4ZSC
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![BU of 4zsc by Molmil](/molmil-images/mine/4zsc) | Human Cyclophilin D Complexed with an Inhibitor at room temperature | 分子名称: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ethyl N-[(4-aminobenzyl)carbamoyl]glycinate | 著者 | Gelin, M, Delfosse, V, Allemand, F, Hoh, F, Sallaz-Damaz, Y, Pirocchi, M, Bourguet, W, Ferrer, J.-L, Labesse, G, Guichou, J.-F. | 登録日 | 2015-05-13 | 公開日 | 2015-08-12 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71, 2015
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8G8B
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![BU of 8g8b by Molmil](/molmil-images/mine/8g8b) | Nucleosome with human nMatn1 sequence in complex with Human Oct4 | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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8GJM
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![BU of 8gjm by Molmil](/molmil-images/mine/8gjm) | 17b10 fab in complex with full-length SARS-CoV-2 Spike G614 trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H. | 登録日 | 2023-03-16 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95, 2023
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5A7M
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![BU of 5a7m by Molmil](/molmil-images/mine/5a7m) | The structure of Hypocrea jecorina beta-xylosidase Xyl3A (Bxl1) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mikkelsen, N.E, Gudmundsson, M, Karkehabadi, S, Hansson, H, Sandgren, M, Larenas, E, Mitchinson, C, Keleman, B, Kaper, T. | 登録日 | 2015-07-08 | 公開日 | 2016-08-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Th Crystal Structure of a Fungal Glycoside Hydrolase Family 3 Beta-Xylosidase, Xyl3A from Hypocrea Jecorina To be Published
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6Z3S
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![BU of 6z3s by Molmil](/molmil-images/mine/6z3s) | Crystal structure of delta466-491 cystathionine beta-synthase from Toxoplasma gondii with O-Acetylserine | 分子名称: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, Cystathionine beta-synthase | 著者 | Fernandez-Rodriguez, C, Oyenarte, I, Conter, C, Gonzalez-Recio, I, Quintana, I, Martinez-Chantar, M, Astegno, A, Martinez-Cruz, L.A. | 登録日 | 2020-05-21 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.048 Å) | 主引用文献 | Structural insight into the unique conformation of cystathionine beta-synthase from Toxoplasma gondii . Comput Struct Biotechnol J, 19, 2021
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7ZHE
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![BU of 7zhe by Molmil](/molmil-images/mine/7zhe) | Crystal structure of CtaZ from Ruminiclostridium cellulolyticum | 分子名称: | GLYCEROL, SODIUM ION, Transcription activator effector binding | 著者 | Gude, F, Molloy, E.M, Horch, T, Dell, M, Dunbar, K.L, Krabbe, J, Groll, M, Hertweck, C. | 登録日 | 2022-04-06 | 公開日 | 2022-11-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria. Angew.Chem.Int.Ed.Engl., 61, 2022
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8GAI
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![BU of 8gai by Molmil](/molmil-images/mine/8gai) | |
6TH2
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![BU of 6th2 by Molmil](/molmil-images/mine/6th2) | Crystal structure of Mycobacterium smegmatis CoaB in complex with CTP | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, CALCIUM ION, ... | 著者 | Mendes, V, Blaszczyk, M, Bryant, O, Cory-Wright, J, Blundell, T.L. | 登録日 | 2019-11-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.844 Å) | 主引用文献 | Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site. Nat Commun, 12, 2021
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8G8E
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![BU of 8g8e by Molmil](/molmil-images/mine/8g8e) | Human Oct4 bound to nucleosome with human LIN28B sequence | 分子名称: | LIN28B DNA (32-MER), POU domain, class 5, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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6KAW
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![BU of 6kaw by Molmil](/molmil-images/mine/6kaw) | Crystal structure of CghA | 分子名称: | CghA | 著者 | Hara, K, Hashimoto, H, Yokoyama, M, Sato, M, Watanabe, K. | 登録日 | 2019-06-24 | 公開日 | 2020-06-24 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase Nat Catal, 2021
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8GJN
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![BU of 8gjn by Molmil](/molmil-images/mine/8gjn) | 17B10 fab in complex with up-RBD of SARS-CoV-2 Spike G614 trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 17B10 Fab, Light chain of 17B10 Fab, ... | 著者 | Kwon, H.J, Zhang, J, Kosikova, M, Tang, W.C, Rodriguez, U.O, Peng, H.Q, Meseda, C.A, Pedro, C.L, Schmeisser, F, Lu, J.M, Zhou, B, Davis, C.T, Wentworth, D.E, Chen, W.H, Shriver, M.C, Pasetti, M.F, Weir, J.P, Chen, B, Xie, H. | 登録日 | 2023-03-16 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Distinct in vitro and in vivo neutralization profiles of monoclonal antibodies elicited by the receptor binding domain of the ancestral SARS-CoV-2. J Med Virol, 95, 2023
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8G8G
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![BU of 8g8g by Molmil](/molmil-images/mine/8g8g) | Interaction of H3 tail in LIN28B nucleosome with Oct4 | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | 登録日 | 2023-02-17 | 公開日 | 2023-03-22 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity. Nature, 619, 2023
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1KWJ
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![BU of 1kwj by Molmil](/molmil-images/mine/1kwj) | solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans, minimized average structure | 分子名称: | HEME C, cytochrome c7 | 著者 | Assfalg, M, Bertini, I, Turano, P, Bruschi, M, Durand, M.C, Giudici-Orticoni, M.T, Dolla, A. | 登録日 | 2002-01-29 | 公開日 | 2002-02-06 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | A quick solution structure determination of the fully oxidized double mutant K9-10A cytochrome c7 from Desulfuromonas acetoxidans and mechanistic implications. J.Biomol.NMR, 22, 2002
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8G9Z
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![BU of 8g9z by Molmil](/molmil-images/mine/8g9z) | High-resolution crystal structure of the human selenomethionine-derived SepSecS-tRNASec complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, O-phosphoseryl-tRNA(Sec) selenium transferase, ... | 著者 | Puppala, A, Simonovic, M, Castillo Suchkou, J. | 登録日 | 2023-02-22 | 公開日 | 2023-04-05 | 最終更新日 | 2023-05-17 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 51, 2023
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1RS9
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![BU of 1rs9 by Molmil](/molmil-images/mine/1rs9) | Bovine endothelial NOS heme domain with D-phenylalanine-D-nitroarginine amide bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLATE ION, ... | 著者 | Flinspach, M, Li, H, Jamal, J, Yang, W, Huang, H, Silverman, R.B, Poulos, T.L. | 登録日 | 2003-12-09 | 公開日 | 2004-06-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structures of the neuronal and endothelial nitric oxide synthase heme domain with D-nitroarginine-containing dipeptide inhibitors bound. Biochemistry, 43, 2004
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6T5Z
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![BU of 6t5z by Molmil](/molmil-images/mine/6t5z) | Crystal structure of an AA10 LPMO from Photorhabdus luminescens | 分子名称: | COPPER (II) ION, Chitin-binding type-4 domain-containing protein | 著者 | Munzone, A, El Kerdi, B, Reglier, M, Royant, A, Simaan, A.J, Decroos, C. | 登録日 | 2019-10-17 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.60000312 Å) | 主引用文献 | Characterization of a bacterial copper-dependent lytic polysaccharide monooxygenase with an unusual second coordination sphere. Febs J., 287, 2020
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6T2O
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![BU of 6t2o by Molmil](/molmil-images/mine/6t2o) | Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 16 | 著者 | Crouch, L.I, Liberato, M.V, Ubranowicz, P.A, Basle, A, Lamb, C.A, Cooke, K, Doona, M, Needham, S, Brady, R.R, Berrington, J.E, Madubic, K, Chater, P, Zhang, F, Linhardt, R.J, Spence, D.I.R, Bolam, D.N. | 登録日 | 2019-10-09 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown. Nat Commun, 11, 2020
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8GLP
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![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-03-22 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8E1A
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![BU of 8e1a by Molmil](/molmil-images/mine/8e1a) | Structure-based study to overcome cross-reactivity of novel androgen receptor inhibitors | 分子名称: | 1,2-ETHANEDIOL, 4-[4-(3-fluoro-2-methoxyphenyl)-1,3-thiazol-2-yl]morpholine, Androgen receptor | 著者 | Lallous, N, Li, H, Radaeva, M, Dalal, K, Leblanc, E, Ban, F, Ciesielski, F, Chow, B, Morin, M, Singh, K, Rennie, P.S, Cherkasov, A. | 登録日 | 2022-08-10 | 公開日 | 2022-09-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors. Cells, 11, 2022
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8G5Z
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![BU of 8g5z by Molmil](/molmil-images/mine/8g5z) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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5B1F
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![BU of 5b1f by Molmil](/molmil-images/mine/5b1f) | |
6H2M
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![BU of 6h2m by Molmil](/molmil-images/mine/6h2m) | Long wavelength Mesh&Collect native SAD phasing on microcrystals | 分子名称: | CALCIUM ION, Concanavalin-A,Concanavalin-A, MANGANESE (II) ION | 著者 | Cianci, M, Nanao, M, Schneider, T.R. | 登録日 | 2018-07-13 | 公開日 | 2019-03-13 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | 主引用文献 | Long-wavelength Mesh&Collect native SAD phasing from microcrystals. Acta Crystallogr D Struct Biol, 75, 2019
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5GN5
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![BU of 5gn5 by Molmil](/molmil-images/mine/5gn5) | Crystal structure of glycerol kinase from Trypanosoma brucei gambiense complexed with cumarin derivative-17 | 分子名称: | 4-[[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-7,8-bis(oxidanyl)chromen-2-one, GLYCEROL, Glycerol kinase | 著者 | Balogun, E.O, Inaoka, D.K, Shiba, T, Tsuge, T, May, B, Sato, T, Kido, Y, Takeshi, N, Aoki, T, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Michels, P.A.M, Watanabe, Y, Moore, A.L, Harada, S, Kita, K. | 登録日 | 2016-07-19 | 公開日 | 2017-07-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase ofTrypanosoma brucei brucei. Faseb J., 33, 2019
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7LLQ
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![BU of 7llq by Molmil](/molmil-images/mine/7llq) | Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity | 分子名称: | 1-benzyl-4-methoxybenzene, 1-{4-oxo-4-[(2S)-pyrrolidin-2-yl]butanoyl}-L-proline, Leukotriene A-4 hydrolase, ... | 著者 | Lee, K.H, Lee, S.H, Shim, Y.M, Paige, M, Noble, S.M. | 登録日 | 2021-02-04 | 公開日 | 2022-06-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Substrate-dependent modulation of the leukotriene A 4 hydrolase aminopeptidase activity and effect in a murine model of acute lung inflammation. Sci Rep, 12, 2022
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5APN
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![BU of 5apn by Molmil](/molmil-images/mine/5apn) | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. | 登録日 | 2015-09-17 | 公開日 | 2015-12-16 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell, 164, 2015
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