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3I33

Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in complex with ADP and inorganic phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Heat shock-related 70 kDa protein 2polymer40444445.21UniProt (P54652)
Pfam (PF00012)
Homo sapiens (human)Heat shock 70 kDa protein 2, Hsp70-2
2B
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3C
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
6F
(A)
waterwater18.0345Chemie (HOH)
Sequence modifications
A: 6 - 386 (UniProt: P54652)
PDBExternal DatabaseDetails
Met -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
Ser -10-expression tag
Ser -9-expression tag
Gly -8-expression tag
Val -7-expression tag
Asp -6-expression tag
Leu -5-expression tag
Gly -4-expression tag
Thr -3-expression tag
Glu -2-expression tag
Asn -1-expression tag
Leu 0-expression tag
Tyr 1-expression tag
Phe 2-expression tag
Gln 3-expression tag
Ser 4-expression tag
Met 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight44445.2
Non-Polymers*Number of molecules4
Total formula weight638.6
All*Total formula weight45083.8
*Water molecules are not included.

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PDB entries from 2025-07-30

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