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PDB: 52161 件

3BTK
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THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI
分子名称: CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-10
公開日2000-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
2Q8G
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Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545
分子名称: 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
著者Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
登録日2007-06-10
公開日2007-07-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
3ZQF
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Structure of Tetracycline repressor in complex with antiinducer peptide-TAP1
分子名称: ANTI-INDUCER PEPTIDE TAP1, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D
著者Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W.
登録日2011-06-09
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
2Q9H
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Crystal structure of the C73S mutant of diaminopimelate epimerase
分子名称: ACETIC ACID, Diaminopimelate epimerase, L(+)-TARTARIC ACID
著者Pillai, B, Cherney, M, Diaper, C.M, Sutherland, A, Blanchard, J.S, Vederas, J.C, James, M.N.G.
登録日2007-06-12
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
Biochem.Biophys.Res.Commun., 363, 2007
3BS8
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Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Glutamate-1-semialdehyde 2,1-aminomutase
著者Ge, H, Fan, J, Teng, M, Niu, L.
登録日2007-12-22
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Glutamate1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate
Biochem.Biophys.Res.Commun., 402, 2010
3BSU
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Hybrid-binding domain of human RNase H1 in complex with 12-mer RNA/DNA
分子名称: DNA (5'-D(*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*(5IU)P*DGP*DTP*DC)-3'), MAGNESIUM ION, RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3'), ...
著者Nowotny, M, Cerritelli, S.M, Ghirlando, R, Gaidamakov, S.A, Crouch, R.J, Yang, W.
登録日2007-12-26
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
Embo J., 27, 2008
3BTT
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THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI
分子名称: CALCIUM ION, PROTEIN (PANCREATIC TRYPSIN INHIBITOR), PROTEIN (TRYPSIN), ...
著者Helland, R, Otlewski, J, Sundheim, O, Dadlez, M, Smalas, A.O.
登録日1999-03-10
公開日2000-03-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structures of the complexes between bovine beta-trypsin and ten P1 variants of BPTI.
J.Mol.Biol., 287, 1999
1GQE
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Polypeptide Chain Release Factor 2 (RF2) from Escherichia coli
分子名称: RELEASE FACTOR 2
著者Vestergaard, B, Kjeldgaard, M.
登録日2001-11-22
公開日2002-04-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Bacterial Polypeptide Release Factor Rf2 is Structurally Distinct from Eukaryotic Erf1.
Mol.Cell, 8, 2001
2PON
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Solution structure of the Bcl-xL/Beclin-1 complex
分子名称: Apoptosis regulator Bcl-X, Beclin-1
著者Feng, W, Huang, S, Wu, H, Zhang, M.
登録日2007-04-27
公開日2007-09-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1.
J.Mol.Biol., 372, 2007
3BZL
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Crystal structural of native EscU C-terminal domain
分子名称: EscU, FORMIC ACID, SODIUM ION
著者Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J.
登録日2008-01-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
1H75
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Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like protein NrdH-redoxin from Escherichia coli.
分子名称: GLUTAREDOXIN-LIKE PROTEIN NRDH
著者Stehr, M, Schneider, G, Aslund, F, Holmgren, A, Lindqvist, Y.
登録日2001-07-03
公開日2001-08-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for the Thioredoxin-Like Activity Profile of the Glutaredoxin-Like Nrdh-Redoxin from Escherichia Coli
J.Biol.Chem., 276, 2001
3BZX
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Crystal structure of the mutated H265A EscU C-terminal domain
分子名称: EscU, SULFATE ION
著者Zarivach, R, Deng, W, Vuckovic, M, Felise, H.B, Nguyen, H.V, Miller, S.I, Finlay, B.B, Strynadka, N.C.J.
登録日2008-01-18
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaS.
Nature, 453, 2008
3ZGL
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Crystal structures of Escherichia coli IspH in complex with AMBPP a potent inhibitor of the methylerythritol phosphate pathway
分子名称: (2E)-4-amino-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, IRON/SULFUR CLUSTER
著者Borel, F, Barbier, E, Kratsutsky, S, Janthawornpong, K, Rohmer, M, Dale Poulter, C, Ferrer, J.L, Seemann, M.
登録日2012-12-18
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials.
Chembiochem, 18, 2017
6Z7A
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Variant Surface Glycoprotein VSGsur
分子名称: Variant surface glycoprotein Sur, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E, Hashemi, H.
登録日2020-05-30
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献A Parasite Coat Protein Binds Suramin to Confer Drug Resistance
Nat Microbiol, 6, 2021
3C0T
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Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18
分子名称: Mediator of RNA polymerase II transcription subunit 18, Mediator of RNA polymerase II transcription subunit 8
著者Lariviere, L, Seizl, M, van Wageningen, S, Roether, S, van de Pasch, L, Feldmann, H, Straesser, K, Hahn, S, Holstege, C.P, Cramer, P.
登録日2008-01-21
公開日2008-04-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-system correlation identifies a gene regulatory Mediator submodule
Genes Dev., 22, 2008
1QH3
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HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
分子名称: ACETATE ION, CACODYLATE ION, CHLORIDE ION, ...
著者Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B.
登録日1999-05-10
公開日1999-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
2PYE
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Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-05-16
公開日2007-09-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2PRU
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NMR Structure of Human apoS100B at 10C
分子名称: Protein S100-B
著者Malik, S, Shaw, G.S, Revington, M.
登録日2007-05-04
公開日2008-04-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins.
Proteins, 73, 2008
1HM7
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N219L PENTALENENE SYNTHASE
分子名称: PENTALENENE SYNTHASE
著者Seemann, M, Paschall, C.M, Christianson, D.W, Cane, D.E.
登録日2000-12-05
公開日2002-08-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis.
J.Am.Chem.Soc., 124, 2002
2PZP
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome
分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
3C2Q
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Crystal structure of conserved putative LOR/SDH protein from Methanococcus maripaludis S2
分子名称: IMIDAZOLE, NICKEL (II) ION, Uncharacterized conserved protein
著者Duke, N, Gu, M, Mulligan, R, Conrad, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-01-25
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of conserved putative LOR/SDH protein from Methanococcus maripaludis S2
To be Published
3ZQI
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Structure of Tetracycline repressor in complex with inducer peptide- TIP2
分子名称: 1,2-ETHANEDIOL, INDUCER PEPTIDE TIP2, MAGNESIUM ION, ...
著者Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W.
登録日2011-06-09
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
3ZCS
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Rabbit muscle glycogen phosphorylase b in complex with N-(1-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.07 A resolution
分子名称: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, INOSINIC ACID, ...
著者Chrysina, E.D, Nagy, V, Felfoldi, N, Konya, B, Telepo, K, Praly, J.P, Docsa, T, Gergely, P, Alexacou, K.M, Hayes, J.M, Konstantakaki, M, Kardakaris, R, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G, Somsak, L.
登録日2012-11-21
公開日2013-12-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Synthesis, Kinetic, Computational and Crystallographic Evaluation of N-Acyl-N-Beta-D- Glucopyranosyl)Ureas, Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase, Potential Antidiabetic Agents
To be Published
2Q16
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Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP
分子名称: CALCIUM ION, HAM1 protein homolog, INOSINE 5'-TRIPHOSPHATE, ...
著者Singer, A.U, Lam, R, Proudfoot, M, Skarina, T, Savchenko, A, Yakunin, A.F.
登録日2007-05-23
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
J.Mol.Biol., 374, 2007
1QA4
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HIV-1 NEF ANCHOR DOMAIN, NMR, 2 STRUCTURES
分子名称: Protein Nef
著者Geyer, M, Kalbitzer, H.R.
登録日1999-04-12
公開日1999-05-26
最終更新日2024-10-09
実験手法SOLUTION NMR
主引用文献Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein.
J.Mol.Biol., 289, 1999

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