3I33

Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in complex with ADP and inorganic phosphate

Summary for 3I33

Entry DOI	10.2210/pdb3i33/pdb
Related	3FE1 3GDQ
Descriptor	Heat shock-related 70 kDa protein 2, PHOSPHATE ION, ADENOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	protein-adp complex, atp-binding, chaperone, nucleotide-binding, phosphoprotein, stress response, structural genomics, structural genomics consortium, sgc
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	45083.79
Authors	Wisniewska, M.,Karlberg, T.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Kotenyova, T.,Kotzsch, A.,Nielsen, T.K.,Nordlund, P.,Nyman, T.,Moche, M.,Persson, C.,Roos, A.K.,Sagemark, J.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van den Berg, S.,Weigelt, J.,Welin, M.,Schueler, H.,Structural Genomics Consortium (SGC) (deposition date: 2009-06-30, release date: 2009-07-21, Last modification date: 2023-11-01)
Primary citation	Wisniewska, M.,Karlberg, T.,Lehtio, L.,Johansson, I.,Kotenyova, T.,Moche, M.,Schueler, H. Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5:e8625-e8625, 2010 Cited by PubMed: 20072699 DOI: 10.1371/journal.pone.0008625 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation