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PDB: 51787 件

4ER3
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Crystal Structure of Human DOT1L in complex with inhibitor EPZ004777
分子名称: 1,2-ETHANEDIOL, 7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Histone-lysine N-methyltransferase, ...
著者Wernimont, A.K, Tempel, W, Yu, W, Scopton, A, Li, Y, Nguyen, K.T, Federation, A, Marineau, J, Qi, J, Vedadi, M, Bradner, J.E, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Brown, P.J, Structural Genomics Consortium (SGC)
登録日2012-04-19
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Nat Commun, 3, 2012
3WKF
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Crystal structure of cellobiose 2-epimerase
分子名称: CHLORIDE ION, Cellobiose 2-epimerase, PHOSPHATE ION
著者Fujiwara, T, Saburi, W, Tanaka, I, Yao, M.
登録日2013-10-21
公開日2013-12-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.743 Å)
主引用文献Structural Insights into the Epimerization of beta-1,4-Linked Oligosaccharides Catalyzed by Cellobiose 2-Epimerase, the Sole Enzyme Epimerizing Non-anomeric Hydroxyl Groups of Unmodified Sugars
J.Biol.Chem., 289, 2014
3WN0
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Crystal Structure of Streptomyces coelicolor alpha-L-arabinofuranosidase in complex with L-arabinose
分子名称: CALCIUM ION, CHLORIDE ION, CITRIC ACID, ...
著者Fujimoto, Z, Maehara, T, Ichinose, H, Michikawa, M, Harazono, K, Kaneko, S.
登録日2013-11-29
公開日2014-02-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and characterization of the glycoside hydrolase family 62 alpha-L-arabinofuranosidase from Streptomyces coelicolor
J.Biol.Chem., 289, 2014
3WI4
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Crystal structure of wild-type PorB from Neisseria meningitidis serogroup B
分子名称: Major outer membrane protein P.IB
著者Kattner, C, Toussi, D, Wetzler, L.M, Ruppel, N, Massari, P, Tanabe, M.
登録日2013-09-05
公開日2014-01-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition.
J.Struct.Biol., 185, 2014
2L38
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R29Q Sticholysin II mutant
分子名称: Sticholysin-2
著者Castrillo, I, Alegre-Cebollada, J, Martinez-del-Pozo, A, Gavilanes, J, Bruix, M.
登録日2010-09-10
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Structure of StnIIR29Q, a defective lipid binding mutant of the sea anemone actinoporin Sticholysin II
To be Published
2LHW
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Tri-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide
著者Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D.
登録日2011-08-18
公開日2012-04-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Deciphering structural elements of mucin glycoprotein recognition.
Acs Chem.Biol., 7, 2012
2LI2
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Mono-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MUC2 Mucin Domain Peptide
著者Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D.
登録日2011-08-18
公開日2012-04-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Deciphering structural elements of mucin glycoprotein recognition.
Acs Chem.Biol., 7, 2012
2L4X
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Solution Structure of apo-IscU(WT)
分子名称: Iron-sulfur cluster assembly scaffold protein
著者Kim, J.H, Tonelli, M, Markley, J.L.
登録日2010-10-19
公開日2011-12-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Three-Dimensional Structure and Determinants of Stability of the Iron-Sulfur Cluster Scaffold Protein IscU from Escherichia coli.
Biochemistry, 51, 2012
2LQI
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NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation)
分子名称: CREB-binding protein, Forkhead box O3
著者Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M.
登録日2012-03-06
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
2LR4
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NMR structure of the protein NP_390037.1 from Bacillus subtilis
分子名称: SPBc2 prophage-derived uncharacterized protein yolA
著者Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2012-03-22
公開日2012-05-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the protein NP_390037.1 from Bacillus subtilis
To be Published
2LRN
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Solution structure of a thiol:disulfide interchange protein from Bacteroides sp.
分子名称: Thiol:disulfide interchange protein
著者Harris, R, Bandaranayake, A.D, Banu, R, Bonanno, J.B, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chaparro, R, Evans, B, Garforth, S, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Lim, S, Love, J, Matikainen, B, Patel, H, Seidel, R.D, Smith, B, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-04-10
公開日2012-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of a thiol:disulfide interchange protein from Bacteroides sp.
To be Published
1UFX
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Solution structure of the third PDZ domain of human KIAA1526 protein
分子名称: KIAA1526 protein
著者Tochio, N, Kobayashi, N, Koshiba, S, Kigawa, T, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Matsuo, Y, Ohara, O, Nagase, T, Kikuno, R, Nakayama, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-06-10
公開日2003-12-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the third PDZ domain of human KIAA1526 protein
To be Published
2LST
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Solution structure of a thioredoxin from Thermus thermophilus
分子名称: Thioredoxin
著者Harris, R, Bandaranayake, A.D, Banu, R, Bonanno, J.B, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chaparro, R, Evans, B, Garforth, S, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Lim, S, Love, J, Matikainen, B, Patel, H, Seidel, R.D, Smith, B, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
登録日2012-05-04
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of a thioredoxin from Thermus thermophilus
To be Published
2L8M
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Reduced and CO-bound cytochrome P450cam (CYP101A1)
分子名称: CAMPHOR, CARBON MONOXIDE, CHLORIDE ION, ...
著者Pochapsky, T.C, Pochapsky, S.S, Dang, M, Asciutto, E, Madura, J.
登録日2011-01-19
公開日2011-02-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Experimentally Restrained Molecular Dynamics Simulations for Characterizing the Open States of Cytochrome P450(cam).
