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PDB: 51689 件

7O0S
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Crystal structure of the N-terminal domain of CEP164(1-109) bound to camelid nanobody 36Z
分子名称: Centrosomal protein of 164 kDa, Nanobody 36Z
著者e Silva, I.R, van Breugel, M.
登録日2021-03-26
公開日2021-09-15
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
6NI4
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Pseudomonas fluorescens isocyanide hydratase at 277 K G150T mutant
分子名称: Isonitrile hydratase InhA
著者Wilson, M.A, Dasgupta, M, van den Bedem, H.
登録日2018-12-26
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.
Proc.Natl.Acad.Sci.USA, 116, 2019
7THA
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Crystal structure of human transthyretin variant C10A/M13V
分子名称: CALCIUM ION, Transthyretin
著者Jaeger, M, Mortenson, D.E, Yan, N.L, Kelly, J.W.
登録日2022-01-10
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lysine carbamylation competes with urea unfolding of human transthyretin introducing kinetic heterogeneity
To Be Published
5CM9
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Structural Basis for the Selectivity of Guanine Nucleotide Exchange Factors for the small G-protein Ral
分子名称: Ral guanine nucleotide dissociation stimulator-like 2, Ras-related protein Ral-a
著者Popovic, M, Schouten, A, Rehmann, H.
登録日2015-07-16
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of the Guanine Nucleotide Exchange Factor Rlf in complex with the small G-protein Ral identifies conformational intermediates of the exchange reaction and the basis for the selectivity.
J.Struct.Biol., 193, 2016
6QHE
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Alcohol Dehydrogenase from Arthrobacter sp. TS-15 in complex with NAD+
分子名称: Alcohol Dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION
著者Lockie, C, Beloti, L, Shanati, T, Ansorge-Schumacher, M, Grogan, G.
登録日2019-01-16
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Two Enantiocomplementary Ephedrine Dehydrogenases from Arthrobacter sp. TS-15 with Broad Substrate Specificity
Acs Catalysis, 9, 2019
6WHI
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Cryo-electron microscopy structure of the type I-F CRISPR RNA-guided surveillance complex bound to the anti-CRISPR AcrIF9
分子名称: CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, CRISPR-associated protein Csy3, ...
著者Hirschi, M, Santiago-Frangos, A, Wilkinson, R, Golden, S.M, Wiedenheft, B, Lander, G.
登録日2020-04-08
公開日2020-05-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex.
Nat Commun, 11, 2020
5CM8
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Structural Basis for the Selectivity of Guanine Nucleotide Exchange Factors for the small G-protein Ral
分子名称: Ral guanine nucleotide dissociation stimulator-like 2, Ras-related protein Ral-a
著者Popovic, M, Schouten, A, Rehmann, H.
登録日2015-07-16
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of the Guanine Nucleotide Exchange Factor Rlf in complex with the small G-protein Ral identifies conformational intermediates of the exchange reaction and the basis for the selectivity.
J.Struct.Biol., 193, 2016
6I09
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Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with denuded glycan obtained by soaking
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-methyl 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-beta-D-glucopyranoside, Endolytic peptidoglycan transglycosylase RlpA
著者Alcorlo, M, Hermoso, J.A.
登録日2018-10-25
公開日2019-11-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division.
Nat Commun, 10, 2019
6NJP
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Structure of the assembled ATPase EscN in complex with its central stalk EscO from the enteropathogenic E. coli (EPEC) type III secretion system
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, EscO, ...
著者Majewski, D.D, Worrall, L.J, Hong, C, Atkinson, C.E, Vuckovic, M, Watanabe, N, Yu, Z, Strynadka, N.C.J.
登録日2019-01-03
公開日2019-02-20
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry.
Nat Commun, 10, 2019
1UHG
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Crystal Structure of S-Ovalbumin At 1.9 Angstrom Resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovalbumin, ...
著者Yamasaki, M, Takahashi, N, Hirose, M.
登録日2003-07-03
公開日2003-07-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form
J.Biol.Chem., 278, 2003
6G5B
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Heme-carbene complex in myoglobin H64V/V68A containing an N-methylhistidine as the proximal ligand, 1.6 angstrom resolution
分子名称: ETHYL ACETATE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Tinzl, M, Hayashi, T, Mori, T, Hilvert, D.
登録日2018-03-29
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture and characterization of a reactive haem-carbenoid complex in an artificial metalloenzyme
Nat Catal, 1, 2018
7O86
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1.73A X-ray crystal structure of the conserved C-terminal (CCT) of human SPAK
分子名称: CALCIUM ION, MAGNESIUM ION, SODIUM ION, ...
著者Elvers, K.T, Bax, B.D, Lipka-Lloyd, M, Mehellou, Y.
登録日2021-04-14
