5H6Q
 
 | | Crystal structure of LSD1-CoREST in complex with peptide 11 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | Authors: | Kikuchi, M, Amano, Y, Sato, S, Yokoyama, S, Umezawa, N, Higuchi, T, Umehara, T. | | Deposit date: | 2016-11-14 | | Release date: | 2017-04-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.
Bioorg. Med. Chem., 25, 2017
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6Z7U
 | | Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation | | Descriptor: | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Ewert, W, Preller, M. | | Deposit date: | 2020-06-01 | | Release date: | 2020-10-21 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.58 Å) | | Cite: | Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke.
Int J Mol Sci, 21, 2020
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2ZUQ
 | | Crystal structure of DsbB-Fab complex | | Descriptor: | Disulfide bond formation protein B, Fab fragment heavy chain, Fab fragment light chain, ... | | Authors: | Inaba, K, Suzuki, M, Murakami, S. | | Deposit date: | 2008-10-28 | | Release date: | 2009-04-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Dynamic nature of disulphide bond formation catalysts revealed by crystal structures of DsbB
Embo J., 28, 2009
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2ZFY
 | | Crystal structure of human Otubain 1 | | Descriptor: | Ubiquitin thioesterase OTUB1 | | Authors: | Akutsu, M, Walker, J.R, Li, Y, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2008-01-16 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural basis and specificity of human otubain 1-mediated deubiquitination.
Biochem.J., 418, 2009
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7T80
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5H7J
 | | Crystal structure of Elongation factor 2 | | Descriptor: | Elongation factor 2, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | | Authors: | Tanzawa, T, Kato, K, Uchiumi, T, Yao, M. | | Deposit date: | 2016-11-18 | | Release date: | 2018-02-21 | | Last modified: | 2018-05-02 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
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5L1C
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5KU0
 | | expanded poliovirus in complex with VHH 17B | | Descriptor: | VHH 17B, VP1, VP2, ... | | Authors: | Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M. | | Deposit date: | 2016-07-12 | | Release date: | 2016-11-02 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
J. Virol., 91, 2017
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5H80
 | | Biotin Carboxylase domain of single-chain bacterial carboxylase | | Descriptor: | 1,2-ETHANEDIOL, Carboxylase | | Authors: | Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T. | | Deposit date: | 2015-12-23 | | Release date: | 2016-07-20 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans.
Structure, 24, 2016
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6FWO
 | | Structure of an E336Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-1,2-anhydro-mannose hydrolyzed by enzyme | | Descriptor: | (1~{S},2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, ACETATE ION, Glycosyl hydrolase family 71, ... | | Authors: | Sobala, L.F, Speciale, G, Hakki, Z, Fernandes, P.Z, Raich, L, Rojas-Cervellera, V, Bennet, A, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Lu, D, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | | Deposit date: | 2018-03-06 | | Release date: | 2019-09-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | An Epoxide Intermediate in Glycosidase Catalysis.
Acs Cent.Sci., 6, 2020
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8Q1X
 | | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | | Authors: | Roske, Y, Daumke, O, Damme, M. | | Deposit date: | 2023-08-01 | | Release date: | 2023-12-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation.
Nucleic Acids Res., 52, 2024
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5H8T
 | | Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol | | Descriptor: | RETINOL, Retinol-binding protein 1 | | Authors: | Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. | | Deposit date: | 2015-12-23 | | Release date: | 2016-03-02 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.21 Å) | | Cite: | Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.
J.Biol.Chem., 291, 2016
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8PZ3
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2ZW7
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2Z54
 | | The Influence of I47A Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir | | Descriptor: | BETA-MERCAPTOETHANOL, HIV-1 Protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE | | Authors: | Brynda, J, Klara, S, Kozisek, M, Lepsik, M, Machala, L, Konvalinka, J. | | Deposit date: | 2007-06-28 | | Release date: | 2008-07-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.
Protein Sci., 17, 2008
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2Z5M
 | | Complex of Transportin 1 with TAP NLS, crystal form 2 | | Descriptor: | Nuclear RNA export factor 1, Transportin-1 | | Authors: | Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. | | Deposit date: | 2007-07-14 | | Release date: | 2007-10-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
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8Q00
 | | TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | | Authors: | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | | Deposit date: | 2023-07-27 | | Release date: | 2023-12-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | The structural basis for deubiquitination by the fingerless USP-type effector TssM.
Life Sci Alliance, 7, 2024
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8PKD
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7SMR
 | | Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | | Deposit date: | 2021-10-26 | | Release date: | 2022-03-09 | | Last modified: | 2022-04-27 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
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8POF
 | | The crystal structure of RsSymEG1 reveals a unique form of smaller GH7 endoglucanases alongside GH7 cellobiohydrolases in protist symbionts of termites | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative glycosyl hydrolase family7, SODIUM ION | | Authors: | Haataja, T, Sandgren, M, Hansson, H, Stahlberg, J. | | Deposit date: | 2023-07-04 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The crystal structure of RsSymEG1 reveals a unique form of smaller GH7 endoglucanases alongside GH7 cellobiohydrolases in protist symbionts of termites.
Febs J., 291, 2024
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7SMM
 | | Cryo-EM structure of Torpedo acetylcholine receptor in apo form | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | | Deposit date: | 2021-10-26 | | Release date: | 2022-03-09 | | Last modified: | 2022-04-27 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
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6JY0
 | | CryoEM structure of S.typhimurium R-type straight flagellar filament made of FljB (A461V) | | Descriptor: | Flagellin | | Authors: | Yamaguchi, T, Toma, S, Terahara, N, Miyata, T, Minamino, T, Ashikara, M, Namba, K, Kato, T. | | Deposit date: | 2019-04-25 | | Release date: | 2020-02-19 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.56 Å) | | Cite: | Structural and Functional Comparison ofSalmonellaFlagellar Filaments Composed of FljB and FliC.
Biomolecules, 10, 2020
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7TDJ
 | | Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A) | | Descriptor: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ... | | Authors: | Nayak, A.R, Samso, M. | | Deposit date: | 2021-12-31 | | Release date: | 2022-03-09 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
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7SMQ
 | | Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E. | | Deposit date: | 2021-10-26 | | Release date: | 2022-03-09 | | Last modified: | 2022-04-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
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6X7F
 | | Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | | Deposit date: | 2020-05-29 | | Release date: | 2020-09-02 | | Last modified: | 2020-09-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of transcription-translation coupling.
Science, 369, 2020
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