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PDB: 52259 件

4I2H
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Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(P*AP*AP*AP*AP*A)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA nucleotidylexotransferase, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
4I86
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Crystal structure of PilZ domain of CeSA from cellulose synthesizing bacterium
分子名称: Cellulose synthase 1
著者Fujiwara, T, Komoda, K, Sakurai, N, Tanaka, I, Yao, M.
登録日2012-12-03
公開日2013-04-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献The c-di-GMP recognition mechanism of the PilZ domain of bacterial cellulose synthase subunit A
Biochem.Biophys.Res.Commun., 431, 2013
2AEG
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X-Ray Crystal Structure of Protein Atu5096 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium Target AtR63.
分子名称: hypothetical protein AGR_pAT_140
著者Forouhar, F, Abashidze, M, Kuzin, A.P, Vorobiev, S.M, Shastry, R, Cooper, B, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2005-07-22
公開日2005-08-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Hypothetical Protein Atu5096 from Agrobacterium tumefaciens.
To be Published
3OIP
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Crystal structure of Yeast telomere protein Cdc13 OB1
分子名称: Cell division control protein 13
著者Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M.
登録日2010-08-19
公開日2010-11-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
4I53
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Crystal structure of clade C1086 HIV-1 gp120 core in complex with DMJ-II-121
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, HIV-1 glycoprotein, ...
著者Le-Khac, M, Hendrickson, W.A.
登録日2012-11-28
公開日2013-05-29
最終更新日2021-05-26
実験手法X-RAY DIFFRACTION (2.5002 Å)
主引用文献Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.
ACS Med Chem Lett, 4, 2013
2AG0
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Crystal structure of Benzaldehyde lyase (BAL)- native
分子名称: MAGNESIUM ION, THIAMINE DIPHOSPHATE, benzaldehyde lyase
著者Mosbacher, T.G, Mueller, M, Schulz, G.E.
登録日2005-07-26
公開日2006-01-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens
Febs J., 272, 2005
2WP1
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Structure of Brdt bromodomain 2 bound to an acetylated histone H3 peptide
分子名称: BROMODOMAIN TESTIS-SPECIFIC PROTEIN, HISTONE H3
著者Moriniere, J, Rousseaux, S, Steuerwald, U, Soler-Lopez, M, Curtet, S, Vitte, A.-L, Govin, J, Gaucher, J, Sadoul, K, Hart, D.J, Krijgsveld, J, Khochbin, S, Mueller, C.W, Petosa, C.
登録日2009-08-02
公開日2009-09-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cooperative Binding of Two Acetylation Marks on a Histone Tail by a Single Bromodomain.
Nature, 461, 2009
2WW4
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a triclinic crystal form of E. coli 4-diphosphocytidyl-2C-methyl-D- erythritol kinase
分子名称: 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL
著者Kalinowska-Tluscik, J, Miallau, L, Gabrielsen, M, Leonard, G.A, McSweeney, S.M, Hunter, W.N.
登録日2009-10-21
公開日2010-03-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Triclinic Crystal Form of Escherichia Coli 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase and Reassessment of the Quaternary Structure.
Acta Crystallogr.,Sect.F, 66, 2010
4I19
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The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
分子名称: ACETATE ION, Epoxide hydrolase, FORMIC ACID
著者Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2012-11-20
公開日2012-12-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
To be Published
3OJ2
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Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation
分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION
著者Beenken, A, Mohammadi, M.
登録日2010-08-20
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012
4I2E
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BU of 4i2e by Molmil
Ternary complex of mouse TdT with ssDNA and AMPcPP
分子名称: 5'-D(*AP*AP*AP*AP*A)-3', COBALT (II) ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
5BYI
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Human carbonic anhydrase II with an azobenzene inhibitor (1d)
分子名称: 4-(HYDROXYMERCURY)BENZOIC ACID, 4-[(E)-(4-aminophenyl)diazenyl]benzenesulfonamide, Carbonic anhydrase 2, ...
著者Groll, M, Broichhagen, J.
登録日2015-06-10
公開日2015-08-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Azobenzene-based inhibitors of human carbonic anhydrase II.
Beilstein J Org Chem, 11, 2015
2A14
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Crystal Structure of Human Indolethylamine N-methyltransferase with SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, indolethylamine N-methyltransferase
著者Dong, A, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-06-17
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Human Indolethylamine N-methyltransferase in complex with SAH.
To be Published
3I33
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Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in complex with ADP and inorganic phosphate
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock-related 70 kDa protein 2, ...
