4NP9
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![BU of 4np9 by Molmil](/molmil-images/mine/4np9) | Structure of Rabphilin C2A domain bound to IP3 | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION | Authors: | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | Deposit date: | 2013-11-21 | Release date: | 2013-12-25 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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1QKI
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![BU of 1qki by Molmil](/molmil-images/mine/1qki) | X-RAY STRUCTURE OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (VARIANT CANTON R459L) COMPLEXED WITH STRUCTURAL NADP+ | Descriptor: | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL, GLYCOLIC ACID, ... | Authors: | Au, S.W.N, Gover, S, Lam, V.M.S, Adams, M.J. | Deposit date: | 1999-07-20 | Release date: | 2000-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human Glucose-6-Phosphate Dehydrogenase: The Crystal Structure Reveals a Structural Nadp+ Molecule and Provides Insights Into Enzyme Deficiency Structure, 8, 2000
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1MKS
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4NLI
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![BU of 4nli by Molmil](/molmil-images/mine/4nli) | Crystal structure of sheep beta-lactoglobulin (space group P3121) | Descriptor: | Beta-lactoglobulin-1/B, SULFATE ION | Authors: | Loch, J.I, Molenda, M, Kopec, M, Swiatek, S, Lewinski, K. | Deposit date: | 2013-11-14 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of two crystal forms of sheep beta-lactoglobulin with EF-loop in closed conformation Biopolymers, 101, 2014
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2NNR
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![BU of 2nnr by Molmil](/molmil-images/mine/2nnr) | Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi | Descriptor: | CHLORIDE ION, Chagasin, GLYCEROL, ... | Authors: | Redzynia, I, Bujacz, G, Ljunggren, A, Jaskolski, M, Abrahamson, M. | Deposit date: | 2006-10-24 | Release date: | 2007-07-24 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371, 2007
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1VFH
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![BU of 1vfh by Molmil](/molmil-images/mine/1vfh) | Crystal structure of alanine racemase from D-cycloserine producing Streptomyces lavendulae | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, alanine racemase | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | Deposit date: | 2004-04-13 | Release date: | 2004-09-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product. J.Biol.Chem., 279, 2004
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1VFS
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![BU of 1vfs by Molmil](/molmil-images/mine/1vfs) | Crystal structure of D-cycloserine-bound form of alanine racemase from D-cycloserine-producing Streptomyces lavendulae | Descriptor: | CHLORIDE ION, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, alanine racemase | Authors: | Noda, M, Matoba, Y, Kumagai, T, Sugiyama, M. | Deposit date: | 2004-04-19 | Release date: | 2004-09-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product. J.Biol.Chem., 279, 2004
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2B0R
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![BU of 2b0r by Molmil](/molmil-images/mine/2b0r) | Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum | Descriptor: | UNKNOWN ATOM OR ION, possible adenyl cyclase-associated protein | Authors: | Tempel, W, Dong, A, Zhao, Y, Lew, J, Kozieradzki, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Artz, J, Structural Genomics Consortium (SGC) | Deposit date: | 2005-09-14 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector J.Biol.Chem., 151, 2010
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1W29
