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PDB: 52259 件

3ZD5
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THE 2.2 A STRUCTURE OF A FULL-LENGTH CATALYTICALLY ACTIVE HAMMERHEAD RIBOZYME
分子名称: HAMMERHEAD RIBOZYME, ENZYME STRAND, SUBSTRATE STRAND
著者Martick, M, Scott, W.G.
登録日2012-11-24
公開日2012-12-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Tertiary contacts distant from the active site prime a ribozyme for catalysis.
Cell, 126, 2006
3ZY2
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Crystal structure of POFUT1 in complex with GDP (High resolution dataset)
分子名称: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PUTATIVE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1
著者Lira-Navarrete, E, Valero-Gonzalez, J, Villanueva, R, Martinez-Julvez, M, Tejero, T, Merino, P, Panjikar, S, Hurtado-Guerrero, R.
登録日2011-08-17
公開日2011-09-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural Insights Into the Mechanism of Protein O-Fucosylation.
Plos One, 6, 2011
1GSI
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE COMPLEXED WITH THYMIDINE MONOPHOSPHATE (TMP)
分子名称: ACETATE ION, MAGNESIUM ION, SULFATE ION, ...
著者Ursby, T, Weik, M, Fioravanti, E, Delarue, M, Goeldner, M, Bourgeois, D.
登録日2002-01-03
公開日2002-03-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cryophotolysis of Caged Compounds: A Technique for Trapping Intermediate States in Protein Crystals
Acta Crystallogr.,Sect.D, 58, 2002
3ZXJ
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Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, HIAXHD3, ...
著者McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J.
登録日2011-08-11
公開日2012-04-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
3ZX7
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Complex of lysenin with phosphocholine
分子名称: LYSENIN, PHOSPHATE ION, PHOSPHOCHOLINE, ...
著者De Colibus, L, Sonnen, A.F.P, Morris, K.J, Siebert, C.A, Abrusci, P, Plitzko, J, Hodnik, V, Leippe, M, Volpi, E, Anderluh, G, Gilbert, R.J.C.
登録日2011-08-08
公開日2012-09-19
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition.
Structure, 20, 2012
3ZHC
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Structure of the phytase from Citrobacter braakii at 2.3 angstrom resolution.
分子名称: CHLORIDE ION, FORMIC ACID, PHYTASE
著者Wilson, K.S, Ariza, A, Sanchez-Romero, I, Skjot, M, Vind, J, DeMaria, L, Skov, L.K, Sanchez-Ruiz, J.M.
登録日2012-12-20
公開日2013-08-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks
Plos One, 8, 2013
3ZUZ
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Structure of Shq1p C-terminal domain
分子名称: ISOPROPYL ALCOHOL, PROTEIN SHQ1
著者Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N.
登録日2011-07-22
公開日2011-11-30
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
1FBZ
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Structure-based design of a novel, osteoclast-selective, nonpeptide Src SH2 inhibitor with in vivo anti-resorptive activity
分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK, {4-[2-ACETYLAMINO-2-(3-CARBAMOYL-2-CYCLOHEXYLMETHOXY-6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTEN-5YLCARBAMOYL)-ETHYL]-2-PHOSPHONO-PHENYL}-PHOSPHONIC ACID
著者Shakespeare, W, Yang, M, Bohacek, R, Cerasoli, F, Stebbis, K, Sundaramoorthi, R, Vu, C, Pradeepan, S, Metcalf, C, Haraldson, C, Merry, T, Dalgarno, D, Narula, S, Hatada, M, Lu, X, Van Schravendijk, M.R, Adams, S, Violette, S, Smith, J, Guan, W, Bartlett, C, Herson, J, Iuliucci, J, Weigele, M, Sawyer, T.
登録日2000-07-17
公開日2000-08-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design of an osteoclast-selective, nonpeptide src homology 2 inhibitor with in vivo antiresorptive activity.
Proc.Natl.Acad.Sci.Usa, 97, 2000
409D
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CRYSTAL STRUCTURE OF AN RNA R(CCCIUGGG) WITH THREE INDEPENDENT DUPLEXES INCORPORATING TANDEM I.U WOBBLES
分子名称: RNA (5'-R(*CP*CP*CP*IP*UP*GP*GP*G)-3')
著者Pan, B, Mitra, S.N, Sun, L, Hart, D, Sundaralingam, M.
登録日1998-06-26
公開日1999-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of an RNA octamer duplex r(CCCIUGGG)2 incorporating tandem I.U wobbles.
Nucleic Acids Res., 26, 1998
418D
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5'-R(*GP*UP*GP*CP*AP*CP*A)-D(P*C)-3'
分子名称: RNA (5'-R(*GP*UP*GP*CP*AP*CP*AP*C)-3')
著者Mitra, S.N, Biswas, R, Shi, K, Sundaralingam, M.
登録日1998-08-12
公開日2003-06-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an RNA duplex [r(gugcaca)dC]2 with 3'-dinucleoside overhangs forming a superhelix.
J.Biomol.Struct.Dyn., 11, 2000
4A2M
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Structure of the periplasmic domain of the heparin and heparan sulphate sensing hybrid two component system BT4663 in apo and ligand bound forms
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, TWO-COMPONENT SYSTEM SENSOR HISTIDINE KINASE/RESPONSE
著者Lowe, E.C, Basle, A, Czjzek, M, Firbank, S.J, Bolam, D.N.
登録日2011-09-27
公開日2012-05-02
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献A Scissor Blade-Like Closing Mechanism Implicated in Transmembrane Signaling in a Bacteroides Hybrid Two-Component System.
Proc.Natl.Acad.Sci.USA, 109, 2012
4A93
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RNA Polymerase II elongation complex containing a CPD Lesion
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ...
著者Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M.
登録日2011-11-23
公開日2012-03-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
1QKK
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Crystal structure of the receiver domain and linker region of DctD from Sinorhizobium meliloti
分子名称: C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN
著者Meyer, M.G, Park, S, Zeringue, L, Staley, M, Mckinstry, M, Kaufman, R.I, Zhang, H, Yan, D, Yennawar, N, Farber, G.K, Nixon, B.T.
登録日1999-07-23
公開日2000-07-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A dimeric two-component receiver domain inhibits the sigma54-dependent ATPase in DctD.
Faseb J., 15, 2001
410D
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DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE
分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'), SPERMINE
著者Tereshko, V, Portmann, S, Tay, E.C, Martin, P, Natt, F, Altmann, K.H, Egli, M.
登録日1998-06-30
公開日1998-07-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues.
Biochemistry, 37, 1998
4YYC
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Crystal structure of trimethylamine methyltransferase from Sinorhizobium meliloti in complex with unknown ligand
分子名称: CHLORIDE ION, Putative trimethylamine methyltransferase, UNKNOWN LIGAND
著者Shabalin, I.G, Porebski, P.J, Gasiorowska, O.A, Handing, K.B, Niedzialkowska, E, Cymborowski, M.T, Cooper, D.R, Stead, M, Hammonds, J, Ahmed, M, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
登録日2015-03-23
公開日2015-04-08
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Protein purification and crystallization artifacts: The tale usually not told.
Protein Sci., 25, 2016
437D
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CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING
分子名称: MAGNESIUM ION, RNA PSEUDOKNOT, SODIUM ION
著者Su, L, Chen, L, Egli, M, Berger, J.M, Rich, A.
登録日1998-11-24
公開日1998-12-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot.
Nat.Struct.Biol., 6, 1999
4YYQ
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Ficin A
分子名称: Ficin isoform A
著者Azarkan, M, Baeyens-Volant, D, Loris, R.