公開日2021-09-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.
Chembiochem, 23, 2022
7OWB
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Chimeric carminomycin-4-O-methyltransferase (DnrK) with a region from 10-hydroxylase CalMB
分子名称: Carminomycin 4-O-methyltransferase DnrK,Methyltransferase domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate
著者Dinis, P, MetsaKetela, M.
登録日2021-06-17
公開日2022-07-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Evolution-inspired engineering of anthracycline methyltransferases.
Pnas Nexus, 2, 2023
1AVH
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BU of 1avh by Molmil
CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN ANNEXIN V AFTER REFINEMENT. IMPLICATIONS FOR STRUCTURE, MEMBRANE BINDING AND ION CHANNEL FORMATION OF THE ANNEXIN FAMILY OF PROTEINS
分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION
著者Huber, R, Berendes, R, Burger, A, Schneider, M, Karshikov, A, Luecke, H, Roemisch, J, Paques, E.
登録日1991-10-17
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins.
J.Mol.Biol., 223, 1992
6NCP
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Crystal structure of HIV-1 broadly neutralizing antibody ACS202
分子名称: ACS202 Fab heavy chain, ACS202 Fab light chain, GLYCINE, ...
著者Yuan, M, Wilson, I.A.
登録日2018-12-11
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
6PWC
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A complex structure of arrestin-2 bound to neurotensin receptor 1
分子名称: Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
著者Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E.
登録日2019-07-22
公開日2019-12-04
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Cell Res., 29, 2019
6PWX
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Cryo-EM structure of RbBP5 bound to the nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U.
登録日2019-07-23
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Nat Commun, 10, 2019
1YCM
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BU of 1ycm by Molmil
Solution Structure of matrix metalloproteinase 12 (MMP12) in the presence of N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acid (NNGH)
分子名称: CALCIUM ION, Macrophage metalloelastase, N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID, ...
著者Bertini, I, Calderone, V, Cosenza, M, Fragai, M, Lee, Y.M, Luchinat, C, Mangani, S, Terni, B, Turano, P, Structural Proteomics in Europe (SPINE)
登録日2004-12-22
公開日2005-04-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Conformational variability of matrix metalloproteinases: Beyond a single 3D structure.
Proc.Natl.Acad.Sci.Usa, 102, 2005
4OHQ
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Crystal structure of chloroplast triose phosphate isomerase from Arabidopsis thaliana
分子名称: Triosephosphate isomerase, chloroplastic
著者Lara-Gonzalez, S, Lopez-Castillo, M, Brieba, L.G.
登録日2014-01-17
公開日2015-01-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Basis for Redox Regulation of Cytoplasmic and Chloroplastic Triosephosphate Isomerases from Arabidopsis thaliana.
Front Plant Sci, 7, 2016
6WOV
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Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M.
登録日2020-04-25
公開日2020-08-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
6WU0
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CryoEM structure of Burkholderia pseudomallei hopanoid biosynthesis-associated RND transporter HpnN
分子名称: Hopanoid biosynthesis associated RND transporter like protein HpnN
著者Lyu, M, Yu, E.W.
登録日2020-05-04
公開日2021-02-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献A 'Build and Retrieve' methodology to simultaneously solve cryo-EM structures of membrane proteins.
Nat.Methods, 18, 2021
6WVR
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Tubulin dimers from a 13-protofilament, Taxol stabilized microtubule
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V.
登録日2020-05-06
公開日2020-05-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 117, 2020
7NXJ
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Crystal structure of human Cdk13/Cyclin K in complex with the inhibitor THZ531
分子名称: Cyclin-K, Cyclin-dependent kinase 13, N-[4-[(3R)-3-[[5-chloranyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidin-1-yl]carbonylphenyl]-4-(dimethylamino)butanamide
著者Anand, K, Greifenberg, A.K, Kaltheuner, I.H, Geyer, M.
登録日2021-03-18
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma.
Eur.J.Med.Chem., 221, 2021
7S16
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Crystal structure of alpha-COP-WD40 domain R57A mutant
分子名称: Coatomer subunit alpha, SODIUM ION
著者Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S.
登録日2021-09-01
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022
7S22
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Crystal structure of alpha-COP-WD40 domain
分子名称: Coatomer subunit alpha
著者Dey, D, Singh, S, Khan, S, Martin, M, Schnicker, N, Gakhar, L, Pierce, B, Hasan, S.S.
登録日2021-09-02
公開日2022-02-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking
Commun Biol, 5, 2022

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件を2024-09-04に公開中

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