4ER3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4er3 by Molmil](/molmil-images/mine/4er3) | Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777 | Descriptor: | 1,2-ETHANEDIOL, 7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Histone-lysine N-methyltransferase, ... | Authors: | Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC) | Deposit date: | 2012-04-19 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
|
|
3WKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wkf by Molmil](/molmil-images/mine/3wkf) | Crystal structure of cellobiose 2-epimerase | Descriptor: | CHLORIDE ION, Cellobiose 2-epimerase, PHOSPHATE ION | Authors: | Fujiwara, T, Saburi, W, Tanaka, I, Yao, M. | Deposit date: | 2013-10-21 | Release date: | 2013-12-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.743 Å) | Cite: | Structural Insights into the Epimerization of beta-1,4-Linked Oligosaccharides Catalyzed by Cellobiose 2-Epimerase, the Sole Enzyme Epimerizing Non-anomeric Hydroxyl Groups of Unmodified Sugars J.Biol.Chem., 289, 2014
|
|
3WN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wn0 by Molmil](/molmil-images/mine/3wn0) | Crystal Structure of Streptomyces coelicolor alpha-L-arabinofuranosidase in complex with L-arabinose | Descriptor: | CALCIUM ION, CHLORIDE ION, CITRIC ACID, ... | Authors: | Fujimoto, Z, Maehara, T, Ichinose, H, Michikawa, M, Harazono, K, Kaneko, S. | Deposit date: | 2013-11-29 | Release date: | 2014-02-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and characterization of the glycoside hydrolase family 62 alpha-L-arabinofuranosidase from Streptomyces coelicolor J.Biol.Chem., 289, 2014
|
|
3WI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wi4 by Molmil](/molmil-images/mine/3wi4) | Crystal structure of wild-type PorB from Neisseria meningitidis serogroup B | Descriptor: | Major outer membrane protein P.IB | Authors: | Kattner, C, Toussi, D, Wetzler, L.M, Ruppel, N, Massari, P, Tanabe, M. | Deposit date: | 2013-09-05 | Release date: | 2014-01-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition. J.Struct.Biol., 185, 2014
|
|
2L38
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l38 by Molmil](/molmil-images/mine/2l38) | R29Q Sticholysin II mutant | Descriptor: | Sticholysin-2 | Authors: | Castrillo, I, Alegre-Cebollada, J, Martinez-del-Pozo, A, Gavilanes, J, Bruix, M. | Deposit date: | 2010-09-10 | Release date: | 2010-09-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Structure of StnIIR29Q, a defective lipid binding mutant of the sea anemone actinoporin Sticholysin II To be Published
|
|
2LHW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lhw by Molmil](/molmil-images/mine/2lhw) | Tri-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | Authors: | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | Deposit date: | 2011-08-18 | Release date: | 2012-04-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
|
|
2LI2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2li2 by Molmil](/molmil-images/mine/2li2) | Mono-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide | Authors: | Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D. | Deposit date: | 2011-08-18 | Release date: | 2012-04-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Deciphering structural elements of mucin glycoprotein recognition. Acs Chem.Biol., 7, 2012
|
|
2L4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l4x by Molmil](/molmil-images/mine/2l4x) | Solution Structure of apo-IscU(WT) | Descriptor: | Iron-sulfur cluster assembly scaffold protein | Authors: | Kim, J.H, Tonelli, M, Markley, J.L. | Deposit date: | 2010-10-19 | Release date: | 2011-12-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Three-Dimensional Structure and Determinants of Stability of the Iron-Sulfur Cluster Scaffold Protein IscU from Escherichia coli. Biochemistry, 51, 2012
|
|
2LQI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lqi by Molmil](/molmil-images/mine/2lqi) | NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation) | Descriptor: | CREB-binding protein, Forkhead box O3 | Authors: | Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M. | Deposit date: | 2012-03-06 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
2LR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lr4 by Molmil](/molmil-images/mine/2lr4) | |
2LRN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lrn by Molmil](/molmil-images/mine/2lrn) | Solution structure of a thiol:disulfide interchange protein from Bacteroides sp. | Descriptor: | Thiol:disulfide interchange protein | Authors: | Harris, R, Bandaranayake, A.D, Banu, R, Bonanno, J.B, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chaparro, R, Evans, B, Garforth, S, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Lim, S, Love, J, Matikainen, B, Patel, H, Seidel, R.D, Smith, B, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-04-10 | Release date: | 2012-04-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a thiol:disulfide interchange protein from Bacteroides sp. To be Published
|
|
1UFX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ufx by Molmil](/molmil-images/mine/1ufx) | Solution structure of the third PDZ domain of human KIAA1526 protein | Descriptor: | KIAA1526 protein | Authors: | Tochio, N, Kobayashi, N, Koshiba, S, Kigawa, T, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-06-10 | Release date: | 2003-12-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the third PDZ domain of human KIAA1526 protein To be Published
