4GHM
| Crystal Structure of the H233A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0 | 分子名称: | 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2012-08-08 | 公開日 | 2012-09-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.618 Å) | 主引用文献 | Crystal Structure of the H233A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0 To be Published
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1UCV
| Sterile alpha motif (SAM) domain of ephrin type-A receptor 8 | 分子名称: | EPHRIN TYPE-A RECEPTOR 8 | 著者 | Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-04-23 | 公開日 | 2004-05-11 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Sterile alpha motif (SAM) domain of ephrin type-A receptor 8 To be Published
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4GER
| Crystal structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa | 分子名称: | CALCIUM ION, Gentlyase metalloprotease, LYSINE, ... | 著者 | Ruf, A, Stihle, M, Benz, J, Schmidt, M, Sobek, H. | 登録日 | 2012-08-02 | 公開日 | 2013-01-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Structure of Gentlyase, the neutral metalloprotease of Paenibacillus polymyxa. Acta Crystallogr.,Sect.D, 69, 2013
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1TS4
| Q139K MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS | 分子名称: | TOXIC SHOCK SYNDROME TOXIN-1 | 著者 | Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H. | 登録日 | 1997-10-10 | 公開日 | 1998-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity. Biochemistry, 37, 1998
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1TXM
| SCORPION TOXIN (MAUROTOXIN) FROM SCORPIO MAURUS, NMR, 35 STRUCTURES | 分子名称: | MAUROTOXIN | 著者 | Blanc, E, Sabatier, J.-M, Kharrat, R, Meunier, S, El Ayeb, M, Van Rietschoten, J, Darbon, H. | 登録日 | 1996-11-19 | 公開日 | 1997-06-05 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels. Proteins, 29, 1997
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7JM6
| Structure of chicken CLC-7 | 分子名称: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Schrecker, M, Hite, R. | 登録日 | 2020-07-31 | 公開日 | 2020-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. Elife, 9, 2020
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7JMP
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-39 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-39 heavy chain, COVA2-39 light chain, ... | 著者 | Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A. | 登録日 | 2020-08-02 | 公開日 | 2020-08-26 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.712 Å) | 主引用文献 | An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain. Cell Rep, 33, 2020
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7K17
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7JRO
| Plant Mitochondrial complex IV from Vigna radiata | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, CARDIOLIPIN, ... | 著者 | Maldonado, M, Letts, J.A. | 登録日 | 2020-08-12 | 公開日 | 2021-01-20 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Atomic structures of respiratory complex III 2 , complex IV, and supercomplex III 2 -IV from vascular plants. Elife, 10, 2021
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1TMO
| TRIMETHYLAMINE N-OXIDE REDUCTASE FROM SHEWANELLA MASSILIA | 分子名称: | GUANYLATE-O'-PHOSPHORIC ACID MONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,5,6,7,8A,9,10,10A-OCTAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL) ESTER, MOLYBDENUM (IV)OXIDE, TRIMETHYLAMINE N-OXIDE REDUCTASE | 著者 | Czjzek, M, Dos Santos, J.P, Giordano, G, Mejean, V. | 登録日 | 1998-08-03 | 公開日 | 1999-03-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of oxidized trimethylamine N-oxide reductase from Shewanella massilia at 2.5 A resolution. J.Mol.Biol., 284, 1998
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5A0G
| N-terminal thioester domain of surface protein from Clostridium perfringens | 分子名称: | SURFACE ANCHORED PROTEIN | 著者 | Walden, M, Edwards, J.M, Dziewulska, A.M, Kan, S.-Y, Schwarz-Linek, U, Banfield, M.J. | 登録日 | 2015-04-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | An internal thioester in a pathogen surface protein mediates covalent host binding. Elife, 4, 2015
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7JN2
| The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441 inhibitor | 分子名称: | 3-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide, ACETATE ION, CHLORIDE ION, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Lisnyak, V, Maki, S, Taylor, C, Zhang, Y, Zhou, Z, Azizi, S.A, Jones, K, Kathayat, R, Snyder, S.A, Dickinson, B.C, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-08-03 | 公開日 | 2020-08-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | The crystal structure of Papain-Like Protease of SARS CoV-2 in complex with PLP_Snyder441 to be published
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4GJ8
| Crystal structure of renin in complex with PKF909-724 (compound 3) | 分子名称: | (2R)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol, (2S)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ostermann, N, Zink, F, Kroemer, M. | 登録日 | 2012-08-09 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
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4GJD
| Crystal structure of renin in complex with NVP-BGQ311 (compound 12) | 分子名称: | (3S,5R)-N-{[9-(4-methoxybutyl)-9H-xanthen-9-yl]methyl}-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... | 著者 | Ostermann, N, Zink, F, Kroemer, M. | 登録日 | 2012-08-09 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
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2X5U
| 80 microsecond Laue diffraction snapshot from crystals of a photosynthetic reaction centre without illumination. | 分子名称: | BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, FE (II) ION, ... | 著者 | Wohri, A.B, Katona, G, Johansson, L.C, Fritz, E, Malmerberg, E, Andersson, M, Vincent, J, Eklund, M, Cammarata, M, Wulff, M, Davidsson, J, Groenhof, G, Neutze, R. | 登録日 | 2010-02-10 | 公開日 | 2010-05-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Light-induced structural changes in a photosynthetic reaction center caught by Laue diffraction. Science, 328, 2010
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7K3R
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1TYN
| ATOMIC STRUCTURE OF THE TRYPSIN-CYCLOTHEONAMIDE A COMPLEX: LESSONS FOR THE DESIGN OF SERINE PROTEASE INHIBITORS | 分子名称: | BETA-TRYPSIN, CYCLOTHEONAMIDE A | 著者 | Lee, A.Y, Hagihara, M, Karmacharya, R, Albers, M.W, Schreiber, S.L, Clardy, J. | 登録日 | 1994-09-19 | 公開日 | 1995-01-26 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Atomic Structure of the Trypsin-Cyclotheonamide a Complex: Lessons for the Design of Serine Protease Inhibitors J.Am.Chem.Soc., 115, 1993
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2X5F
| Crystal structure of the methicillin-resistant Staphylococcus aureus Sar2028, an aspartate_tyrosine_phenylalanine pyridoxal-5'-phosphate dependent aminotransferase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ASPARTATE_TYROSINE_PHENYLALANINE PYRIDOXAL-5' PHOSPHATE-DEPENDENT AMINOTRANSFERASE, MAGNESIUM ION, ... | 著者 | Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H. | 登録日 | 2010-02-08 | 公開日 | 2010-07-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Scottish Structural Proteomics Facility: Targets, Methods and Outputs. J.Struct.Funct.Genom., 11, 2010
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1MLX
| Crystal Structure Analysis of a 2'-O-[2-(Methylthio)-ethyl]-Modified Oligodeoxynucleotide Duplex | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*SMTP*AP*CP*GP*C)-3' | 著者 | Prakash, T.P, Manoharan, M, Kawasaki, A.M, Fraser, A.S, Lesnik, E.A, Sioufi, N, Leeds, J.M, Teplova, M, Egli, M. | 登録日 | 2002-08-31 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | 2'-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2'-O-[2-(Methoxy)-ethyl]-Modified
Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA Biochemistry, 41, 2002
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1UHM
| Solution structure of the globular domain of linker histone homolog Hho1p from S. cerevisiae | 分子名称: | Histone H1 | 著者 | Ono, K, Kusano, O, Shimotakahara, S, Shimizu, M, Yamazaki, T, Shindo, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-07-05 | 公開日 | 2003-12-16 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy. Nucleic Acids Res., 31, 2003
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7KB0
| O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima with pyridoxal-5-phosphate (PLP) bound in the internal aldimine state | 分子名称: | O-acetyl-L-homoserine sulfhydrylase | 著者 | Brewster, J.L, Pachl, P, Squire, C, Selmer, M, Patrick, W.M. | 登録日 | 2020-10-01 | 公開日 | 2021-06-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis. J.Biol.Chem., 296, 2021
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4GPH
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7KB1
| Complex of O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima and a key reaction intermediate | 分子名称: | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, MAGNESIUM ION, O-acetyl-L-homoserine sulfhydrylase, ... | 著者 | Brewster, J.L, Pachl, P, Squire, C, Selmer, M, Patrick, W.M. | 登録日 | 2020-10-01 | 公開日 | 2021-06-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis. J.Biol.Chem., 296, 2021
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2W1I
| Structure determination of Aurora Kinase in complex with inhibitor | 分子名称: | 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM, JAK2 | 著者 | Howard, S, Berdini, V, Boulstridge, J.A, Carr, M.G, Cross, D.M, Curry, J, Devine, L.A, Early, T.R, Fazal, L, Gill, A.L, Heathcote, M, Maman, S, Matthews, J.E, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Rees, D.C, Reule, M, Tisi, D, Williams, G, Vinkovic, M, Wyatt, P.G. | 登録日 | 2008-10-17 | 公開日 | 2009-01-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity. J.Med.Chem., 52, 2009
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4GPC
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