8R7M

CTX-M14 in complex with boric acid and 1,2-diol boric ester

Summary for 8R7M

Entry DOI	10.2210/pdb8r7m/pdb
Descriptor	Beta-lactamase, BORIC ACID, GLYCEROL, ... (7 entities in total)
Functional Keywords	lactamase, hydrolase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	28671.67
Authors	Werner, N.,Prester, A.,Hinrichs, W.,Perbandt, M.,Betzel, C. (deposition date: 2023-11-26, release date: 2024-01-17, Last modification date: 2024-07-17)
Primary citation	Prester, A.,Perbandt, M.,Galchenkova, M.,Oberthuer, D.,Werner, N.,Henkel, A.,Maracke, J.,Yefanov, O.,Hakanpaa, J.,Pompidor, G.,Meyer, J.,Chapman, H.,Aepfelbacher, M.,Hinrichs, W.,Rohde, H.,Betzel, C. Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7:152-152, 2024 Cited by PubMed: 38969718 DOI: 10.1038/s42004-024-01236-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1 Å)

Structure validation