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PDB: 51964 件

3CYF
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Crystal Structure of E18N DJ-1
分子名称: Protein DJ-1
著者Witt, A.C, Lakshminarasimhan, M, Remington, B.C, Hasim, S, Pozharski, E, Wilson, M.A.
登録日2008-04-25
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
6RC5
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BU of 6rc5 by Molmil
Crystal structure of NAD kinase 1 from Listeria monocytogenes in complexe with an adenine derivative
分子名称: 9-ethyl-8-ethynyl-purin-6-amine, CITRIC ACID, NAD kinase 1
著者Gelin, M, Labesse, G.
登録日2019-04-11
公開日2020-02-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.038 Å)
主引用文献From Substrate to Fragments to Inhibitor ActiveIn VivoagainstStaphylococcus aureus.
Acs Infect Dis., 6, 2020
3U2Z
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BU of 3u2z by Molmil
Activator-Bound Structure of Human Pyruvate Kinase M2
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-(3-aminobenzyl)-4-methyl-2-methylsulfinyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, Pyruvate kinase isozymes M1/M2, ...
著者Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Inglese, J, Park, H, Structural Genomics Consortium (SGC)
登録日2011-10-04
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat.Chem.Biol., 8, 2012
6JO5
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BU of 6jo5 by Molmil
Structure of the green algal photosystem I supercomplex with light-harvesting complex I
分子名称: (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Suga, M, Miyazaki, N, Takahashi, Y.
登録日2019-03-20
公開日2019-06-19
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the green algal photosystem I supercomplex with a decameric light-harvesting complex I.
Nat.Plants, 5, 2019
4J96
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Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic Gain-of-Function K659M Mutation Identified in Cervical Cancer.
分子名称: CITRATE ANION, Fibroblast growth factor receptor 2, MAGNESIUM ION, ...
著者Chen, H, Mohammadi, M.
登録日2013-02-15
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2972 Å)
主引用文献Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
6FU4
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BU of 6fu4 by Molmil
Ligand binding domain (LBD) of the p. aeruginosa histamine receptor TlpQ
分子名称: ACETATE ION, GLYCEROL, HISTAMINE, ...
著者Gavira, J.A, Krell, T, Conejero-Muriel, M, Corral-Lugo, A, Matilla, M.A, Silva Jimenez, H, Mesa Torres, N, Martin-Mora, D.
登録日2018-02-26
公開日2018-05-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa.
MBio, 9, 2018
1KFK
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BU of 1kfk by Molmil
Crystal structure of Tryptophan Synthase From Salmonella Typhimurium
分子名称: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ...
著者Kulik, V, Weyand, M, Seidel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I.
登録日2001-11-21
公開日2003-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.
J.Mol.Biol., 324, 2002
2XME
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BU of 2xme by Molmil
The X-ray structure of CTP:inositol-1-phosphate cytidylyltransferase from Archaeoglobus fulgidus
分子名称: CTP-INOSITOL-1-PHOSPHATE CYTIDYLYLTRANSFERASE, GLYCEROL
著者Brito, J.A, Borges, N, Vonrhein, C, Santos, H, Archer, M.
登録日2010-07-27
公開日2011-05-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of Archaeoglobus Fulgidus Ctp:Inositol-1-Phosphate Cytidylyltransferase, a Key Enzyme for Di-Myo-Inositol-Phosphate Synthesis in (Hyper)Thermophiles.
J.Bacteriol., 193, 2011
4NEZ
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BU of 4nez by Molmil
Crystal Structure of an engineered protein with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR276
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Engineered protein OR276, tetrabutylphosphonium
著者Guan, R, Lin, Y.-R, Koga, N, Koga, R, Castellanos, J, Seetharaman, J, Maglaqui, M, Sahdev, S, Mao, L, Xiao, R, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2013-10-30
公開日2014-01-15
実験手法X-RAY DIFFRACTION (2.395 Å)
主引用文献Northeast Structural Genomics Consortium Target OR276
To be published
2CLQ
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BU of 2clq by Molmil
Structure of mitogen-activated protein kinase kinase kinase 5
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, STAUROSPORINE
著者Bunkoczi, G, Salah, E, Fedorov, O, Pike, A, Gileadi, O, von Delft, F, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Knapp, S.
登録日2006-04-28
公開日2006-05-09
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Functional Characterization of the Human Protein Kinase Ask1.
Structure, 15, 2007
4NFA
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BU of 4nfa by Molmil
Structure of the C-terminal doamin of Knl1
分子名称: CHLORIDE ION, GLYCEROL, Protein CASC5
著者Petrovic, A, Mosalaganti, S, Keller, J, Mattiuzzo, M, Overlack, K, Wohlgemuth, S, Pasqualato, S, Raunser, S, Musacchio, A.
登録日2013-10-31
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.497 Å)
主引用文献Modular Assembly of RWD Domains on the Mis12 Complex Underlies Outer Kinetochore Organization.
Mol.Cell, 53, 2014
1KFX
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BU of 1kfx by Molmil
Crystal Structure of Human m-Calpain Form I
分子名称: M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
著者Strobl, S, Fernandez-Catalan, C, Braun, M, Huber, R, Masumoto, H, Nakagawa, K, Irie, A, Sorimachi, H, Bourenkow, G, Bartunik, H, Suzuki, K, Bode, W.
