3FE1
Crystal structure of the human 70kDa heat shock protein 6 (Hsp70B') ATPase domain in complex with ADP and inorganic phosphate
Summary for 3FE1
Entry DOI | 10.2210/pdb3fe1/pdb |
Descriptor | Heat shock 70 kDa protein 6, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (7 entities in total) |
Functional Keywords | mixed beta-sheet, atp-binding, nucleotide-binding, polymorphism, stress response, chaperone, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 135169.29 |
Authors | Wisniewska, M.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, A.,Johansson, I.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nilsson, M.E.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Siponen, M.I.,Thorsell, A.G.,Tresaugues, L.,Van Den Berg, S.,Weigelt, J.,Welin, M.,Wikstrom, M.,Schueler, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-11-27, release date: 2008-12-16, Last modification date: 2023-11-01) |
Primary citation | Wisniewska, M.,Karlberg, T.,Lehtio, L.,Johansson, I.,Kotenyova, T.,Moche, M.,Schueler, H. Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5:e8625-e8625, 2010 Cited by PubMed: 20072699DOI: 10.1371/journal.pone.0008625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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