8ROH

Human cohesin SMC3-HD(EQ)/RAD21-N complex - Apo conformation

Summary for 8ROH

Entry DOI	10.2210/pdb8roh/pdb
Descriptor	Structural maintenance of chromosomes protein 3, Double-strand-break repair protein rad21 homolog, SULFATE ION, ... (5 entities in total)
Functional Keywords	3d genome organization, chromatin, cohesin, atpase activity, atpase cycle, nuclear protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	67446.98
Authors	Vitoria Gomes, M.,Romier, C. (deposition date: 2024-01-11, release date: 2024-09-11, Last modification date: 2024-09-25)
Primary citation	Vitoria Gomes, M.,Landwerlin, P.,Diebold-Durand, M.L.,Shaik, T.B.,Durand, A.,Troesch, E.,Weber, C.,Brillet, K.,Lemee, M.V.,Decroos, C.,Dulac, L.,Antony, P.,Watrin, E.,Ennifar, E.,Golzio, C.,Romier, C. The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains. Cell Rep, 43:114656-114656, 2024 Cited by PubMed: 39240714 DOI: 10.1016/j.celrep.2024.114656 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation