3ECQ
| Endo-alpha-N-acetylgalactosaminidase from Streptococcus pneumoniae: SeMet structure | 分子名称: | CALCIUM ION, Endo-alpha-N-acetylgalactosaminidase, GLYCEROL, ... | 著者 | Caines, M.E.C, Zhu, H, Vuckovic, M, Strynadka, N.C.J. | 登録日 | 2008-09-01 | 公開日 | 2008-09-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae: a target for structure-based vaccine design. J.Biol.Chem., 283, 2008
|
|
3EEB
| Structure of the V. cholerae RTX cysteine protease domain | 分子名称: | INOSITOL HEXAKISPHOSPHATE, RTX toxin RtxA, SODIUM ION | 著者 | Lupardus, P.J, Shen, A, Bogyo, M, Garcia, K.C. | 登録日 | 2008-09-04 | 公開日 | 2008-10-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain Science, 322, 2008
|
|
6EZH
| Torpedo californica AChE in complex with indolic multi-target directed ligand | 分子名称: | 1-(7-chloranyl-4-methoxy-1~{H}-indol-5-yl)-3-[1-(cyclohexylmethyl)piperidin-4-yl]propan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase | 著者 | Santoni, G, Lalut, J, Karila, D, Lecoutey, C, Davis, A, Nachon, F, Sillman, I, Sussman, J, Weik, M, Maurice, T, Dallemagne, P, Rochais, C. | 登録日 | 2017-11-15 | 公開日 | 2018-11-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Novel multitarget-directed ligands targeting acetylcholinesterase and sigma1receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase. Eur J Med Chem, 162, 2018
|
|
4J4S
| Triple mutant SFTAVN | 分子名称: | Nucleocapsid protein, SODIUM ION | 著者 | Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J. | 登録日 | 2013-02-07 | 公開日 | 2013-05-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.442 Å) | 主引用文献 | Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential J.Virol., 87, 2013
|
|
1IZE
| Crystal structure of Aspergillus oryzae Aspartic proteinase complexed with pepstatin | 分子名称: | Pepstatin, alpha-D-mannopyranose, aspartic proteinase | 著者 | Kamitori, S, Ohtaki, A, Ino, H, Takeuchi, M. | 登録日 | 2002-10-02 | 公開日 | 2003-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of Aspergillus oryzae aspartic proteinase and its complex with an inhibitor pepstatin at 1.9A resolution. J.Mol.Biol., 326, 2003
|
|
6SDH
| Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 5 mM | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Gloeckner, S, Haake, M, Heine, A, Klebe, G. | 登録日 | 2019-07-27 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 5 mM To Be Published
|
|
3EFP
| |
1J3D
| |
3PLX
| The crystal structure of aspartate alpha-decarboxylase from Campylobacter jejuni subsp. jejuni NCTC 11168 | 分子名称: | ACETATE ION, Aspartate 1-decarboxylase, DI(HYDROXYETHYL)ETHER | 著者 | Tan, K, Gu, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-11-15 | 公開日 | 2010-12-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | The crystal structure of aspartate alpha-decarboxylase from Campylobacter jejuni subsp. jejuni NCTC 11168 To be Published
|
|
6SBF
| Structure of type II terpene cyclase MstE_Y157F from Scytonema (apo) | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, MstE | 著者 | Moosmann, P, Ecker, F, Leopold-Messer, S, Cahn, J.K.B, Groll, M, Piel, J. | 登録日 | 2019-07-19 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A monodomain class II terpene cyclase assembles complex isoprenoid scaffolds. Nat.Chem., 12, 2020
|
|
4ISR
| Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II | 分子名称: | Neurotoxin, SULFATE ION, Synaptotagmin-2 | 著者 | Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. | 登録日 | 2013-01-17 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II. Structure, 21, 2013
|
|
3EL4
| Crystal structure of inhibitor saquinavir (SQV) complexed with the multidrug HIV-1 protease variant L63P/V82T/I84V | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETATE ION, Protease | 著者 | Prabu-Jeyabalan, M, King, N, Schiffer, C. | 登録日 | 2008-09-19 | 公開日 | 2009-09-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Extreme Entropy-Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease. Acs Chem.Biol., 7, 2012
|
|
4O92
| Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747 | 分子名称: | Glutathione S-transferase, SULFATE ION | 著者 | Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Glenn, A.S, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-12-31 | 公開日 | 2014-01-15 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structure of a Glutathione S-transferase from Pichia kudriavzevii (Issatchenkia orientalis), target EFI-501747 TO BE PUBLISHED
|
|
6SEG
| Class1: CENP-A nucleosome in complex with CENP-C central region | 分子名称: | DNA (145-MER), Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, ... | 著者 | Ali-Ahmad, A, Bilokapic, S, Schafer, I.B, Halic, M, Sekulic, N. | 登録日 | 2019-07-30 | 公開日 | 2019-08-14 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail. Embo Rep., 20, 2019
|
|
4O9M
| Human DNA polymerase beta complexed with adenylated tetrahydrofuran (abasic site) containing DNA | 分子名称: | (5'-D(P*GP*TP*CP*GP*G)-3');, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ... | 著者 | Caglayan, M, Batra, V.K, Sassa, A, Prasad, R, Wilson, S.H. | 登録日 | 2014-01-02 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Role of polymerase beta in complementing aprataxin deficiency during abasic-site base excision repair. Nat.Struct.Mol.Biol., 21, 2014
|
|
4IWY
| SeMet-substituted RimK structure | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Ribosomal protein S6 modification protein, ... | 著者 | Shi, D, Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M. | 登録日 | 2013-01-24 | 公開日 | 2013-05-08 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and function of Escherichia coli RimK, an ATP-grasp fold, l-glutamyl ligase enzyme. Proteins, 81, 2013
|
|
6IWH
| Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with C14-GGGI lipopeptide | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, C14-GGGI lipopeptide, ... | 著者 | Yamamoto, Y, Morita, D, Sugita, M. | 登録日 | 2018-12-05 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Identification and Structure of an MHC Class I-Encoded Protein with the Potential to PresentN-Myristoylated 4-mer Peptides to T Cells. J Immunol., 202, 2019
|
|
1J1O
| Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | 登録日 | 2002-12-13 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
|
|
1J7S
| Crystal Structure of deoxy HbalphaYQ, a mutant of HbA | 分子名称: | Hemoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Miele, A.E, Draghi, F, Arcovito, A, Bellelli, A, Brunori, M, Travaglini-Allocatelli, C, Vallone, B. | 登録日 | 2001-05-18 | 公開日 | 2002-02-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Control of heme reactivity by diffusion: structural basis and functional characterization in hemoglobin mutants. Biochemistry, 40, 2001
|
|
6F0N
| GLIC mutant E82A | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Hu, H.D, Delarue, M. | 登録日 | 2017-11-20 | 公開日 | 2018-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel. PLoS Biol., 15, 2017
|
|
1J1X
| Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | 著者 | Yokota, A, Tsumoto, K, Shiroishi, M, Kondo, H, Kumagai, I. | 登録日 | 2002-12-20 | 公開日 | 2003-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Role of Hydrogen Bonding via Interfacial Water Molecules in Antigen-Antibody Complexation. THE HyHEL-10-HEL INTERACTION J.BIOL.CHEM., 278, 2003
|
|
6F2V
| Crystal structure of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) in complex with AMP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | 著者 | Dohler, C, Zebisch, M, Strater, N. | 登録日 | 2017-11-27 | 公開日 | 2018-08-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and substrate binding mode of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3). Sci Rep, 8, 2018
|
|
3EPO
| Crystal structure of Caulobacter crescentus ThiC complexed with HMP-P | 分子名称: | (4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL DIHYDROGEN PHOSPHATE, Thiamine biosynthesis protein thiC | 著者 | Li, S, Chatterjee, A, Zhang, Y, Grove, T.L, Lee, M, Krebs, C, Booker, S.J, Begley, T.P, Ealick, S.E. | 登録日 | 2008-09-29 | 公開日 | 2008-10-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily Nat.Chem.Biol., 4, 2008
|
|
6F15
| GLIC mutant H127Q | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Hu, H.D, Delarue, M. | 登録日 | 2017-11-21 | 公開日 | 2018-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel. PLoS Biol., 15, 2017
|
|
3PHU
| OTU Domain of Crimean Congo Hemorrhagic Fever Virus | 分子名称: | GLYCEROL, RNA-directed RNA polymerase L | 著者 | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | 登録日 | 2010-11-04 | 公開日 | 2011-02-02 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|