3P35

Polo-like kinase I Polo-box domain in complex with MQSpSPL phosphopeptide

Summary for 3P35

Entry DOI	10.2210/pdb3p35/pdb
Related	3P2W 3P2Z 3P34 3P36 3P37
Descriptor	Serine/threonine-protein kinase PLK1, phosphopeptide, GLYCEROL, ... (4 entities in total)
Functional Keywords	phosphoprotein binding domain, plk1, transferase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P53350
Total number of polymer chains	5
Total formula weight	82258.61
Authors	Sledz, P.,Hyvonen, M.,Abell, C. (deposition date: 2010-10-04, release date: 2011-04-27, Last modification date: 2024-10-30)
Primary citation	Sledz, P.,Stubbs, C.J.,Lang, S.,Yang, Y.Q.,McKenzie, G.J.,Venkitaraman, A.R.,Hyvonen, M.,Abell, C. From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1 Angew.Chem.Int.Ed.Engl., 50:4003-4006, 2011 Cited by PubMed: 21472932 DOI: 10.1002/anie.201008019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation