6BX8
| Human Mesotrypsin (PRSS3) Complexed with Tissue Factor Pathway Inhibitor Variant (TFPI1-KD1-K15R-I17C-I34C) | 分子名称: | SULFATE ION, Tissue factor pathway inhibitor, Trypsin-3 | 著者 | Coban, M, Sankaran, B, Cohen, I, Hockla, A, Papo, N, Radisky, E.S. | 登録日 | 2017-12-18 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin. J. Biol. Chem., 294, 2019
|
|
6BXN
| Crystal structure of Candidatus Methanoperedens nitroreducens Dph2 with 4Fe-4S cluster and SAM | 分子名称: | Diphthamide biosynthesis enzyme Dph2, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE | 著者 | Fenwick, M.K, Torelli, A.T, Zhang, Y, Dong, M, Kathiresan, V, Carantoa, J.D, Dzikovski, B, Lancaster, K.M, Freed, J.H, Hoffman, B.M, Lin, H, Ealick, S.E. | 登録日 | 2017-12-18 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.079 Å) | 主引用文献 | Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science, 359, 2018
|
|
6C23
| Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | 著者 | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | 登録日 | 2018-01-05 | 公開日 | 2018-01-24 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
|
|
1YKG
| Solution structure of the flavodoxin-like domain from the Escherichia coli sulfite reductase | 分子名称: | FLAVIN MONONUCLEOTIDE, Sulfite reductase [NADPH] flavoprotein alpha-component | 著者 | Sibille, N, Blackledge, M, Brutscher, B, Coves, J, Bersch, B. | 登録日 | 2005-01-18 | 公開日 | 2005-07-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Sulfite Reductase Flavodoxin-like Domain from Escherichia coli Biochemistry, 44, 2005
|
|
6BXZ
| Crystal Structure of Pig Protocadherin-15 EC10-MAD12 | 分子名称: | CALCIUM ION, Protocadherin related 15 | 著者 | De-la-Torre, P, Araya-Secchi, R, Choudhary, D, Sotomayor, M. | 登録日 | 2017-12-19 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | A Mechanically Weak Extracellular Membrane-Adjacent Domain Induces Dimerization of Protocadherin-15. Biophys. J., 115, 2018
|
|
6BYS
| Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PRKAc alpha | 分子名称: | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit | 著者 | Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P. | 登録日 | 2017-12-21 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.75 Å) | 主引用文献 | Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha. Structure, 27, 2019
|
|
2N9K
| 1H, 13C, and 15N Chemical Shift Assignments for in vitro GB1 | 分子名称: | Immunoglobulin G-binding protein G | 著者 | Ikeya, T, Hanashima, T, Hosoya, S, Shimazaki, M, Ikeda, S, Mishima, M, Guentert, P, Ito, Y. | 登録日 | 2015-11-26 | 公開日 | 2016-12-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Improved in-cell structure determination of proteins at near-physiological concentration Sci Rep, 6, 2016
|
|
1YO7
| |
2NDO
| Structure of EcDsbA-sulfonamide1 complex | 分子名称: | 2-{[(4-iodophenyl)sulfonyl]amino}benzoic acid, Thiol:disulfide interchange protein DsbA | 著者 | Williams, M.L, Doak, B.C, Vazirani, M, Ilyichova, O, Wang, G, Bermel, W, Simpson, J.S, Chalmers, D.K, King, G.F, Mobli, M, Scanlon, M.J. | 登録日 | 2016-08-22 | 公開日 | 2017-02-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of ligand binding modes in weak protein-ligand complexes using sparse NMR data. J.Biomol.Nmr, 66, 2016
|
|
2NC8
| |
2N4O
| |
1LJE
| |
6BZV
| Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3 | 分子名称: | 19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide | 著者 | Tzarum, N, Aleman, F, Wilson, I.A, Law, M. | 登録日 | 2017-12-26 | 公開日 | 2018-06-20 | 最終更新日 | 2022-02-02 | 実験手法 | X-RAY DIFFRACTION (2.654 Å) | 主引用文献 | Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5OHF
| Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide, partially reduced | 分子名称: | CHLORIDE ION, CYANIDE ION, Globin-coupled histidine kinase, ... | 著者 | Skalova, T, Kolenko, P, Dohnalek, J, Stranava, M, Martinkova, M. | 登録日 | 2017-07-16 | 公開日 | 2017-11-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction. J. Biol. Chem., 292, 2017
|
|
6C83
| Structure of Aurora A (122-403) bound to inhibitory Monobody Mb2 and AMPPCP | 分子名称: | Aurora kinase A, Mb2 Monobody, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Hoemberger, M, Kutter, S, Zorba, A, Nguyen, V, Shohei, A, Shohei, K, Kern, D. | 登録日 | 2018-01-24 | 公開日 | 2019-02-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Allosteric modulation of a human protein kinase with monobodies. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
1LLU
| THE TERNARY COMPLEX OF PSEUDOMONAS AERUGINOSA ALCOHOL DEHYDROGENASE WITH ITS COENZYME AND WEAK SUBSTRATE | 分子名称: | 1,2-ETHANEDIOL, Alcohol Dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Levin, I, Meiri, G, Peretz, M, Frolow, F, Burstein, Y. | 登録日 | 2002-04-30 | 公開日 | 2003-11-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The ternary complex of Pseudomonas aeruginosa alcohol dehydrogenase with NADH and ethylene glycol. Protein Sci., 13, 2004
|
|
6BKD
| Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3D | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab AR3D heavy chain, Fab AR3D light chain, ... | 著者 | Tzarum, N, Wilson, I.A, Law, M. | 登録日 | 2017-11-08 | 公開日 | 2018-12-26 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Genetic and structural insights into broad neutralization of hepatitis C virus by human VH1-69 antibodies. Sci Adv, 5, 2019
|
|
3MMK
| The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification | 分子名称: | CHLORIDE ION, Fusion of LIM/homeobox protein Lhx4, linker, ... | 著者 | Gadd, M.S, Langley, D.B, Guss, J.M, Matthews, J.M. | 登録日 | 2010-04-20 | 公開日 | 2011-07-13 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.157 Å) | 主引用文献 | The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification. J.Biol.Chem., 2011
|
|
1JIT
| |
2OE2
| MSrecA-native-low humidity 95% | 分子名称: | PHOSPHATE ION, Protein recA | 著者 | Krishna, R, Rajan Prabu, J, Manjunath, G.P, Datta, S, Chandra, N.R, Muniyappa, K, Vijayan, M. | 登録日 | 2006-12-28 | 公開日 | 2007-06-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA J.Mol.Biol., 367, 2007
|
|
1JJI
| The Crystal Structure of a Hyper-thermophilic Carboxylesterase from the Archaeon Archaeoglobus fulgidus | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Carboxylesterase | 著者 | De Simone, G, Menchise, V, Manco, G, Mandrich, L, Sorrentino, N, Lang, D, Rossi, M, Pedone, C. | 登録日 | 2001-07-06 | 公開日 | 2001-12-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus. J.Mol.Biol., 314, 2001
|
|
2OK7
| Ferredoxin-NADP+ reductase from Plasmodium falciparum with 2'P-AMP | 分子名称: | ADENOSINE-2'-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, Putative ferredoxin--NADP reductase, ... | 著者 | Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2007-01-16 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Ferredoxin-NADP(+) Reductase from Plasmodium falciparum Undergoes NADP(+)-dependent Dimerization and Inactivation: Functional and Crystallographic Analysis. J.Mol.Biol., 367, 2007
|
|
5AB3
| S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A | 分子名称: | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, SODIUM ION, [(2R,3S,4R,5R)-5-[4-AMINOCARBONYL-5-[[(Z)-[(3R,4R)-3,4-DIHYDROXY-2-OXO-5-PHOSPHONOOXY-PENTYL]IMINOMETHYL]AMINO]IMIDAZOL-1-YL]-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | 著者 | Guo, X, Soderholm, A, Newton, M, Nasvall, J, Andersson, D, Patrick, W, Selmer, M. | 登録日 | 2015-07-31 | 公開日 | 2016-09-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structural and functional innovations in the real-time evolution of new ( beta alpha )8 barrel enzymes. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
7ZT0
| Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | 分子名称: | 1-(2-piperazin-1-ylethyl)-5-pyridin-4-yl-indole-2-carboxamide, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Snee, M, Katariya, M, Levy, C, Leys, D. | 登録日 | 2022-05-09 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
|
|
7ZQR
| Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor | 分子名称: | 4-(4-methoxyphenyl)pyridine, CHLORIDE ION, GLYCEROL, ... | 著者 | Snee, M, Katariya, M, Tunnicliffe, R, Levy, C, Leys, D. | 登録日 | 2022-05-02 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
|
|