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![BU of 1w29 by Molmil](/molmil-images/mine/1w29) | Lumazine Synthase from Mycobacterium tuberculosis bound to 3-(1,3,7- trihydro-9-D-ribityl-2,6,8-purinetrione-7-yl)butane 1-phosphate | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 4-{2,6,8-TRIOXO-9-[(2R,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL]-1,2,3,6,8,9-HEXAHYDRO-7H-PURIN-7-YL}BUTYL DIHYDROGEN PHOSPHATE, 4-{2,6,8-TRIOXO-9-[(2S,3R,4R)-2,3,4,5-TETRAHYDROXYPENTYL]-1,2,3,6,8,9-HEXAHYDRO-7H-PURIN-7-YL}BUTYL DIHYDROGEN PHOSPHATE, ... | Authors: | Morgunova, E, Meining, W, Illarionov, B, Haase, I, Fischer, M, Cushman, M, Bacher, A, Ladenstein, R. | Deposit date: | 2004-07-01 | Release date: | 2005-03-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Lumazine Synthase from Mycobacterium Tuberculosis as a Target for Rational Drug Design: Binding Mode of a New Class of Purinetrione Inhibitors(,) Biochemistry, 44, 2005
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2QGQ
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![BU of 2qgq by Molmil](/molmil-images/mine/2qgq) | Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77 | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Protein TM_1862 | Authors: | Forouhar, F, Neely, H, Hussain, M, Seetharaman, J, Fang, Y, Chen, C.X, Cunningham, K, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-29 | Release date: | 2007-07-17 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Post-translational Modification of Ribosomal Proteins: STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF RimO FROM THERMOTOGA MARITIMA, A RADICAL S-ADENOSYLMETHIONINE METHYLTHIOTRANSFERASE. J.Biol.Chem., 285, 2010
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2NBI
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![BU of 2nbi by Molmil](/molmil-images/mine/2nbi) | Structure of the PSCD-region of the cell wall protein pleuralin-1 | Descriptor: | HEP200 protein | Authors: | De Sanctis, S, Wenzler, M, Kroeger, N, Malloni, W.M, Sumper, M, Rainer, D, Zadravec, P, Brunner, E, Kremer, W, Kalbitzer, H.R. | Deposit date: | 2016-02-23 | Release date: | 2016-12-21 | Method: | SOLUTION NMR | Cite: | PSCD Domains of Pleuralin-1 from the Diatom Cylindrotheca fusiformis: NMR Structures and Interactions with Other Biosilica-Associated Proteins. Structure, 24, 2016
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2QMO
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![BU of 2qmo by Molmil](/molmil-images/mine/2qmo) | Crystal structure of dethiobiotin synthetase (bioD) from Helicobacter pylori | Descriptor: | CHLORIDE ION, Dethiobiotin synthetase | Authors: | Chruszcz, M, Xu, X, Cuff, M, Cymborowski, M, Zheng, H, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-07-16 | Release date: | 2007-07-31 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
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2MGZ
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![BU of 2mgz by Molmil](/molmil-images/mine/2mgz) | Solution structure of RBFOX family ASD-1 RRM and SUP-12 RRM in ternary complex with RNA | Descriptor: | Protein ASD-1, isoform a, Protein SUP-12, ... | Authors: | Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y. | Deposit date: | 2013-11-12 | Release date: | 2014-08-13 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing Nat.Struct.Mol.Biol., 21, 2014
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2MK0
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![BU of 2mk0 by Molmil](/molmil-images/mine/2mk0) | Structure of the PSCD4-domain of the cell wall protein pleuralin-1 from the diatom Cylindrotheca fusiformis | Descriptor: | HEP200 protein | Authors: | De Sanctis, S, Wenzler, M, Kroeger, N, Malloni, W.M, Sumper, M, Deutzmann, R, Zadravec, P, Brunner, E, Kremer, W, Kalbitzer, S.H.R. | Deposit date: | 2014-01-22 | Release date: | 2015-02-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | PSCD Domains of Pleuralin-1 from the Diatom Cylindrotheca fusiformis: NMR Structures and Interactions with Other Biosilica-Associated Proteins. Structure, 24, 2016
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2QU8
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![BU of 2qu8 by Molmil](/molmil-images/mine/2qu8) | Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Putative nucleolar GTP-binding protein 1 | Authors: | Wernimont, A.K, Lew, J, Lin, Y.H, Kozieradzki, I, Zhao, Y, Ravichandran, M, Shapiro, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Sukumar, D, Hassanali, A, Structural Genomics Consortium (SGC) | Deposit date: | 2007-08-03 | Release date: | 2007-08-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of putative nucleolar GTP-binding protein 1 PFF0625w from Plasmodium falciparum. To be Published