|
|
2LST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lst by Molmil](/molmil-images/mine/2lst) | Solution structure of a thioredoxin from Thermus thermophilus | Descriptor: | Thioredoxin | Authors: | Harris, R, Bandaranayake, A.D, Banu, R, Bonanno, J.B, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chaparro, R, Evans, B, Garforth, S, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Lim, S, Love, J, Matikainen, B, Patel, H, Seidel, R.D, Smith, B, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-05-04 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of a thioredoxin from Thermus thermophilus To be Published
|
|
2L8M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2l8m by Molmil](/molmil-images/mine/2l8m) | Reduced and CO-bound cytochrome P450cam (CYP101A1) | Descriptor: | CAMPHOR, CARBON MONOXIDE, CHLORIDE ION, ... | Authors: | Pochapsky, T.C, Pochapsky, S.S, Dang, M, Asciutto, E, Madura, J. | Deposit date: | 2011-01-19 | Release date: | 2011-02-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Experimentally Restrained Molecular Dynamics Simulations for Characterizing the Open States of Cytochrome P450(cam). Biochemistry, 50, 2011
|
|
3WHO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3who by Molmil](/molmil-images/mine/3who) | X-ray-Crystallographic Structure of an RNase Po1 Exhibiting Anti-tumor Activity | Descriptor: | Guanyl-specific ribonuclease Po1 | Authors: | Kobayashi, H, Katsurtani, T, Hara, Y, Motoyoshi, N, Itagaki, T, Akita, F, Higashiura, A, Yamada, Y, Suzuki, M, Inokuchi, N. | Deposit date: | 2013-08-30 | Release date: | 2014-07-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray crystallographic structure of RNase Po1 that exhibits anti-tumor activity. Biol.Pharm.Bull., 37, 2014
|
|
3WR2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wr2 by Molmil](/molmil-images/mine/3wr2) | |
2LM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lm8 by Molmil](/molmil-images/mine/2lm8) | |
2LBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lbh by Molmil](/molmil-images/mine/2lbh) | Solution Structure of the Dimeric Form of a Unliganded Bovine Neurophysin, Minimized Average Structure | Descriptor: | Neurophysin 1 | Authors: | Lee, H, Naik, M, Nguyen, T, Bracken, C, Breslow, E. | Deposit date: | 2011-03-31 | Release date: | 2012-04-04 | Method: | SOLUTION NMR | Cite: | Structural Basis of the Dimerization-Induced Increase in Neurophysin-Hormone Affinity: Interplay of Inter-Domain and Inter-Subunit Interactions To be Published
|
|
3WY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wy2 by Molmil](/molmil-images/mine/3wy2) | Crystal structure of alpha-glucosidase in complex with glucose | Descriptor: | Alpha-glucosidase, GLYCEROL, MAGNESIUM ION, ... | Authors: | Shen, X, Gai, Z, Kato, K, Yao, M. | Deposit date: | 2014-08-18 | Release date: | 2015-06-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.471 Å) | Cite: | Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism Acta Crystallogr. D Biol. Crystallogr., 71, 2015
|
|
3WZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wz1 by Molmil](/molmil-images/mine/3wz1) | Catalytic domain of beta-agarase from Microbulbifer thermotolerans JAMB-A94 | Descriptor: | Agarase, GLYCEROL, SODIUM ION | Authors: | Takagi, E, Hatada, Y, Akita, M, Ohta, Y, Yokoi, G, Miyazaki, T, Nishikawa, A, Tonozuka, T. | Deposit date: | 2014-09-12 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the catalytic domain of a GH16 beta-agarase from a deep-sea bacterium, Microbulbifer thermotolerans JAMB-A94 Biosci.Biotechnol.Biochem., 79, 2015
|
|
3X0D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x0d by Molmil](/molmil-images/mine/3x0d) | |
3X3Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x3y by Molmil](/molmil-images/mine/3x3y) | Copper amine oxidase from Arthrobacter globiformis anaerobically reduced by histamine | Descriptor: | COPPER (II) ION, GLYCEROL, POTASSIUM ION, ... | Authors: | Okajima, T, Nakanishi, S, Murakawa, T, Kataoka, M, Hayashi, H, Hamaguchi, A, Nakai, T, Kawano, Y, Yamaguchi, H, Tanizawa, K. | Deposit date: | 2015-03-10 | Release date: | 2015-08-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions. J.Biol.Chem., 290, 2015
|
|
3WY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wy9 by Molmil](/molmil-images/mine/3wy9) | Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha | Descriptor: | 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE | Authors: | Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T. | Deposit date: | 2014-08-22 | Release date: | 2014-12-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha. Nucleic Acids Res., 42, 2014
|
|
3WY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wy6 by Molmil](/molmil-images/mine/3wy6) | |
2LKJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lkj by Molmil](/molmil-images/mine/2lkj) | Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails | Descriptor: | Integrin alpha-M | Authors: | Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S. | Deposit date: | 2011-10-12 | Release date: | 2011-11-02 | Last modified: | 2011-11-16 | Method: | SOLUTION NMR | Cite: | Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails J.Biol.Chem., 2011
|
|