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PDB: 52230 件

8RG2
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BU of 8rg2 by Molmil
Structure of BlaC from Mycobacterium tuberculosis at pH 8
分子名称: Beta-lactamase, GLYCEROL
著者Sun, J, Bruenle, S, Ubbink, M.
登録日2023-12-13
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC.
Int.J.Biol.Macromol., 278, 2024
4QOE
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BU of 4qoe by Molmil
The value 'crystal structure of fad quinone reductase 2 at 1.45A
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Ribosyldihydronicotinamide dehydrogenase [quinone], ...
著者Serriere, J, Boutin, J.A, Isabet, T, Antoine, M, Ferry, G.
登録日2014-06-20
公開日2015-07-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The value 'crystal structure of fad quinone reductase 2 at 1.45A
To be Published
6IAH
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BU of 6iah by Molmil
Phosphatase Tt82 from Thermococcus thioreducens
分子名称: CHLORIDE ION, Hydrolase, MAGNESIUM ION
著者Havlickova, P, Brinsa, V, Brynda, J, Pachl, P, Prudnikova, T, Mesters, J.R, Kascakova, B, Kuty, M, Pusey, M.L, Ng, J.D, Rezacova, P, Smatanova, I.K.
登録日2018-11-26
公開日2019-08-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A novel structurally characterized haloacid dehalogenase superfamily phosphatase from Thermococcus thioreducens with diverse substrate specificity.
Acta Crystallogr D Struct Biol, 75, 2019
4QW3
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BU of 4qw3 by Molmil
yCP beta5-C63F mutant in complex with bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
8RCK
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BU of 8rck by Molmil
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.
分子名称: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L.
登録日2023-12-06
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.
To Be Published
4QPT
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BU of 4qpt by Molmil
Structural Investigation of hnRNP L
分子名称: Heterogenous nuclear ribonucleoprotein L, PHOSPHATE ION
著者Blatter, M, Allain, F.H.-T.
登録日2014-06-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein.
J.Mol.Biol., 427, 2015
4QQ5
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BU of 4qq5 by Molmil
Crystal Structure of FGF Receptor (FGFR) 4 Kinase Harboring the V550L Gate-Keeper Mutation in Complex With FIIN-2, an Irreversible Tyrosine Kinase Inhibitor Capable of Overcoming FGFR Kinase Gate-Keeper Mutations
分子名称: Fibroblast growth factor receptor 4, N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide
著者Huang, Z, Mohammadi, M.
登録日2014-06-26
公開日2014-10-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.203 Å)
主引用文献DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors.
Acs Chem.Biol., 10, 2015
8RJJ
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BU of 8rjj by Molmil
HCV E1/E2 homodimer complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, ...
著者Augestad, E.H, Olesen, C.H, Groenberg, C, Soerensen, A, Velazquez-Moctezuma, R, Fanalista, M, Bukh, J, Wang, K, Gourdon, P, Prentoe, J.
登録日2023-12-21
公開日2024-09-04
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献The hepatitis C virus envelope protein complex is a dimer of heterodimers.
Nature, 633, 2024
8ROA
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BU of 8roa by Molmil
Human cohesin SMC1A-HD(longCC-EQ)/RAD21-C complex - ADP-bound conformation
分子名称: 64-kDa C-terminal product, ADENOSINE-5'-DIPHOSPHATE, Structural maintenance of chromosomes protein 1A
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.4355 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8RCN
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BU of 8rcn by Molmil
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
分子名称: Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Anandapadamanaban, M, Hay, I.M, Perisic, O, Williams, R.L.
登録日2023-12-06
公開日2024-09-11
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
To Be Published
4QZ3
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BU of 4qz3 by Molmil
yCP beta5-A49V mutant in complex with the epoxyketone inhibitor ONX 0914
分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-27
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QUY
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BU of 4quy by Molmil
yCP beta5-A49S-mutant
分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ...
著者Huber, E.M, Heinemeyer, W, Groll, M.
登録日2014-07-14
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
8RO8
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BU of 8ro8 by Molmil
Human cohesin SMC1A-HD(longCC-EQ)/RAD21-C complex - Apo closed P-loop conformation
分子名称: 64-kDa C-terminal product, Structural maintenance of chromosomes protein 1A
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8RO9
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BU of 8ro9 by Molmil
Human cohesin SMC1A-HD(longCC-EQ)/RAD21-C complex - Open/closed P-loop conformation
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 64-kDa C-terminal product, Structural maintenance of chromosomes protein 1A
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.767 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROD
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BU of 8rod by Molmil
Human cohesin SMC1A-HD(shortCC-EQ)/RAD21-C complex - Open/closed P-loop conformation
分子名称: 64-kDa C-terminal product, SULFATE ION, Structural maintenance of chromosomes protein 1A
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROE
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BU of 8roe by Molmil
Human cohesin SMC1A-HD(shortCC-EQ)/RAD21-C complex - ADP-bound conformation
分子名称: 64-kDa C-terminal product, ADENOSINE-5'-DIPHOSPHATE, Structural maintenance of chromosomes protein 1A
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROF
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BU of 8rof by Molmil
Human cohesin SMC1A-HD(shortCC-EQ)/RAD21-C complex - ADP-Mg-bound conformation
分子名称: 64-kDa C-terminal product, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROI
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BU of 8roi by Molmil
Human cohesin SMC3-HD(EQ)/RAD21-N complex - ADP-bound conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, Double-strand-break repair protein rad21 homolog, Structural maintenance of chromosomes protein 3
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROL
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BU of 8rol by Molmil
Human cohesin SMC3-HD(EQ)/RAD21-N complex - ATP-Mg-bound conformation - Form 2
分子名称: Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
4R0T
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BU of 4r0t by Molmil
Crystal structure of P. aeruginosa TpbA (C132S) in complex with pTyr
分子名称: PHOSPHATE ION, Protein tyrosine phosphatase TpbA, TYROSINE
著者Xu, K, Li, S, Wang, Y, Bartlam, M.
登録日2014-08-01
公開日2015-05-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structural and Biochemical Analysis of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from the Opportunistic Pathogen Pseudomonas aeruginosa PAO1
Plos One, 10
8RX1
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BU of 8rx1 by Molmil
CryoEM structure of the gTuRC-CM1dim complex
分子名称: Actin b, CM1, Gamma-tubulin complex component 2, ...
著者Llorca, O, Serna, M, Gonzalez-Rodriguez, N.
登録日2024-02-06
公開日2024-09-25
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献CDK5RAP2 activates microtubule nucleator gamma TuRC by facilitating template formation and actin release.
Dev.Cell, 2024
8ROB
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BU of 8rob by Molmil
Human cohesin SMC1A-HD(longCC-EQ)/RAD21-C complex - ATPgS-Mg-bound conformation
分子名称: 64-kDa C-terminal product, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (2.5019 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROG
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BU of 8rog by Molmil
Human cohesin SMC1A-HD(shortCC-EQ)/RAD21-C complex - ATPgS-Mg-bound conformation
分子名称: 64-kDa C-terminal product, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-18
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROH
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BU of 8roh by Molmil
Human cohesin SMC3-HD(EQ)/RAD21-N complex - Apo conformation
分子名称: Double-strand-break repair protein rad21 homolog, GLYCEROL, SULFATE ION, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024
8ROJ
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BU of 8roj by Molmil
Human cohesin SMC3-HD/RAD21-N complex - ADP-Mg-bound conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ...
著者Vitoria Gomes, M, Romier, C.
登録日2024-01-11
公開日2024-09-11
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains.
Cell Rep, 43, 2024

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件を2024-11-06に公開中

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