登録日2015-03-24
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Crystal structure of four variants of the protease Ficin from the common fig
To Be Published
4A6L
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beta-tryptase inhibitor
分子名称: 1-{3-[1-({5-[(2-fluorophenyl)ethynyl]furan-2-yl}carbonyl)piperidin-4-yl]phenyl}methanamine, TRYPTASE ALPHA/BETA-1
著者Mathieu, M, Maignan, S.
登録日2011-11-04
公開日2012-01-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure-Based Library Design and the Discovery of a Potent and Selective Mast Cell Beta-Tryptase Inhibitor as an Oral Therapeutic Agent.
Bioorg.Med.Chem.Lett., 22, 2012
4AC7
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The crystal structure of Sporosarcina pasteurii urease in complex with citrate
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, HYDROXIDE ION, ...
著者Benini, S, Kosikowska, P, Cianci, M, Gonzalez Vara, A, Berlicki, L, Ciurli, S.
登録日2011-12-14
公開日2013-01-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Crystal Structure of Sporosarcina Pasteurii Urease in a Complex with Citrate Provides New Hints for Inhibitor Design.
J.Biol.Inorg.Chem., 18, 2013
3DHJ
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Beta 2 microglobulin mutant W60C
分子名称: Beta-2-microglobulin
著者Ricagno, S, Colombo, M, de Rosa, M, Bolognesi, M, Giorgetti, S, Bellotti, V.
登録日2008-06-18
公開日2008-11-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DE loop mutations affect beta2-microglobulin stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 377, 2008
4A27
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Crystal structure of human synaptic vesicle membrane protein VAT-1 homolog-like protein
分子名称: 1,2-ETHANEDIOL, SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE
著者Vollmar, M, Shafqat, N, Muniz, J.R.C, Krojer, T, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Yue, W.W, Oppermann, U.
登録日2011-09-22
公開日2011-10-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Human Synaptic Vesicle Membrane Protein Vat-1 Homolog-Like Protein
To be Published
4Z0H
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X-ray structure of cytoplasmic glyceraldehyde-3-phosphate dehydrogenase (GapC1) complexed with NAD
分子名称: Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Fermani, S, Zaffagnini, M, Orru, R, Falini, G, Trost, P.
登録日2015-03-26
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tuning Cysteine Reactivity and Sulfenic Acid Stability by Protein Microenvironment in Glyceraldehyde-3-Phosphate Dehydrogenases of Arabidopsis thaliana.
Antioxid. Redox Signal., 24, 2016
4A0O
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Symmetry-free cryo-EM map of TRiC in the nucleotide-free (apo) state
分子名称: T-COMPLEX PROTEIN 1 SUBUNIT BETA
著者Cong, Y, Schroder, G.F, Meyer, A.S, Jakana, J, Ma, B, Dougherty, M.T, Schmid, M.F, Reissmann, S, Levitt, M, Ludtke, S.L, Frydman, J, Chiu, W.
登録日2011-09-10
公開日2012-02-15
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (10.5 Å)
主引用文献Symmetry-Free Cryo-Em Structures of the Chaperonin Tric Along its ATPase-Driven Conformational Cycle.
Embo J., 31, 2012
4NPX
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Structure of hypothetical protein Cj0539 from Campylobacter jejuni
分子名称: Putative uncharacterized protein
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Adkins, J.N, Endres, M, Nissen, M, Konkel, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2013-11-22
公開日2014-01-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of hypothetical protein Cj0539 from Campylobacter jejuni
To be Published
1QT9
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OXIDIZED [2FE-2S] FERREDOXIN FROM ANABAENA PCC7119
分子名称: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I
著者Morales, R, Chron, M.-H, Hudry-Clergeon, G, Petillot, Y, Norager, S, Medina, M, Frey, M.
登録日1999-07-01
公開日1999-12-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Refined X-ray structures of the oxidized, at 1.3 A, and reduced, at 1.17 A, [2Fe-2S] ferredoxin from the cyanobacterium Anabaena PCC7119 show redox-linked conformational changes.
Biochemistry, 38, 1999

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