7V73
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![BU of 7v73 by Molmil](/molmil-images/mine/7v73) | Thermostabilized human prestin in complex with chloride | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | Authors: | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-08-21 | Release date: | 2022-08-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7V7X
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![BU of 7v7x by Molmil](/molmil-images/mine/7v7x) | Structure of H194A AdaV | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, AdaV | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-22 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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3BX1
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![BU of 3bx1 by Molmil](/molmil-images/mine/3bx1) | Complex between the Barley alpha-Amylase/Subtilisin Inhibitor and the subtilisin Savinase | Descriptor: | Alpha-amylase/subtilisin inhibitor, CALCIUM ION, CHLORIDE ION, ... | Authors: | Micheelsen, P.O, Vevodova, J, Wilson, K, Skjot, M. | Deposit date: | 2008-01-11 | Release date: | 2008-07-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Mutational Analyses of the Interaction between the Barley alpha-Amylase/Subtilisin Inhibitor and the Subtilisin Savinase Reveal a Novel Mode of Inhibition J.Mol.Biol., 380, 2008
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7V75
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![BU of 7v75 by Molmil](/molmil-images/mine/7v75) | Thermostabilized human prestin in complex with salicylate | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-HYDROXYBENZOIC ACID, CHOLESTEROL, ... | Authors: | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-08-21 | Release date: | 2022-08-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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3BXV
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7V74
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![BU of 7v74 by Molmil](/molmil-images/mine/7v74) | Thermostabilized human prestin in complex with sulfate | Descriptor: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, SULFATE ION, ... | Authors: | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-08-21 | Release date: | 2022-08-31 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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5PAE
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![BU of 5pae by Molmil](/molmil-images/mine/5pae) | Crystal Structure of Factor VIIa in complex with (2S)-2-hydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide | Descriptor: | (2S)-2-hydroxy-N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]propanamide, CALCIUM ION, Coagulation factor VII heavy chain, ... | Authors: | Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. | Deposit date: | 2016-11-10 | Release date: | 2017-06-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal Structure of a Factor VIIa complex To be published
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3C7J
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![BU of 3c7j by Molmil](/molmil-images/mine/3c7j) | Crystal structure of transcriptional regulator (GntR family member) from Pseudomonas syringae pv. tomato str. DC3000 | Descriptor: | NICKEL (II) ION, Transcriptional regulator, GntR family | Authors: | Nocek, B, Sather, A, Gu, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-02-07 | Release date: | 2008-02-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of transcriptional regulator (GntR family member) from Pseudomonas syringae pv. tomato str. DC3000. To be Published
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5PAV
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![BU of 5pav by Molmil](/molmil-images/mine/5pav) | Crystal Structure of Factor VIIa in complex with N-(6-aminopyridin-3-yl)-5-hydroxy-1-phenylpyrazole-4-carboxamide | Descriptor: | CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... | Authors: | Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. | Deposit date: | 2016-11-10 | Release date: | 2017-06-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal Structure of a Factor VIIa complex To be published
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5PB6
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![BU of 5pb6 by Molmil](/molmil-images/mine/5pb6) | Crystal Structure of Factor VIIa in complex with N-[[3-[5-hydroxy-4-(1H-pyrrolo[3,2-c]pyridin-2-yl)pyrazol-1-yl]phenyl]methyl]pentanamide | Descriptor: | CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... | Authors: | Stihle, M, Mayweg, A, Roever, S, Rudolph, M.G. | Deposit date: | 2016-11-16 | Release date: | 2017-06-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure of a Factor VIIa complex To be published
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7VA6
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![BU of 7va6 by Molmil](/molmil-images/mine/7va6) | |
3BZP
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![BU of 3bzp by Molmil](/molmil-images/mine/3bzp) | Crystal structural of the mutated N262A EscU C-terminal domain | Descriptor: | EscU | Authors: | Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J. | Deposit date: | 2008-01-18 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS. Nature, 453, 2008
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7VA2
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![BU of 7va2 by Molmil](/molmil-images/mine/7va2) | |
7V97
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![BU of 7v97 by Molmil](/molmil-images/mine/7v97) | Arsenic-bound p53 DNA-binding domain mutant V272M | Descriptor: | ARSENIC, Cellular tumor antigen p53, ZINC ION | Authors: | Lu, M, Xing, Y.F, Wang, Z.Y, Ni, Y, Song, H.X. | Deposit date: | 2021-08-24 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties. Sci Transl Med, 15, 2023
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7VC3
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![BU of 7vc3 by Molmil](/molmil-images/mine/7vc3) | Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L97 and L-proline at 1.97 A resolution | Descriptor: | 4-[(3S)-3-cyclopropyl-3-(hydroxymethyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ETHANOLAMINE, ... | Authors: | Malhotra, N, Yogavel, M, Sharma, A. | Deposit date: | 2021-09-01 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.973 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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7VKA
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![BU of 7vka by Molmil](/molmil-images/mine/7vka) | Crystal Structure of GH3.6 in complex with an inhibitor | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCEROL, Indole-3-acetic acid-amido synthetase GH3.6, ... | Authors: | Wang, N, Luo, M, Bao, H, Huang, H. | Deposit date: | 2021-09-29 | Release date: | 2022-08-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation. Proc.Natl.Acad.Sci.USA, 119, 2022
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3BNW
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![BU of 3bnw by Molmil](/molmil-images/mine/3bnw) | |
3C3M
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![BU of 3c3m by Molmil](/molmil-images/mine/3c3m) | Crystal structure of the N-terminal domain of response regulator receiver protein from Methanoculleus marisnigri JR1 | Descriptor: | GLYCEROL, Response regulator receiver protein | Authors: | Patskovsky, Y, Ramagopal, U.A, Toro, R, Meyer, A.J, Dickey, M, Chang, S, Groshong, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-01-28 | Release date: | 2008-02-05 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of the N-terminal domain of response regulator receiver protein from Methanoculleus marisnigri JR1. To be Published
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3C4A
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![BU of 3c4a by Molmil](/molmil-images/mine/3c4a) | Crystal structure of vioD hydroxylase in complex with FAD from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR158 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable tryptophan hydroxylase vioD | Authors: | Forouhar, F, Neely, H, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Wang, H, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-01-29 | Release date: | 2008-02-05 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of vioD hydroxylase in complex with FAD from Chromobacterium violaceum. To be Published
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7VC2
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![BU of 7vc2 by Molmil](/molmil-images/mine/7vc2) | Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor L96 and L-proline in space group P21 | Descriptor: | 1,2-ETHANEDIOL, 4-[(3S)-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(5-methoxypyridin-3-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide, CHLORIDE ION, ... | Authors: | Yogavel, M, Malhotra, N, Sharma, A. | Deposit date: | 2021-09-01 | Release date: | 2022-09-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Targeting prolyl-tRNA synthetase via a series of ATP-mimetics to accelerate drug discovery against toxoplasmosis. Plos Pathog., 19, 2023
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3C4N
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![BU of 3c4n by Molmil](/molmil-images/mine/3c4n) | Crystal structure of DR_0571 protein from Deinococcus radiodurans in complex with ADP. Northeast Structural Genomics Consortium Target DrR125 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Uncharacterized protein DR_0571 | Authors: | Forouhar, F, Chen, Y, Seetharaman, J, Mao, L, Xiao, R, Cunningham, K, Owen, L.A, Maglaqui, M, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-01-30 | Release date: | 2008-02-26 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of DR_0571 protein from Deinococcus radiodurans in complex with ADP. To be Published
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3BRC
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![BU of 3brc by Molmil](/molmil-images/mine/3brc) | Crystal structure of a conserved protein of unknown function from Methanobacterium thermoautotrophicum | Descriptor: | Conserved protein of unknown function, PHOSPHATE ION | Authors: | Zhang, R, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-12-21 | Release date: | 2008-02-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of a conserved protein of unknown function from Methanobacterium thermoautotrophicum. To be Published
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7VRT
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![BU of 7vrt by Molmil](/molmil-images/mine/7vrt) | The unexpanded head structure of phage T4 | Descriptor: | Capsid vertex protein, Major capsid protein | Authors: | Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B. | Deposit date: | 2021-10-24 | Release date: | 2022-10-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly. Proc.Natl.Acad.Sci.USA, 119, 2022
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3BTM
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![BU of 3btm by Molmil](/molmil-images/mine/3btm) | THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI | Descriptor: | CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ... | Authors: | Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O. | Deposit date: | 1999-03-10 | Release date: | 2000-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI. J.Mol.Biol., 287, 1999
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7VS5
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![BU of 7vs5 by Molmil](/molmil-images/mine/7vs5) | The expanded head structure of phage T4 | Descriptor: | Capsid vertex protein, Major capsid protein, Small outer capsid protein | Authors: | Fang, Q, Tang, W, Fokine, A, Mahalingam, M, Shao, Q, Rossmann, M.G, Rao, V.B. | Deposit date: | 2021-10-25 | Release date: | 2022-10-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a large prolate virus capsid in unexpanded and expanded states generate insights into the icosahedral virus assembly. Proc.Natl.Acad.Sci.USA, 119, 2022
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