著者Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Kotzsch, A, Nielsen, T.K, Nordlund, P, Nyman, T, Moche, M, Persson, C, Roos, A.K, Sagemark, J, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Weigelt, J, Welin, M, Schueler, H, Structural Genomics Consortium (SGC)
登録日2009-06-30
公開日2009-07-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
Plos One, 5, 2010
2X1E
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The crystal structure of mature acyl coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum in complex 6- aminopenicillanic acid
分子名称: (2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ACYL-COENZYME, CHLORIDE ION, ...
著者Bokhove, M, Yoshida, H, Hensgens, C.M.H, van der Laan, J.M, Sutherland, J.D, Dijkstra, B.W.
登録日2009-12-23
公開日2010-03-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme.
Structure, 18, 2010
2A43
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Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif
分子名称: MAGNESIUM ION, RNA Pseudoknot
著者Pallan, P.S, Marshall, W.S, Harp, J, Jewett III, F.C, Wawrzak, Z, Brown II, B.A, Rich, A, Egli, M.
登録日2005-06-27
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif
Biochemistry, 44, 2005
2X4S
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Crystal structure of MHC CLass I HLA-A2.1 bound to a peptide representing the epitope of the H5N1 (Avian Flu) Nucleoprotein
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-2-MICROGLOBULIN, GLYCEROL, ...
著者Celie, P.H.N, Toebes, M, Rodenko, B, Ovaa, H, Perrakis, A, Schumacher, T.N.M.
登録日2010-02-02
公開日2010-03-02
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Uv-Induced Ligand Exchange in Mhc Class I Protein Crystals
J.Am.Chem.Soc., 131, 2009
4I2J
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Binary complex of mouse TdT with dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA nucleotidylexotransferase, ZINC ION
著者Gouge, J, Delarue, M.
登録日2012-11-21
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of Intermediates along the Catalytic Cycle of Terminal Deoxynucleotidyltransferase: Dynamical Aspects of the Two-Metal Ion Mechanism.
J.Mol.Biol., 425, 2013
5C17
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Crystal structure of the mercury-bound form of MerB2
分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, MERCURY (II) ION, ...
著者Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G.
登録日2015-06-13
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
Biochemistry, 55, 2016
2X7O
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Crystal structure of TGFbRI complexed with an indolinone inhibitor
分子名称: (3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]AMINO}METHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-6-CARBOXAMIDE, TGF-BETA RECEPTOR TYPE I
著者Roth, G.J, Heckel, A, Brandl, T, Grauert, M, Hoerer, S, Kley, J.T, Schnapp, G, Baum, P, Mennerich, D, Schnapp, A, Park, J.E.
登録日2010-03-03
公開日2010-10-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri)
J.Med.Chem., 53, 2010
4I6J
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A ubiquitin ligase-substrate complex
分子名称: Cryptochrome-2, F-box/LRR-repeat protein 3, S-phase kinase-associated protein 1
著者Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N.
登録日2012-11-29
公開日2013-03-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.
Nature, 496, 2013
3P35
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Polo-like kinase I Polo-box domain in complex with MQSpSPL phosphopeptide
分子名称: GLYCEROL, Serine/threonine-protein kinase PLK1, phosphopeptide
著者Sledz, P, Hyvonen, M, Abell, C.
登録日2010-10-04
公開日2011-04-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1
Angew.Chem.Int.Ed.Engl., 50, 2011
5C1I
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m1A58 tRNA methyltransferase mutant - D170A
分子名称: SULFATE ION, tRNA (adenine(58)-N(1))-methyltransferase TrmI
著者Ponchon, L, Degut, C, Folly-Klan, M, Barraud, P, Tisne, C.
登録日2015-06-14
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The m1A58 modification in eubacterial tRNA: An overview of tRNA recognition and mechanism of catalysis by TrmI.
Biophys.Chem., 210, 2016
3P4Q
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Crystal structure of Menaquinol:oxidoreductase in complex with oxaloacetate
分子名称: FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Tomasiak, T.M, Archuleta, T.L, Andrell, J, Luna-Chavez, C, Davis, T.A, Sarwar, M, Ham, A.J, McDonald, W.H, Yankowskaya, V, Stern, H.A, Johnston, J.N, Maklashina, E, Cecchini, G, Iverson, T.M.
登録日2010-10-06
公開日2010-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
J.Biol.Chem., 286, 2011
4I76
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Crystal structure of transcriptional regulator TM1030 with octanol
分子名称: 1,2-ETHANEDIOL, OCTAN-1-OL, Transcriptional regulator, ...
著者Koclega, K.D, Chruszcz, M, Cooper, D.R, Petkowski, J.J, Tkaczuk, K.L, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
登録日2012-11-30
公開日2013-01-02
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of transcriptional regulator TM1030 with octanol
To be Published

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