Biochemistry, 50, 2011
3WHO
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X-ray-Crystallographic Structure of an RNase Po1 Exhibiting Anti-tumor Activity
分子名称: Guanyl-specific ribonuclease Po1
著者Kobayashi, H, Katsurtani, T, Hara, Y, Motoyoshi, N, Itagaki, T, Akita, F, Higashiura, A, Yamada, Y, Suzuki, M, Inokuchi, N.
登録日2013-08-30
公開日2014-07-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献X-ray crystallographic structure of RNase Po1 that exhibits anti-tumor activity.
Biol.Pharm.Bull., 37, 2014
3WR2
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RNase Po1 complexed with 3'GMP
分子名称: GUANOSINE-3'-MONOPHOSPHATE, Guanyl-specific ribonuclease Po1
著者Hara, Y, Katsutani, T, Kobayashi, H, Suzuki, M.
登録日2014-02-13
公開日2015-02-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献RNase Po1 complexed with 3'GMP
to be published
2LM8
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Structure, Activity and Interactions of the Cysteine Deleted Analog of Tachyplesin-1 with Lipopolysaccharide Micelles
分子名称: CDT-LPS
著者Joshi, M, Bhattacharjya, S, Saravanan, R.
登録日2011-11-25
公開日2012-04-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure, activity and interactions of the cysteine deleted analog of tachyplesin-1 with lipopolysaccharide micelle: Mechanistic insights into outer-membrane permeabilization and endotoxin neutralization.
Biochim.Biophys.Acta, 1818, 2012
2LBH
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Solution Structure of the Dimeric Form of a Unliganded Bovine Neurophysin, Minimized Average Structure
分子名称: Neurophysin 1
著者Lee, H, Naik, M, Nguyen, T, Bracken, C, Breslow, E.
登録日2011-03-31
公開日2012-04-04
実験手法SOLUTION NMR
主引用文献Structural Basis of the Dimerization-Induced Increase in Neurophysin-Hormone Affinity: Interplay of Inter-Domain and Inter-Subunit Interactions
To be Published
3WY2
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Crystal structure of alpha-glucosidase in complex with glucose
分子名称: Alpha-glucosidase, GLYCEROL, MAGNESIUM ION, ...
著者Shen, X, Gai, Z, Kato, K, Yao, M.
登録日2014-08-18
公開日2015-06-10
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.471 Å)
主引用文献Structural analysis of the alpha-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
3WZ1
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Catalytic domain of beta-agarase from Microbulbifer thermotolerans JAMB-A94
分子名称: Agarase, GLYCEROL, SODIUM ION
著者Takagi, E, Hatada, Y, Akita, M, Ohta, Y, Yokoi, G, Miyazaki, T, Nishikawa, A, Tonozuka, T.
登録日2014-09-12
公開日2014-11-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the catalytic domain of a GH16 beta-agarase from a deep-sea bacterium, Microbulbifer thermotolerans JAMB-A94
Biosci.Biotechnol.Biochem., 79, 2015
3X0D
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Crystal structure of C.elegans PRMT7 in complex with SAH (P43212)
分子名称: Protein arginine N-methyltransferase 7, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Hasegawa, M, Toma-Fukai, S, Shimizu, T.
登録日2014-10-10
公開日2014-10-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Protein arginine methyltransferase 7 has a novel homodimer-like structure formed by tandem repeats
Febs Lett., 588, 2014
3X3Y
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Copper amine oxidase from Arthrobacter globiformis anaerobically reduced by histamine
分子名称: COPPER (II) ION, GLYCEROL, POTASSIUM ION, ...
著者Okajima, T, Nakanishi, S, Murakawa, T, Kataoka, M, Hayashi, H, Hamaguchi, A, Nakai, T, Kawano, Y, Yamaguchi, H, Tanizawa, K.
登録日2015-03-10
公開日2015-08-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.499 Å)
主引用文献Probing the Catalytic Mechanism of Copper Amine Oxidase from Arthrobacter globiformis with Halide Ions.
J.Biol.Chem., 290, 2015
3WY9
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Crystal structure of a complex of the archaeal ribosomal stalk protein aP1 and the GDP-bound archaeal elongation factor aEF1alpha
分子名称: 50S ribosomal protein L12, Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE
著者Ito, K, Honda, T, Suzuki, T, Miyoshi, T, Murakami, R, Yao, M, Uchiumi, T.
登録日2014-08-22
公開日2014-12-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular insights into the interaction of the ribosomal stalk protein with elongation factor 1 alpha.
Nucleic Acids Res., 42, 2014
3WY6
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Structure of hyperthermophilic family 12 endocellulase (E197A) from Pyrococcus furiosus in complex with laminaribiose
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, Endoglucanase A, ...
著者Kataoka, M, Ishikawa, K.
登録日2014-08-20
公開日2015-09-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of hyperthermophilic family 12 endocellulase (E197A) from Pyrococcus furiosus in complex with laminaribiose
To be Published
2LKJ
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Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails
分子名称: Integrin alpha-M
著者Chua, G.L, Tang, X.Y, Amalraj, M, Tan, S.M, Bhattacharjya, S.
登録日2011-10-12
公開日2011-11-02
最終更新日2011-11-16
実験手法SOLUTION NMR
主引用文献Structures and interaction analyses of the integrin alphaMbeta2 cytoplasmic tails
J.Biol.Chem., 2011

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