8U5L
 
 | |
8GYR
 | | Crystal structure of a variable region segment of Leptospira host-interacting outer surface protein, LigA | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Kumar, P, Akif, M. | | 登録日 | 2022-09-23 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Crystal structure of a variable region segment of Leptospira host-interacting outer surface protein, LigA, reveals the orientation of Ig-like domains.
Int.J.Biol.Macromol., 244, 2023
|
|
8H1D
 | | Solid-state NMR Structure of Aquaporin Z in its Native Cellular Membranes | | 分子名称: | Aquaporin Z | | 著者 | Xie, H, Zhao, Y, Zhao, W, Chen, Y, Liu, M, Yang, J. | | 登録日 | 2022-10-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Solid-state NMR structure determination of a membrane protein in E. coli cellular inner membrane.
Sci Adv, 9, 2023
|
|
8H2I
 | | Near-atomic structure of five-fold averaged PBCV-1 capsid | | 分子名称: | MCPv1, MCPv2, MCPv3, ... | | 著者 | Shao, Q, Agarkova, I.V, Noel, E.A, Dunigan, D.D, Liu, Y, Wang, A, Guo, M, Xie, L, Zhao, X, Rossmann, M.G, Van Etten, J.L, Klose, T, Fang, Q. | | 登録日 | 2022-10-06 | | 公開日 | 2022-11-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Near-atomic, non-icosahedrally averaged structure of giant virus Paramecium bursaria chlorella virus 1.
Nat Commun, 13, 2022
|
|
6QYQ
 | | Crystal structure of human thymidylate synthase (hTS) variant R175C | | 分子名称: | CHLORIDE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, SULFATE ION, ... | | 著者 | Pozzi, C, Mangani, M. | | 登録日 | 2019-03-09 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors.
Molecules, 24, 2019
|
|
5YP4
 | | Crystal structure of dipeptidyl peptidase IV (DPP IV) with Lys-Pro from Pseudoxanthomonas mexicana WO24 | | 分子名称: | Dipeptidyl aminopeptidase 4, GLYCEROL, LYSINE, ... | | 著者 | Roppongi, S, Suzuki, Y, Tateoka, C, Fuimoto, M, Morisawa, S, Iizuka, I, Nakamura, A, Honma, N, Shida, Y, Ogasawara, W, Tanaka, N, Sakamoto, Y, Nonaka, T. | | 登録日 | 2017-11-01 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues.
Sci Rep, 8, 2018
|
|
5YQX
 | | Crystal Structure Analysis of the BRD4 | | 分子名称: | (2R)-2-(cyclopropylmethyl)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-4H-1,4-benzoxazin-3-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | | 著者 | Xue, X, Zhang, Y, Wang, C, Song, M. | | 登録日 | 2017-11-08 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.
Eur.J.Med.Chem., 152, 2018
|
|
8GZ5
 | | Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody P17, ... | | 著者 | Yamaguchi, K, Anzai, I, Maeda, R, Moriguchi, M, Watanabe, T, Imura, A, Takaori-Kondo, A, Inoue, T. | | 登録日 | 2022-09-25 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant.
J.Biochem., 173, 2023
|
|
8GZ6
 | | Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Nanobody P17 | | 著者 | Yamaguchi, K, Anzai, I, Maeda, R, Moriguchi, M, Watanabe, T, Imura, A, Takaori-Kondo, A, Inoue, T. | | 登録日 | 2022-09-25 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural insights into the rational design of a nanobody that binds with high affinity to the SARS-CoV-2 spike variant.
J.Biochem., 173, 2023
|
|
8H5E
 | | Crystal structure of the MgtE TM domain in complex with Ca2+ ions at 2.5 angstrom resolution | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, Magnesium transporter MgtE | | 著者 | Teng, X, Sheng, D, Hattori, M. | | 登録日 | 2022-10-13 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Ion selectivity mechanism of the MgtE channel for Mg 2+ over Ca 2 .
Iscience, 25, 2022
|
|
5YT9
 | |
3AGR
 | |
3OM9
 | |
7CLV
 | | Solution structure of mitochondrial Tim23 channel in complex with a signaling peptide | | 分子名称: | COX4 isoform 1, TIM23 isoform 1 | | 著者 | Zhou, S, Ruan, M.S, Li, Y.Y, Yang, J, Richter, C, Schwalbe, H, Shen, B, Wang, J.F. | | 登録日 | 2020-07-22 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide.
Cell Res., 31, 2021
|
|
8H99
 | | Crystal structure of E. coli ThrS catalytic domain mutant | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, IMIDAZOLE, MAGNESIUM ION, ... | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
|
|
8H9C
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 4 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
|
|
8HJB
 | |
8H98
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 1 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
|
|
8H9B
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 3 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
|
|
7CW3
 | | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | 登録日 | 2020-08-27 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8H1P
 | | Cryo-EM structure of the human RAD52 protein | | 分子名称: | DNA repair protein RAD52 homolog | | 著者 | Kinoshita, C, Takizawa, Y, Saotome, M, Ogino, S, Kurumizaka, H, Kagawa, W. | | 登録日 | 2022-10-03 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | The cryo-EM structure of full-length RAD52 protein contains an undecameric ring.
Febs Open Bio, 13, 2023
|
|
8GYH
 | | Crystal structure of Fic25 (apo form) from Streptomyces ficellus | | 分子名称: | DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, IMIDAZOLE | | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | | 登録日 | 2022-09-22 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis.
Acs Chem.Biol., 18, 2023
|
|
8H9A
 | | Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | | 分子名称: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | | 著者 | Qiao, H, Xia, M, Wang, J, Fang, P. | | 登録日 | 2022-10-25 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion.
Commun Biol, 6, 2023
|
|
7COI
 | | Crystal structure of the b-carbonic anhydrase CafA of the fungal pathogen Aspergillus fumigatus | | 分子名称: | ACETATE ION, Carbonic anhydrase, ZINC ION | | 著者 | Jin, M.S, Kim, S, Yeon, J, Sung, J. | | 登録日 | 2020-08-04 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of beta-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus .
Mol.Cells, 43, 2020
|
|
8H70
 | |