登録日2001-11-23
公開日2001-12-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000
3CNW
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BU of 3cnw by Molmil
Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196.
分子名称: Protein XoxI
著者Kuzin, A.P, Abashidze, M, Seetharaman, J, Wang, H, Ciccosanti, C, Mao, L, Xiao, R, Nair, R, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2008-03-26
公開日2008-04-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Three-dimensional structure of the protein XoxI (Q81AY6) from Bacillus cereus. Northeast Structural Genomics Consortium target BcR196.
To Be Published
1KQV
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BU of 1kqv by Molmil
Family of NMR Solution Structures of Ca Ln Calbindin D9K
分子名称: LANTHANUM (III) ION, VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN
著者Bertini, I, Donaire, A, Jimenez, B, Luchinat, C, Parigi, G, Piccioli, M, Poggi, L.
登録日2002-01-08
公開日2002-01-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Paramagnetism-based versus classical constraints: an analysis of the solution structure of Ca Ln calbindin D9k.
J.Biomol.NMR, 21, 2001
6FOE
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BU of 6foe by Molmil
BaxB01 Fab fragment
分子名称: Fab BaxB01 heavy chain, Fab BaxB01 light chain
著者Hollerweger, J, Schinagl, A, Kerschbaumer, R.J, Scheiflinger, F, Thiele, M, Goettig, P, Brandstetter, H.
登録日2018-02-07
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.
Biochemistry, 57, 2018
1KS9
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BU of 1ks9 by Molmil
Ketopantoate Reductase from Escherichia coli
分子名称: 2-DEHYDROPANTOATE 2-REDUCTASE
著者Matak-Vinkovic, D, Vinkovic, M, Saldanha, S.A, Ashurst, J.A, von Delft, F, Inoue, T, Miguel, R.N, Smith, A.G, Blundell, T.L, Abell, C.
登録日2002-01-11
公開日2002-01-25
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.
Biochemistry, 40, 2001
6R6O
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BU of 6r6o by Molmil
Recombinantly produced Kusta0087/Kusta0088 Complex, C32G/wt mutant
分子名称: HEME C, Kusta0088, POTASSIUM ION, ...
著者Akram, M, Barends, T.
登録日2019-03-27
公開日2019-10-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A nitric oxide-binding heterodimeric cytochromeccomplex from the anammox bacteriumKuenenia stuttgartiensisbinds to hydrazine synthase.
J.Biol.Chem., 294, 2019
6JN2
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BU of 6jn2 by Molmil
Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10
著者Song, X, Wang, M, Yang, N, Xu, R.M.
登録日2019-03-13
公開日2019-09-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6R76
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BU of 6r76 by Molmil
Crystal structure of trans-3-Hydroxy-L-proline dehydratase from Thermococcus litoralis - open conformation
分子名称: Proline racemase
著者Ferraris, D.M, Miggiano, R, Rizzi, M.
登録日2019-03-28
公開日2019-07-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form.
Biochem.Biophys.Res.Commun., 516, 2019
3CRB
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BU of 3crb by Molmil
Crystal structure of the complex of C-lobe of lactoferrin with 2-chromenone at 2.6 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COUMARIN, ...
著者Vikram, G, Mir, R, Sinha, M, Singh, N, Kaur, P, Sharma, S, Singh, T.P.
登録日2008-04-05
公開日2008-04-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the complex of C-lobe of lactoferrin with 2-chromenone at 2.6 A resolution
To be Published
3OSV
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BU of 3osv by Molmil
The crytsal structure of FLGD from P. Aeruginosa
分子名称: Flagellar basal-body rod modification protein FlgD, GLYCEROL
著者Wang, D, Luo, M, Niu, S.
登録日2010-09-10
公開日2011-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of a novel dimer form of FlgD from P. aeruginosa PAO1
Proteins, 79, 2011
3D1P
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BU of 3d1p by Molmil
Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae
分子名称: ACETATE ION, CHLORIDE ION, Putative thiosulfate sulfurtransferase YOR285W
著者Nocek, B, Evdokimova, E, Kudritska, M, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-05-06
公開日2008-07-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Atomic resolution structure of uncharacterized protein from Saccharomyces cerevisiae.
To be Published
3CRH
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BU of 3crh by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
4JDQ
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BU of 4jdq by Molmil
Structure of the Fluorescence Recovery Protein from Synechocystis sp PCC 6803, R60K mutant
分子名称: Slr1964 protein
著者Sutter, M, Kerfeld, C.A.
登録日2013-02-25
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献Crystal structure of the FRP and identification of the active site for modulation of OCP-mediated photoprotection in cyanobacteria.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JE0
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BU of 4je0 by Molmil
Structures of SdrD from Staphylococcus aureus reveal the molecular mechanism of how the cell surface receptors recognize their ligands
分子名称: CALCIUM ION, Ser-Asp rich fibrinogen/bone sialoprotein-binding protein SdrD
著者Wang, X, Ge, J, Yang, M.
登録日2013-02-25
公開日2013-06-19
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of SdrD from Staphylococcus aureus reveal the molecular mechanism of how the cell surface receptors recognize their ligands
Protein Cell, 4, 2013

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