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7NC6
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![BU of 7nc6 by Molmil](/molmil-images/mine/7nc6) | Glutathione-S-transferase GliG in complex with cyclo[L-Phe-L-Ser]-bis-glutathione-adduct | Descriptor: | (2~{S})-2-azanyl-5-[[(2~{R})-3-[(2~{R},5~{R})-5-(hydroxymethyl)-3,6-bis(oxidanylidene)-2-(phenylmethyl)-5-sulfanyl-piperazin-2-yl]sulfanyl-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | Authors: | Groll, M, Huber, E.M. | Deposit date: | 2021-01-28 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
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7NCO
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![BU of 7nco by Molmil](/molmil-images/mine/7nco) | Glutathione-S-transferase GliG mutant K127R | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Glutathione S-transferase GliG | Authors: | Groll, M, Huber, E.M. | Deposit date: | 2021-01-29 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
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1WD6
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7NC5
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6HVY
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![BU of 6hvy by Molmil](/molmil-images/mine/6hvy) | Yeast 20S proteasome in complex with 5 (7- and 6-membered ring) | Descriptor: | (2~{S})-~{N}-[(2~{S},3~{R})-1-[(1~{S},4~{a}~{S},8~{a}~{R})-1,2,3,4,4~{a},5,6,7,8,8~{a}-decahydronaphthalen-1-yl]-4-methyl-3,4-bis(oxidanyl)pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, (2~{S})-~{N}-[(2~{S},3~{S},4~{R})-1-[(1~{S},4~{a}~{S},8~{a}~{R})-1,2,3,4,4~{a},5,6,7,8,8~{a}-decahydronaphthalen-1-yl]-4-methyl-3,5-bis(oxidanyl)pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2018-10-11 | Release date: | 2019-01-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
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7NCN
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![BU of 7ncn by Molmil](/molmil-images/mine/7ncn) | Glutathione-S-transferase GliG mutant S83A | Descriptor: | 1,2-ETHANEDIOL, Glutathione S-transferase GliG | Authors: | Groll, M, Huber, E.M. | Deposit date: | 2021-01-29 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
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1WMI
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![BU of 1wmi by Molmil](/molmil-images/mine/1wmi) | Crystal structure of archaeal RelE-RelB complex from Pyrococcus horikoshii OT3 | Descriptor: | hypothetical protein PHS013, hypothetical protein PHS014 | Authors: | Takagi, H, Kakuta, Y, Kamachi, R, Yao, M, Tanaka, I, Kimura, M. | Deposit date: | 2004-07-09 | Release date: | 2005-03-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of archaeal toxin-antitoxin RelE-RelB complex with implications for toxin activity and antitoxin effects Nat.Struct.Mol.Biol., 12, 2005
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7NC3
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6OYD
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![BU of 6oyd by Molmil](/molmil-images/mine/6oyd) | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-004 | Descriptor: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-[(2-methylpropyl)({2-[(propan-2-yl)amino]-1,3-benzoxazol-6-yl}sulfonyl)amino]butan-2-yl}carbamate, Protease | Authors: | Bulut, H, Hattori, S.I, Aoki-Ogata, H, Hayashi, H, Aoki, M, Ghosh, A.K, Mitsuya, H. | Deposit date: | 2019-05-14 | Release date: | 2020-05-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity. Sci Rep, 10, 2020
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7NCP
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![BU of 7ncp by Molmil](/molmil-images/mine/7ncp) | Glutathione-S-transferase GliG mutant K127A | Descriptor: | 1,2-ETHANEDIOL, Glutathione S-transferase GliG, SODIUM ION | Authors: | Groll, M, Huber, E.M. | Deposit date: | 2021-01-29 | Release date: | 2021-05-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin. Angew.Chem.Int.Ed.Engl., 60, 2021
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