., 20, 2001
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6JAO
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![BU of 6jao by Molmil](/molmil-images/mine/6jao) | Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in complex with palatinose | Descriptor: | 1,2-ETHANEDIOL, ABC transporter, periplasmic substrate-binding protein, ... | Authors: | Kanaujia, S.P, Chandravanshi, M, Gogoi, P. | Deposit date: | 2019-01-24 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter. Febs J., 287, 2020
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4LHQ
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![BU of 4lhq by Molmil](/molmil-images/mine/4lhq) | Ricin A chain bound to camelid nanobody (VHH8) | Descriptor: | Camelid nanobody, Ricin | Authors: | Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N. | Deposit date: | 2013-07-01 | Release date: | 2014-06-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies. J.Mol.Biol., 426, 2014
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1K1W
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![BU of 1k1w by Molmil](/molmil-images/mine/1k1w) | Crystal structure of 4-alpha-glucanotransferase from thermococcus litoralis | Descriptor: | 4-ALPHA-GLUCANOTRANSFERASE, CALCIUM ION, SULFATE ION, ... | Authors: | Imamura, H, Fushinobu, S, Kumasaka, T, Yamamoto, M, Jeon, B.S, Wakagi, T, Matsuzawa, H. | Deposit date: | 2001-09-26 | Release date: | 2003-06-17 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor J.BIOL.CHEM., 278, 2003
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3NXZ
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![BU of 3nxz by Molmil](/molmil-images/mine/3nxz) | Crystal Structure of UreE from Helicobacter pylori (Cu2+ bound form) | Descriptor: | COPPER (II) ION, Urease accessory protein ureE | Authors: | Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2010-07-14 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites Biochemistry, 49, 2010
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7Z1X
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![BU of 7z1x by Molmil](/molmil-images/mine/7z1x) | |
6EWI
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![BU of 6ewi by Molmil](/molmil-images/mine/6ewi) | |
1JJH
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![BU of 1jjh by Molmil](/molmil-images/mine/1jjh) | |
4LJB
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![BU of 4ljb by Molmil](/molmil-images/mine/4ljb) | Structure of a photobleached state of IrisFP under high intensity laser-light | Descriptor: | Green to red photoconvertible GPF-like protein EosFP, SULFATE ION, SULFITE ION | Authors: | Duan, C, Adam, V, Byrdin, M, Ridard, J, Kieffer-Jacquinod, S, Morlot, C, Arcizet, D, Demachy, I, Bourgeois, D. | Deposit date: | 2013-07-04 | Release date: | 2013-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9019 Å) | Cite: | Structural evidence for a two-regime photobleaching mechanism in a reversibly switchable fluorescent protein. J.Am.Chem.Soc., 135, 2013
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7YLB
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![BU of 7ylb by Molmil](/molmil-images/mine/7ylb) | |
5C5Y
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![BU of 5c5y by Molmil](/molmil-images/mine/5c5y) | |
6EWP
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![BU of 6ewp by Molmil](/molmil-images/mine/6ewp) | Mus musculus CEP120 third C2 domain (C2C) | Descriptor: | Centrosomal protein of 120 kDa, HEXAETHYLENE GLYCOL | Authors: | van Breugel, M, al-Jassar, C. | Deposit date: | 2017-11-06 | Release date: | 2018-05-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis. Cell Rep, 23, 2018
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4LIX
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3NSL
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![BU of 3nsl by Molmil](/molmil-images/mine/3nsl) | |
1JSE
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![BU of 1jse by Molmil](/molmil-images/mine/1jse) | |
6EZC
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![BU of 6ezc by Molmil](/molmil-images/mine/6ezc) | Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | Authors: | Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D. | Deposit date: | 2017-11-14 | Release date: | 2018-09-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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5C4J
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![BU of 5c4j by Molmil](/molmil-images/mine/5c4j) | Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Barnes, C.O, Calero, M, Malik, I, Spahr, H, Zhang, Q, Pullara, F, Kaplan, C.D, Calero, G. | Deposit date: | 2015-06-18 | Release date: | 2015-08-26 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble. Mol.Cell, 59, 2015
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2BZL
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![BU of 2bzl by Molmil](/molmil-images/mine/2bzl) | CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE N14 AT 1. 65 A RESOLUTION | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE, ... | Authors: | Debreczeni, J.E, Barr, A, Eswaran, J, Das, S, Burgess, N, Longman, E, Fedorov, O, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Knapp, S. | Deposit date: | 2005-08-18 | Release date: | 2005-09-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of Human Protein Tyrosine Phosphatase 14 (Ptpn14) at 1.65-A Resolution. Proteins, 63, 2006
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6JG1
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![BU of 6jg1 by Molmil](/molmil-images/mine/6jg1) | Crystal structure of barley exohydrolaseI wildtype in complex with 4I,4III,4V-S-trithiocellohexaose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Barley exohydrolase I, GLYCEROL, ... | Authors: | Luang, S, Streltsov, V.A, Hrmova, M. | Deposit date: | 2019-02-13 | Release date: | 2020-08-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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6JGB
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![BU of 6jgb by Molmil](/molmil-images/mine/6jgb) | Crystal structure of barley exohydrolaseI W286F mutant in complex with methyl 6-thio-beta-gentiobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ... | Authors: | Luang, S, Streltsov, V.A, Hrmova, M. | Deposit date: | 2019-02-13 | Release date: | 2020-08-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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6JGG
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![BU of 6jgg by Molmil](/molmil-images/mine/6jgg) | Crystal structure of barley exohydrolaseI W434F mutant in complex with methyl 2-thio-beta-sophoroside. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, ... | Authors: | Luang, S, Streltsov, V.A, Hrmova, M. | Deposit date: | 2019-02-14 | Release date: | 2020-08-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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6F0U
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![BU of 6f0u by Molmil](/molmil-images/mine/6f0u) | GLIC mutant E35A | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2017-11-20 | Release date: | 2018-01-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel. PLoS Biol., 15, 2017
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6JGQ
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![BU of 6jgq by Molmil](/molmil-images/mine/6jgq) | Crystal structure of barley exohydrolaseI W434Y mutant in complex with methyl 2-thio-beta-sophoroside. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, GLYCEROL, ... | Authors: | Luang, S, Streltsov, V.A, Hrmova, M. | Deposit date: | 2019-02-14 | Release date: | 2020-08-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
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