3P35
Polo-like kinase I Polo-box domain in complex with MQSpSPL phosphopeptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 595 |
| Chain | Residue |
| A | ASN385 |
| A | PRO389 |
| A | ALA577 |
| A | ARG581 |
| B | GLU504 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 596 |
| Chain | Residue |
| B | GLN536 |
| B | ASP537 |
| B | HIS538 |
| A | ARG507 |
| A | LEU508 |
| A | TYR510 |
| A | SER526 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 595 |
| Chain | Residue |
| B | THR459 |
| B | GLU460 |
| B | HOH601 |
| C | HOH10 |
| C | TRP414 |
| C | LEU490 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 596 |
| Chain | Residue |
| B | LEU566 |
| B | GLU569 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 597 |
| Chain | Residue |
| B | TYR421 |
| B | PHE436 |
| B | ASN437 |
| B | ASP438 |
| B | LYS475 |
| B | HOH598 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | SER375 | |
| A | SER450 | |
| B | SER375 | |
| B | SER450 | |
| C | SER375 | |
| C | SER450 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR498 | |
| B | THR498 | |
| C | THR498 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23455478 |
| Chain | Residue | Details |
| A | LYS492 | |
| B | LYS492 | |
| C | LYS492 |
