1FQV
| Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | 分子名称: | SKP1, SKP2 | 著者 | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | 登録日 | 2000-09-06 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1Y55
| Crystal structure of the C122S mutant of E. Coli expressed avidin related protein 4 (AVR4)-biotin complex | 分子名称: | Avidin-related protein 4/5, BIOTIN, FORMIC ACID | 著者 | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | 登録日 | 2004-12-02 | 公開日 | 2005-05-24 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
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5BR8
| Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H. | 登録日 | 2015-05-29 | 公開日 | 2015-11-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin To Be Published
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1FS1
| INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | 分子名称: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | 著者 | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | 登録日 | 2000-09-08 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature, 408, 2000
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1Y53
| Crystal structure of bacterial expressed avidin related protein 4 (AVR4) C122S | 分子名称: | Avidin-related protein 4/5, FORMIC ACID | 著者 | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | 登録日 | 2004-12-02 | 公開日 | 2005-05-24 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
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1Y52
| structure of insect cell (Baculovirus) expressed AVR4 (C122S)-biotin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin-related protein 4/5, BIOTIN | 著者 | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | 登録日 | 2004-12-02 | 公開日 | 2005-05-24 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability. Acta Crystallogr.,Sect.D, 61, 2005
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5M92
| PCE reductive dehalogenase from S. multivorans in complex with 2,4-dibromophenol | 分子名称: | 2,4-bis(bromanyl)phenol, BENZAMIDINE, BROMIDE ION, ... | 著者 | Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. | 登録日 | 2016-10-31 | 公開日 | 2017-07-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.785 Å) | 主引用文献 | Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
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5BXY
| Crystal structure of RNA methyltransferase from Salinibacter ruber in complex with S-Adenosyl-L-homocysteine | 分子名称: | CHLORIDE ION, MAGNESIUM ION, RNA methyltransferase, ... | 著者 | Handing, K.B, LaRowe, C, Shabalin, I.G, Stead, M, Hillerich, B.S, Ahmed, M, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2015-06-09 | 公開日 | 2015-07-01 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of RNA methylase family protein from Salinibacterruber in complex with S-Adenosyl-L-homocysteine. to be published
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5MQJ
| Crystal structure of dCK mutant C3S | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | 著者 | Saez-Ayala, M, Rebuffet, E, Hammam, K, Gros, L, Lopez, S, Hajem, B, Humbert, M, Baudelet, E, Audebert, S, Betzi, S, Lugari, A, Combes, S, Pez, D, Letard, S, Mansfield, C, Moussy, A, de Sepulveda, P, Morelli, X, Dubreuil, P. | 登録日 | 2016-12-20 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology. Nat Commun, 8, 2017
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5MQW
| High-speed fixed-target serial virus crystallography | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A. | 登録日 | 2016-12-21 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-speed fixed-target serial virus crystallography. Nat. Methods, 14, 2017
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5C6K
| Bacteriophage P2 integrase catalytic domain | 分子名称: | Integrase | 著者 | Skaar, K, Claesson, M, Odegrip, R, Eriksson, J, Hogbom, M, Haggard-Ljungquist, E, Stenmark, P. | 登録日 | 2015-06-23 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the bacteriophage P2 integrase catalytic domain. Febs Lett., 589, 2015
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8R7M
| CTX-M14 in complex with boric acid and 1,2-diol boric ester | 分子名称: | BORIC ACID, Beta-lactamase, GLYCEROL, ... | 著者 | Werner, N, Prester, A, Hinrichs, W, Perbandt, M, Betzel, C. | 登録日 | 2023-11-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024
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5C9G
| Crystal Structure of a Putative enoyl-CoA hydratase/isomerase family protein from Hyphomonas neptunium | 分子名称: | D-MALATE, Enoyl-CoA hydratase/isomerase family protein, TETRAETHYLENE GLYCOL | 著者 | Szlachta, K, Cooper, D.R, Chapman, H.C, Cymbrowski, M.T, Stead, M, Hillerich, B.S, Ahmed, M, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, Hammonds, J, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2015-06-26 | 公開日 | 2015-10-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of a Putative enoyl-CoA hydratase/isomerase family protein from Hyphomonas neptunium to be published
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5M7X
| Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSepG mRNA 5' cap analog (beta-Se-ARCA D1) | 分子名称: | Eukaryotic translation initiation factor 4E, GLYCEROL, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(selanyl)phosphoryl] hydrogen phosphate | 著者 | Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M. | 登録日 | 2016-10-28 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSepG mRNA 5' cap analog (beta-Se-ARCA D1) To Be Published
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5MMM
| Structure of the 70S chloroplast ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein 2, ... | 著者 | Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N. | 登録日 | 2016-12-11 | 公開日 | 2017-01-11 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The complete structure of the chloroplast 70S ribosome in complex with translation factor pY. EMBO J., 36, 2017
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5MA2
| PCE reductive dehalogenase from S. multivorans in complex with 4-iodophenol | 分子名称: | 4-IODOPHENOL, BENZAMIDINE, GLYCEROL, ... | 著者 | Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. | 登録日 | 2016-11-03 | 公開日 | 2017-07-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.879 Å) | 主引用文献 | Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
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5CD7
| Crystal structure of the NTD L199M of Drosophila Oskar protein | 分子名称: | GLYCEROL, Maternal effect protein oskar | 著者 | Yang, N, Hu, M, Yu, Z, Wang, M, Lehmann, R, Xu, R.M. | 登録日 | 2015-07-03 | 公開日 | 2015-09-02 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Structure of Drosophila Oskar reveals a novel RNA binding protein Proc.Natl.Acad.Sci.USA, 112, 2015
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5M7W
| Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2) | 分子名称: | Eukaryotic translation initiation factor 4E, GLYCEROL, [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl [phosphonooxy(sulfanyl)phosphoryl] hydrogen phosphate | 著者 | Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M. | 登録日 | 2016-10-28 | 公開日 | 2017-12-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Translation initiation factor 4E in complex with (SP)-m2(7,2'O)GppSpG mRNA 5' cap analog (beta-S-ARCA D2) To Be Published
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5C84
| Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 20 | 分子名称: | (2R,5R)-4-[2-(6-chloro-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-c]pyridin-1-yl)-2-oxoethyl]-5-(methoxymethyl)-2-methylpiperazin-1-ium, E3 ubiquitin-protein ligase XIAP, ZINC ION | 著者 | Chessari, G, Buck, I.M, Day, J.E.H, Day, P.J, Iqbal, A, Johnson, C.N, Lewis, E.J, Martins, V, Miller, D, Reader, M, Rees, D.C, Rich, S.J, Tamanini, E, Vitorino, M, Ward, G.A, Williams, P.A, Williams, G, Wilsher, N.E, Woolford, A.J.-A. | 登録日 | 2015-06-25 | 公開日 | 2015-08-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP. J.Med.Chem., 58, 2015
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5M91
| PCE reductive dehalogenase from S. multivorans in complex with 2,6-dibromophenol | 分子名称: | 2,6-bis(bromanyl)phenol, BENZAMIDINE, GLYCEROL, ... | 著者 | Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. | 登録日 | 2016-10-31 | 公開日 | 2017-07-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.719 Å) | 主引用文献 | Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
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8QP0
| A hexamer pore in the S-layer of Sulfolobus acidocaldarius formed by SlaA protein | 分子名称: | S-layer protein A | 著者 | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | 登録日 | 2023-09-29 | 公開日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | 主引用文献 | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius. Elife, 13, 2024
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5MGC
| STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 4-Galactosyl-lactose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Probable beta-galactosidase A, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | 登録日 | 2016-11-21 | 公開日 | 2017-04-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages. FEBS J., 284, 2017
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8QOX
| Two-component assembly of SlaA and SlaB S-layer proteins of Sulfolobus acidocaldarius | 分子名称: | Conserved membrane protein, S-layer protein A | 著者 | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | 登録日 | 2023-09-29 | 公開日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | 主引用文献 | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius. Elife, 13, 2024
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5CM1
| X-ray structure of perdeuterated TTR mutant - T119M at 1.22A | 分子名称: | Transthyretin | 著者 | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | 登録日 | 2015-07-16 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | X-ray structure of perdeuterated TTR mutant - T119M at 1.22A To Be Published
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5CMA
| Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment | 分子名称: | Antibody ch8H9 Fab heavy chain, Antibody ch8H9 Fab light chain | 著者 | Ahmed, M, Goldgur, Y, Cheng, M, Cheung, N.K. | 登録日 | 2015-07-16 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3. J.Biol.Chem., 290, 2015
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